[go: up one dir, main page]

MX9306023A - Acidos quinoloncarboxilicos y procedimiento para su obtencion. - Google Patents

Acidos quinoloncarboxilicos y procedimiento para su obtencion.

Info

Publication number
MX9306023A
MX9306023A MX9306023A MX9306023A MX9306023A MX 9306023 A MX9306023 A MX 9306023A MX 9306023 A MX9306023 A MX 9306023A MX 9306023 A MX9306023 A MX 9306023A MX 9306023 A MX9306023 A MX 9306023A
Authority
MX
Mexico
Prior art keywords
obtaining
acids
chinoloncarboxylic
procedure
quinolone
Prior art date
Application number
MX9306023A
Other languages
English (en)
Inventor
Andreas Krebs
Thomas Schenke
Thomas Philipps
Klaus Grohe
Rainer Endermann
Klaus-Dieter Bremm
Uwe Petersen
Wilfried Schrock
Dieter Habich
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MX9306023A publication Critical patent/MX9306023A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La invención se refiere a nuevos derivados de los ácidos quinolon- y naftiridoncarboxílico, que están enlazados con un antibiótico B-lactámico, a sus sales, procedimiento para su obtención, así como a medios antibacterianos que los contienen.
MX9306023A 1992-10-09 1993-09-29 Acidos quinoloncarboxilicos y procedimiento para su obtencion. MX9306023A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4234078A DE4234078A1 (de) 1992-10-09 1992-10-09 Chinoloncarbonsäuren

Publications (1)

Publication Number Publication Date
MX9306023A true MX9306023A (es) 1994-05-31

Family

ID=6470084

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9306023A MX9306023A (es) 1992-10-09 1993-09-29 Acidos quinoloncarboxilicos y procedimiento para su obtencion.

Country Status (19)

Country Link
US (1) US5480879A (es)
EP (1) EP0591808A1 (es)
JP (1) JPH0820587A (es)
KR (1) KR940009193A (es)
CN (1) CN1090285A (es)
AU (1) AU666772B2 (es)
CA (1) CA2107812A1 (es)
CZ (1) CZ9302001A3 (es)
DE (1) DE4234078A1 (es)
FI (1) FI934411A7 (es)
HU (1) HUT66376A (es)
IL (1) IL107188A0 (es)
MX (1) MX9306023A (es)
NO (1) NO933393L (es)
NZ (1) NZ248871A (es)
PL (1) PL300628A1 (es)
SK (1) SK109293A3 (es)
TW (1) TW288018B (es)
ZA (1) ZA937474B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7706394A (en) * 1994-02-25 1995-09-11 Arrieta Munguia, Judith Marcia Quinolonylcarboxamidocephalosporin derivatives and pharmaceutical compositions containing them
AU718806B2 (en) * 1995-02-17 2000-04-20 Daiichi Asubio Pharma Co., Ltd. Penem derivatives and antimicrobial agent containing the same
DE19546249A1 (de) 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
RU2193558C2 (ru) * 1997-09-15 2002-11-27 Дзе Проктер Энд Гэмбл Компани Производные хинолона и фармацевтическая композиция на их основе
DE19751948A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
DE19821039A1 (de) 1998-05-11 1999-11-18 Bayer Ag Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6716830B2 (en) * 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
DE19927412A1 (de) * 1999-06-16 2000-12-21 Bayer Ag Verfahren zur Enantiomerenanreicherung von cis-8-Benzyl-7,9-dioxo-2,8-diazabicyclo [4.3.0]nonan
DE19931115A1 (de) * 1999-07-06 2001-01-11 Bayer Ag Racemisierung von R, S-Dioxo-Benzylpyrrolopiperidin
AU2001261748A1 (en) * 2000-05-19 2001-12-03 Alcon Laboratories Inc. Antibiotic compositions for treatment of the eye, ear and nose
EP2495245A3 (en) * 2004-06-10 2012-12-19 FOB Synthesis, Inc. Gram-positive carbapenem antibacterials and processes for their preparation
CN1325494C (zh) * 2005-08-18 2007-07-11 中国药科大学 3－位取代的萘啶酮类化合物及其制备方法和在制药中的应用
WO2007110835A2 (en) 2006-03-28 2007-10-04 The Procter & Gamble Company A coupling process for preparing quinolone intermediates
MY148393A (en) 2006-03-28 2013-04-15 Taigen Biotechnology Co Ltd Malate salts, and polymorphs of (3s, 5s)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
US7692015B2 (en) * 2007-01-05 2010-04-06 Zheqing Wang Economical process for preparing (S, S)-2, 8-diazabicyclo[4.3.0]nonane and its enantiomer
FR2928150A1 (fr) * 2008-02-29 2009-09-04 Vetoquinol Sa Sa Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens
EP2145891A1 (en) * 2008-07-09 2010-01-20 Vetoquinol S.A. 9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials
EP2154137A1 (en) 2008-08-04 2010-02-17 Chemo Ibérica, S.A. Crystalline form of moxifloxacin base
IT1393337B1 (it) 2009-03-06 2012-04-20 Italiana Sint Spa Sintesi di (4as, 7as)-ottaidro-1h-pirrolo[3,4-b]piridina
MX2011012134A (es) 2009-05-15 2012-02-08 Redx Pharma Ltd Derivados de farmaco de oxido-reduccion.
CA2802529C (en) 2010-06-18 2019-10-29 Woo-Baeg Choi Carbapenem antibacterials with gram-negative activity
CN102952130B (zh) * 2011-08-24 2016-03-23 重庆华邦胜凯制药有限公司 手性合成(s,s)-2,8-二氮杂双环壬烷的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT49889A (en) * 1988-03-31 1989-11-28 Hoffmann La Roche Process for producing acyl derivatives
CS273349B2 (en) * 1988-03-31 1991-03-12 Hoffmann La Roche Method of cephalosporin's new derivatives production
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
EP0997466A1 (en) * 1988-10-24 2000-05-03 PROCTER & GAMBLE PHARMACEUTICALS, INC. Novel antimicrobial lactam-quinolones
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
JPH03188080A (ja) * 1989-12-15 1991-08-16 Banyu Pharmaceut Co Ltd ピリドンカルボン酸誘導体
ZA912279B (en) * 1990-04-09 1992-02-26 Hoffmann La Roche Carbapenem compounds
EP0492277A3 (en) * 1990-12-20 1992-10-14 F. Hoffmann-La Roche Ag Cephalosporin derivatives

Also Published As

Publication number Publication date
NO933393L (no) 1994-04-11
NZ248871A (en) 1995-12-21
KR940009193A (ko) 1994-05-20
FI934411L (fi) 1994-04-10
IL107188A0 (en) 1994-01-25
PL300628A1 (en) 1994-05-16
NO933393D0 (no) 1993-09-23
FI934411A7 (fi) 1994-04-10
US5480879A (en) 1996-01-02
ZA937474B (en) 1994-04-26
AU666772B2 (en) 1996-02-22
DE4234078A1 (de) 1994-04-14
SK109293A3 (en) 1994-09-07
TW288018B (es) 1996-10-11
HUT66376A (en) 1994-11-28
FI934411A0 (fi) 1993-10-07
CN1090285A (zh) 1994-08-03
CZ9302001A3 (en) 1994-04-13
CA2107812A1 (en) 1994-04-10
EP0591808A1 (de) 1994-04-13
HU9302843D0 (en) 1993-12-28
JPH0820587A (ja) 1996-01-23
AU4864493A (en) 1994-04-21

Similar Documents

Publication Publication Date Title
MX9306023A (es) Acidos quinoloncarboxilicos y procedimiento para su obtencion.
MX9207604A (es) Derivados del acido quinolon-carboxilico y del acido naftiridon-carboxilico y procedimiento para su fabricacion.
MX9205573A (es) Nuevas 9-amino-7-(amino substituido)-6-desmetil-6-desoxitetraciclinas, metodo para su produccion y composicion farmaceutica que las contiene
MX9205532A (es) Nuevas 7-sustituidas-9-amino sustituidas 6-desmetil-6-desoxitetraciclinas, metodo para su producciony composicion farmaceutica que las contiene.
MX9206450A (es) Proceso para la produccion de isoleucina-l.
ES2109731T3 (es) Procedimiento para producir acidos n-amino-1-hidroxi-alquiliden-1,1-bisfosfonicos.
ES2196054T3 (es) Derivados de acido fenilacetico, procedimiento y productos intermedios para su obtencion y agentes que contienen los mismos.
MX9400341A (es) Derivados de los acidos quinolon- y naftiridon-carboxilicos, procedimiento para su obtencion y agentes antibacterianos y aditivos para piensos que los contienen.
MX9301129A (es) Nuevas ciclosporinas y composiciones farmaceuticas que las contienen.
MX9302461A (es) Benzo-y piridopiridonas sustituidas por sulfonilbencilo, procedimiento para su obtencion y medicamentos que las contienen.
MX9204110A (es) Derivados del acido quinolonacarboxilico y procedimiento para su preparacion.
ECSP930981A (es) Derivados de benzotiazol que tengan un substituto de difluorobuteniltio
IT1164821B (it) Benzammidi eterocicliche sostituite procedimento per la loro produzione e loro impiego come modificatori di comportamento
MX9304399A (es) Proceso novedoso para preparar [[2-bromoetil)-amino]metil]-2-nitro-1h-imidazol-1-etanol quiral y compuestos relacionados.
GT199900011A (es) Nuevos derivados del acido dihidroxihexanoico
BR8108346A (pt) Processo para preparacao enzimatica de acido l-2-amino-4-metil-fosfinobutirico
SV1995000012A (es) Acidos 5-vinil- y 5-etinil-quinolon- y-naftiridon-carboxilicos,ref. lea 30239-sv.
PT99411A (pt) Processo para a preparacao de novos carboxilatos de 2-sacarinilmetil arilo utilizados como inibidores da enzima proteolitica
MX9305093A (es) Nuevos derivadosindano-2 mercaptoacetilamina triciclicos 2-sustituidos, utiles como inhibidores de la encefalinasa.
ES2156917T3 (es) Proceso para la preparacion de derivados de 1-(4,5-dihidro-2-tiazolil)-3-azetidina-tiol.
ES2167721T3 (es) Utilizacion de 1-hidroxi-2-piridonas para el tratamiento de la dermatitis seborreica.
ES2086442T3 (es) Derivados de fluoroetilcamptotecina.
IT7826978A0 (it) Procedimento per la produzione di idrocarburi aromatici ad elevata purezza.
ES489184A0 (es) Procedimiento para la produccion de derivados de feobromina.
ES2068497T3 (es) Derivados de urea, su produccion, y composiciones farmaceuticas que los contienen.