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MX9204190A - DERIVATIVES OF 2- (4-HYDROXIPIPERIDINE) -1-ALCANOL AS ANTI-ISCHEMICAL AGENTS. - Google Patents

DERIVATIVES OF 2- (4-HYDROXIPIPERIDINE) -1-ALCANOL AS ANTI-ISCHEMICAL AGENTS.

Info

Publication number
MX9204190A
MX9204190A MX9204190A MX9204190A MX9204190A MX 9204190 A MX9204190 A MX 9204190A MX 9204190 A MX9204190 A MX 9204190A MX 9204190 A MX9204190 A MX 9204190A MX 9204190 A MX9204190 A MX 9204190A
Authority
MX
Mexico
Prior art keywords
hydroxipiperidine
alcanol
ischemical
derivatives
agents
Prior art date
Application number
MX9204190A
Other languages
Spanish (es)
Inventor
Willard Mckowan Welch Jr
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX9204190A publication Critical patent/MX9204190A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
MX9204190A 1991-07-17 1992-07-16 DERIVATIVES OF 2- (4-HYDROXIPIPERIDINE) -1-ALCANOL AS ANTI-ISCHEMICAL AGENTS. MX9204190A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73157791A 1991-07-17 1991-07-17

Publications (1)

Publication Number Publication Date
MX9204190A true MX9204190A (en) 1993-01-01

Family

ID=24940103

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9204190A MX9204190A (en) 1991-07-17 1992-07-16 DERIVATIVES OF 2- (4-HYDROXIPIPERIDINE) -1-ALCANOL AS ANTI-ISCHEMICAL AGENTS.

Country Status (22)

Country Link
EP (1) EP0594729A1 (en)
JP (1) JP2571904B2 (en)
KR (1) KR0165003B1 (en)
CN (1) CN1043759C (en)
AU (1) AU655840B2 (en)
BR (1) BR9206272A (en)
CA (1) CA2113568A1 (en)
CZ (1) CZ284133B6 (en)
EG (1) EG20048A (en)
FI (2) FI981956A7 (en)
HU (1) HUT70528A (en)
IE (1) IE922311A1 (en)
IL (1) IL102473A (en)
MX (1) MX9204190A (en)
NO (1) NO180445C (en)
NZ (1) NZ243580A (en)
PL (1) PL169884B1 (en)
PT (1) PT100689B (en)
RU (1) RU2065859C1 (en)
TW (1) TW201732B (en)
WO (1) WO1993002052A1 (en)
ZA (1) ZA925306B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
PL173618B1 (en) * 1992-10-30 1998-04-30 Pfizer Neuroprotective 3,4-dihydro-2(1h)-quinolonic compounds
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
US6978166B2 (en) 1994-10-07 2005-12-20 Saint Louis University System for use in displaying images of a body part
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610736B (en) * 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
CA2220649C (en) * 1996-12-03 2007-02-13 F. Hoffmann-La Roche Ag 4-hydroxy-piperidine derivatives
AU3676100A (en) * 1999-04-09 2000-11-14 Mochida Pharmaceutical Co., Ltd. Remedies for neuropathic pain
TWI254043B (en) * 1999-06-08 2006-05-01 Hoffmann La Roche Ethanesulfonyl-piperidine derivatives having good affinity to N-methyl-D-aspartate (NMDA) receptor
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
US6495561B2 (en) 1999-10-29 2002-12-17 Merck & Co., Inc. 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
US6432976B1 (en) 1999-10-29 2002-08-13 Merck & Co., Inc. 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
US6380205B1 (en) 1999-10-29 2002-04-30 Merck & Co., Inc. 2-cyclohexyl quinazoline NMDA/NR2B antagonists
US6291499B1 (en) 1999-10-29 2001-09-18 Merck & Co., Inc. 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
US6362196B1 (en) 1999-10-29 2002-03-26 Merck & Co., Inc. Method to treat pain utilizing benzimidazole NMDA/NR2B antagonists
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
US6489477B1 (en) 1999-10-29 2002-12-03 Merck & Co., Inc. 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists
US6316474B1 (en) 1999-10-29 2001-11-13 Merck & Co., Inc. 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
NZ527365A (en) 2001-02-23 2005-08-26 Merck & Co Inc N-substituted nonaryl-heterocyclic NMDA/NR2B antagonists
US7259157B2 (en) 2001-04-03 2007-08-21 Merck & Co., Inc. N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B Antagonists
JP4544999B2 (en) 2002-11-25 2010-09-15 持田製薬株式会社 Respiratory disease therapeutic agent comprising 4-hydroxypiperidine derivative as active ingredient
BRPI0415113A (en) * 2003-10-08 2006-11-28 Pfizer condensed lactam compounds
TWI409289B (en) 2010-09-02 2013-09-21 Taiwan Union Technology Corp Stable solution of the polymer prepared from n,o-heterocycles and its preparinging method and use
EP4168116A4 (en) * 2020-06-23 2024-07-10 Biohaven Therapeutics Ltd. TOPICAL FORMULATIONS OF (1S)-1-PHENYL-2-PYRIDIN-2-YLETHANAMINE

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
FR2546166B1 (en) * 1983-05-19 1985-10-25 Synthelabo ENANTIOMERS OF ERYTHRO (BENZYL-4 PIPERIDINO) -2 (HYDROXY-4 OR BENZYLOXY-4 PHENYL) -1 PROPANOL, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2640266B2 (en) * 1988-07-12 1992-07-10 Synthelabo INDOLONES-2, QUINOLEINONES-2, BENZO (B) AZEPINONES-2 AND BENZIMIDAZOLONES-2 DERIVATIVES OF (HYDROXY-1 PIPERIDINYL-2 ALKYL), THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
ES2098248T3 (en) * 1989-05-17 1997-05-01 Pfizer DERIVATIVES OF 2-PIPERIDINE-1-ALCANOLS AS ANTI-ISCHEMICAL AGENTS.
US5306723A (en) * 1990-05-10 1994-04-26 Pfizer Inc. Neuroprotective indolone and related derivatives

Also Published As

Publication number Publication date
ZA925306B (en) 1994-01-17
FI940192A7 (en) 1994-01-14
FI981956L (en) 1998-09-11
NO180445B (en) 1997-01-13
NO940144L (en) 1994-01-14
AU655840B2 (en) 1995-01-12
CN1068566A (en) 1993-02-03
RU2065859C1 (en) 1996-08-27
TW201732B (en) 1993-03-11
IL102473A0 (en) 1993-01-14
EP0594729A1 (en) 1994-05-04
HUT70528A (en) 1995-10-30
JPH06504293A (en) 1994-05-19
CN1043759C (en) 1999-06-23
NZ243580A (en) 1994-10-26
PL169884B1 (en) 1996-09-30
CA2113568A1 (en) 1993-02-04
NO940144D0 (en) 1994-01-14
PT100689B (en) 1999-06-30
FI981956A0 (en) 1998-09-11
JP2571904B2 (en) 1997-01-16
BR9206272A (en) 1995-04-11
KR0165003B1 (en) 1999-01-15
NO180445C (en) 1997-04-23
CZ400892A3 (en) 1994-03-16
IL102473A (en) 1997-07-13
HU9400136D0 (en) 1994-05-30
PT100689A (en) 1993-10-29
FI981956A7 (en) 1998-09-11
FI940192A0 (en) 1994-01-14
FI940192L (en) 1994-01-14
WO1993002052A1 (en) 1993-02-04
AU2322592A (en) 1993-02-23
CZ284133B6 (en) 1998-08-12
IE922311A1 (en) 1993-01-27
EG20048A (en) 1997-03-27

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