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MX9203763A - Polipeptidos terapeuticos a base del factor de von willebrand - Google Patents

Polipeptidos terapeuticos a base del factor de von willebrand

Info

Publication number
MX9203763A
MX9203763A MX9203763A MX9203763A MX9203763A MX 9203763 A MX9203763 A MX 9203763A MX 9203763 A MX9203763 A MX 9203763A MX 9203763 A MX9203763 A MX 9203763A MX 9203763 A MX9203763 A MX 9203763A
Authority
MX
Mexico
Prior art keywords
von willebrand
willebrand factor
therapeutic polypeptides
polypeptides based
therapeutic
Prior art date
Application number
MX9203763A
Other languages
English (en)
Inventor
Michael N Chang
Daniel G Mcgarry
John R Regan
Zaverio M Ruggeri
Jerry L Ware
Original Assignee
Rhone Poulenc Rorer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Int filed Critical Rhone Poulenc Rorer Int
Publication of MX9203763A publication Critical patent/MX9203763A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Un polipéptido como patrón sobre un fragmento de subunidad de factor de von Willebrand (vWF) madura, de tipo salvaje, que tiene uno o más sitios de unión o afinidad predeterminada para uno o más de los ligandos del grupo que consiste de colágeno.
MX9203763A 1991-06-28 1992-06-29 Polipeptidos terapeuticos a base del factor de von willebrand MX9203763A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72058891A 1991-06-28 1991-06-28

Publications (1)

Publication Number Publication Date
MX9203763A true MX9203763A (es) 1993-08-01

Family

ID=24894560

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9203763A MX9203763A (es) 1991-06-28 1992-06-29 Polipeptidos terapeuticos a base del factor de von willebrand

Country Status (3)

Country Link
AU (1) AU2297792A (es)
MX (1) MX9203763A (es)
WO (1) WO1993000357A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5900476A (en) * 1986-05-30 1999-05-04 The Scripps Research Institute Therapeutic domains of van Willebrand factor
EP0648268A1 (en) * 1991-03-27 1995-04-19 The Scripps Research Institute Therapeutic fragments of von willebrand factor
FR2686901A1 (fr) * 1992-01-31 1993-08-06 Rhone Poulenc Rorer Sa Nouveaux polypeptides antithrombotiques, leur preparation et compositions pharmaceutiques les contenant.
ZA942818B (en) * 1993-04-23 1995-01-30 Bio Technology General Corp Method of enhancing thrombolysis.
US5709180A (en) * 1997-02-06 1998-01-20 General Motors Corporation Narrow cam two-step lifter
US7349393B2 (en) * 1999-12-02 2008-03-25 Verizon Business Global Llc Method and system for implementing an improved universal packet switching capability in a data switch
BRPI0519562A2 (pt) * 2004-12-27 2009-01-27 Baxter Int construÇço proteinÁcea, complexo, mÉtodo para prolongar a meia-vida in vivo de fator viii (fviii) ou um derivado biologicamente ativo do mesmo composiÇço farmacÊutica, e, mÉtodo para formar uma construÇço proteinÁcea
NZ572050A (en) 2006-03-31 2011-09-30 Baxter Int Factor VIII conjugated to polyethylene glycol
US7645860B2 (en) 2006-03-31 2010-01-12 Baxter Healthcare S.A. Factor VIII polymer conjugates

Also Published As

Publication number Publication date
AU2297792A (en) 1993-01-25
WO1993000357A1 (en) 1993-01-07

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