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MX7668A - Nuevos compuestos farmaceuticos y procedimiento para obtenerlos - Google Patents

Nuevos compuestos farmaceuticos y procedimiento para obtenerlos

Info

Publication number
MX7668A
MX7668A MX766887A MX766887A MX7668A MX 7668 A MX7668 A MX 7668A MX 766887 A MX766887 A MX 766887A MX 766887 A MX766887 A MX 766887A MX 7668 A MX7668 A MX 7668A
Authority
MX
Mexico
Prior art keywords
procedure
obtaining
pharmaceutical compounds
new pharmaceutical
new
Prior art date
Application number
MX766887A
Other languages
English (en)
Other versions
MX174371B (es
Inventor
Peter Thaddeus Gallagher
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of MX7668A publication Critical patent/MX7668A/es
Publication of MX174371B publication Critical patent/MX174371B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14Nitrogen atoms
    • C07D261/16Benzene-sulfonamido isoxazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
MX007668A 1986-08-08 1987-08-06 Nuevos compuestos farmaceuticos y procedimiento para obtenerlos MX174371B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868619432A GB8619432D0 (en) 1986-08-08 1986-08-08 Pharmaceutical compounds

Publications (2)

Publication Number Publication Date
MX7668A true MX7668A (es) 1993-08-01
MX174371B MX174371B (es) 1994-05-11

Family

ID=10602473

Family Applications (1)

Application Number Title Priority Date Filing Date
MX007668A MX174371B (es) 1986-08-08 1987-08-06 Nuevos compuestos farmaceuticos y procedimiento para obtenerlos

Country Status (23)

Country Link
US (1) US4892963A (es)
EP (1) EP0257882B1 (es)
JP (1) JPS63239259A (es)
KR (2) KR880002823A (es)
CN (1) CN1015256B (es)
AR (2) AR244660A1 (es)
AT (1) ATE65494T1 (es)
AU (1) AU604737B2 (es)
CA (1) CA1317964C (es)
DE (1) DE3771611D1 (es)
DK (1) DK169404B1 (es)
EG (1) EG18269A (es)
ES (1) ES2031510T3 (es)
GB (1) GB8619432D0 (es)
GR (1) GR3002714T3 (es)
HU (1) HU197559B (es)
IL (1) IL83432A (es)
MX (1) MX174371B (es)
NZ (1) NZ221352A (es)
PH (1) PH22821A (es)
PT (1) PT85476B (es)
RU (1) RU1771472C (es)
ZA (1) ZA875813B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268382A (en) * 1985-09-27 1993-12-07 Hoechst Aktiengesellschaft Medicaments to combat autoimmune diseases, in particular systemic lupus erythematosus
DE3534440A1 (de) * 1985-09-27 1987-04-02 Hoechst Ag Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes
US4975462A (en) * 1988-07-29 1990-12-04 Bristol-Myers Company Antiarthritic α-arylcarbamoyl cyanoacetic acid derivatives
US5583150A (en) * 1989-08-18 1996-12-10 Alcon Laboratories, Inc. 5-methyl-isoxazole-4-carboxylic acid anilides and 2-hydroxyethylidene-cyano acetic anilides for the treatment of ocular diseases
DD297328A5 (de) * 1989-08-18 1992-01-09 �������@���������k���Kk�� 5-methyl-isoxalol-4-carbonsaeureanilide und 2 hydroxyethyliden-cyanoessigsaeureanilide zur behandlung von augenerkrankungen
US5108999A (en) * 1990-02-02 1992-04-28 Syntex (U.S.A.) Inc. 4-isoxazolecarboxamide derivatives
US5001124A (en) * 1990-02-02 1991-03-19 Syntex (U.S.A.) Inc. 4-isoxazolecarboxamide derivatives
JPH04211048A (ja) * 1990-03-05 1992-08-03 Mitsubishi Kasei Corp チオカルバモイルアセトニトリル誘導体
HU222234B1 (hu) * 1990-05-18 2003-05-28 Aventis Pharma Deutschland Gmbh. Eljárás izoxazol-4-karbonsav-amidok és hidroxi-alkilidén-cián-ecetsav-amidok, a vegyületeket tartalmazó gyógyászati készítmények és az ismert vegyületeket tartalmazó rákellenes hatású gyógyszerkészítmények előállítására
IL102790A (en) * 1991-09-17 1996-01-31 Roussel Uclaf 3-Cycloalkyl-prop-2- enamide derivatives
ATE128353T1 (de) * 1991-10-23 1995-10-15 Hoechst Ag N-phenyl-2-cyano-3-hydroxycrotonsäureamidderiva e und deren verwendung als arzneimittel mit immunmodulatorischer eigenschaft.
GB9200275D0 (en) * 1992-01-08 1992-02-26 Roussel Lab Ltd Chemical compounds
TW314467B (es) * 1993-03-31 1997-09-01 Hoechst Ag
WO1994024095A1 (en) * 1993-04-16 1994-10-27 Abbott Laboratories Immunosuppressive agents
GB9320299D0 (en) * 1993-10-01 1993-11-17 Roussel Lab Ltd Isoxazole derivatives
ES2148561T3 (es) * 1994-10-17 2000-10-16 Aventis Pharma Ltd Prevencion y curacion de enfermedades alergicas de tipo i.
DE19702988A1 (de) 1997-01-28 1998-07-30 Hoechst Ag Isoxazol- und Crotonsäureamidderivate und deren Verwendung als Arzneimittel und Diagnostika
HRP20050176A2 (en) * 1999-12-16 2005-08-31 Teva Pharmaceutical Industries Ltd. Novel processes for making - and a new crystalline form of-leflunomide
YU61602A (sh) * 2000-02-15 2006-01-16 Teva Pharmaceutical Industries Ltd. Postupak za dobijanje leflunomida
DE10311763A1 (de) * 2003-03-18 2004-10-07 Aventis Pharma Deutschland Gmbh Verfahren zur Herstellung von 2-Cyan-3-hydroxy-N-(phenyl)but-2-enamiden
US6894184B2 (en) 2003-03-18 2005-05-17 Aventis Pharma Deutschland Gmbh Process for preparing 2-cyano-3-hydroxy-N-(phenyl)but-2-enamides
US20160287549A1 (en) 2013-11-22 2016-10-06 Genzyme Corporation Novel methods for treating neurodegenerative diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL186239B (nl) * 1975-06-05 Hoechst Ag Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze.
DK545976A (da) * 1975-12-11 1977-06-12 Hoechst Ag Cyaneddikesyreanilidderivater fremgangsmade til deres fremstilling og midler der indeholder disse forbindelser
DE2654797A1 (de) * 1976-12-03 1978-06-08 Hoechst Ag Verfahren zur herstellung von isoxazolderivaten
DE2655009A1 (de) * 1976-12-04 1978-06-15 Hoechst Ag Isoxazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
EP0143142A3 (de) * 1979-06-11 1985-07-17 Ciba-Geigy Ag Alphacarbamoyl-pyrrolpropionitrile, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend diese Verbindungen, sowie ihre therapeutische Verwendung

Also Published As

Publication number Publication date
DK413987A (da) 1988-02-09
CA1317964C (en) 1993-05-18
RU1771472C (ru) 1992-10-23
PT85476A (en) 1987-09-01
CN1015256B (zh) 1992-01-01
HU197559B (en) 1989-04-28
GR3002714T3 (en) 1993-01-25
DE3771611D1 (de) 1991-08-29
DK169404B1 (da) 1994-10-24
KR880002815A (ko) 1988-05-11
EP0257882B1 (en) 1991-07-24
EP0257882A1 (en) 1988-03-02
HUT44523A (en) 1988-03-28
AR244660A1 (es) 1993-11-30
NZ221352A (en) 1989-10-27
KR880002823A (ko) 1988-05-11
JPS63239259A (ja) 1988-10-05
US4892963A (en) 1990-01-09
MX174371B (es) 1994-05-11
AR247876A1 (es) 1995-04-28
ES2031510T3 (es) 1992-12-16
EG18269A (en) 1992-12-30
GB8619432D0 (en) 1986-09-17
DK413987D0 (da) 1987-08-07
IL83432A (en) 1992-06-21
AU7668187A (en) 1988-02-11
IL83432A0 (en) 1988-01-31
ZA875813B (en) 1989-04-26
PT85476B (pt) 1990-06-29
ATE65494T1 (de) 1991-08-15
CN87105516A (zh) 1988-02-24
PH22821A (en) 1989-01-19
AU604737B2 (en) 1991-01-03

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