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MX217111B - Una cepa de e. coli mutante con produccion incrementada de acido succinico - Google Patents

Una cepa de e. coli mutante con produccion incrementada de acido succinico

Info

Publication number
MX217111B
MX217111B MX9804338A MX9804338A MX217111B MX 217111 B MX217111 B MX 217111B MX 9804338 A MX9804338 A MX 9804338A MX 9804338 A MX9804338 A MX 9804338A MX 217111 B MX217111 B MX 217111B
Authority
MX
Mexico
Prior art keywords
strain
succinic acid
acid production
increased succinic
mutant
Prior art date
Application number
MX9804338A
Other languages
English (en)
Other versions
MX9804338A (es
Inventor
Lucy Stols
Mark Donnelly
Cynthia S Millard
Original Assignee
Univ Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Chicago filed Critical Univ Chicago
Publication of MX9804338A publication Critical patent/MX9804338A/es
Publication of MX217111B publication Critical patent/MX217111B/es

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12Unicellular algae; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • C12P7/46Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MX9804338A 1995-11-02 1996-10-31 Una cepa de e. coli mutante con produccion incrementada de acido succinico MX217111B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/556,805 US5770435A (en) 1995-11-02 1995-11-02 Mutant E. coli strain with increased succinic acid production
PCT/US1996/017661 WO1997016528A1 (en) 1995-11-02 1996-10-31 A mutant e. coli strain with increased succinic acid production

Publications (2)

Publication Number Publication Date
MX9804338A MX9804338A (es) 1999-05-31
MX217111B true MX217111B (es) 2003-10-23

Family

ID=24222932

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9804338A MX217111B (es) 1995-11-02 1996-10-31 Una cepa de e. coli mutante con produccion incrementada de acido succinico

Country Status (11)

Country Link
US (2) US5770435A (es)
EP (1) EP0953037A4 (es)
JP (1) JP2000500333A (es)
KR (1) KR19990067095A (es)
CN (1) CN1097632C (es)
AU (1) AU724822B2 (es)
BR (1) BR9611220A (es)
CA (1) CA2236472C (es)
HU (1) HUP9901992A3 (es)
MX (1) MX217111B (es)
WO (1) WO1997016528A1 (es)

Families Citing this family (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR19990013007A (ko) * 1997-07-31 1999-02-25 박원훈 형질전환된 대장균 ss373(kctc 8818p)과 이를 이용한숙신산의 생산방법
US7393632B2 (en) 1999-12-10 2008-07-01 Invitrogen Corp. Use of multiple recombination sites with unique specificity in recombinational cloning
HUP0201204A3 (en) 1999-05-21 2004-07-28 Cargill Dow Llc Minnetonka Methods and materials for synthesis of organic products
US6287480B1 (en) * 2000-01-11 2001-09-11 Applied Carbochemicals, Inc. Deicing compositions and methods of use
US6743610B2 (en) 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates
JP4469568B2 (ja) * 2003-07-09 2010-05-26 三菱化学株式会社 有機酸の製造方法
DK1647594T3 (da) * 2003-07-29 2010-05-25 Res Inst Innovative Tech Earth Koryneform bakteriel transformant og fremgangsmåde til fremstilling af dicarboxylsyre under anvendelse af denne
US7163812B2 (en) * 2003-08-06 2007-01-16 Board Of Trustees Of Michigan State University Actinobacillus succinogenes shuttle vector and methods of use
JP4575086B2 (ja) * 2003-08-28 2010-11-04 三菱化学株式会社 コハク酸の製造方法
WO2005021770A1 (ja) * 2003-08-28 2005-03-10 Mitsubishi Chemical Corporation コハク酸の製造方法
CN1852978A (zh) * 2003-09-17 2006-10-25 三菱化学株式会社 制备无-氨基有机酸的方法
CN101654666B (zh) * 2003-09-30 2012-11-14 三井化学株式会社 用于生产d-乳酸的生物催化剂
BRPI0414764B8 (pt) * 2003-09-30 2018-09-18 Ajinomoto Kk método para purificar ácido succínico à partir de caldo de fermentação
CA2545363C (en) * 2003-11-27 2011-11-15 Korea Advanced Institute Of Science And Technology Rumen bacteria mutants and process for producing succinic acid employing the same
KR100556099B1 (ko) * 2003-11-27 2006-03-03 한국과학기술원 루멘 박테리아 변이균주 및 이를 이용한 숙신산의 제조방법
US6846431B1 (en) 2003-12-26 2005-01-25 Diversified Natural Products, Inc. Environmentally benign, non-toxic, non-corrosive engine coolant/antifreeze
JP5023701B2 (ja) * 2004-05-20 2012-09-12 味の素株式会社 コハク酸生産菌及びコハク酸の製造方法
EP1748062B1 (en) * 2004-05-20 2012-06-13 Ajinomoto Co., Inc. Succinic acid-producing bacterium and process for producing succinic acid
WO2006031424A2 (en) * 2004-08-27 2006-03-23 Rice University Mutant e. coli strain with increased succinic acid production
EP3925997B1 (en) 2005-04-22 2024-07-17 Mitsubishi Chemical Corporation Biomass-resource-derived polyester and production process thereof
JP4380653B2 (ja) * 2005-04-22 2009-12-09 三菱化学株式会社 ポリエステル及びその製造方法
JP4380654B2 (ja) * 2005-04-22 2009-12-09 三菱化学株式会社 ポリエステル及びその製造方法
JP2006328377A (ja) * 2005-04-26 2006-12-07 Mitsubishi Chemicals Corp ポリエステルペレットの貯蔵方法
JP4760121B2 (ja) * 2005-05-17 2011-08-31 三菱化学株式会社 コハク酸の製造方法
KR100727054B1 (ko) * 2005-08-19 2007-06-12 한국과학기술원 푸마레이트 하이드라타제 c를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법
KR100676160B1 (ko) * 2005-08-19 2007-02-01 한국과학기술원 말릭효소를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법
KR100679638B1 (ko) * 2005-08-19 2007-02-06 한국과학기술원 포메이트 디하이드로게나제 d 또는 e를 코딩하는 유전자로 형질전환된 미생물 및 이를 이용한 숙신산의 제조방법
US20070111294A1 (en) * 2005-09-09 2007-05-17 Genomatica, Inc. Methods and organisms for the growth-coupled production of succinate
EP1947190B1 (en) * 2005-10-18 2017-11-29 Ajinomoto Co., Inc. Process for production of succinic acid
WO2007046767A1 (en) * 2005-10-20 2007-04-26 Kris Arvid Berglund Process for the production of succinic acid
US7335066B2 (en) * 2005-12-16 2008-02-26 James A. Carroll Network connector and connection system
CN100432215C (zh) * 2006-01-24 2008-11-12 江南大学 一种微生物发酵生产丁二酸的菌种和方法
US7993888B2 (en) * 2006-02-24 2011-08-09 Mitsubishi Chemical Corporation Bacterium having enhanced 2-oxoglutarate dehydrogenase activity
KR100762962B1 (ko) * 2006-05-04 2007-10-04 한국과학기술원 게놈정보 및 인실리코 분석을 이용한 배양배지의 제조방법
KR100780324B1 (ko) 2006-07-28 2007-11-29 한국과학기술원 신규 순수 숙신산 생성 변이 미생물 및 이를 이용한 숙신산제조방법
CN101029316B (zh) * 2006-12-13 2010-06-09 华东理工大学 大肠杆菌生产琥珀酸的方法
WO2008091627A2 (en) * 2007-01-22 2008-07-31 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
US8067214B2 (en) 2007-03-16 2011-11-29 Genomatica, Inc. Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors
EP2149608A4 (en) 2007-04-16 2013-02-20 Ajinomoto Kk PROCESS FOR PREPARING AN ORGANIC ACID
EP2147970B1 (en) 2007-04-17 2014-12-31 Ajinomoto Co., Inc. A method for producing an acidic substance having a carboxyl group
MX298012B (es) 2007-07-06 2012-11-04 Basf Se Metodo para la produccion de una solucion de glucosa acuosa a partir de maiz.
EP2188243A2 (en) * 2007-08-10 2010-05-26 Genomatica, Inc. Methods for the synthesis of acrylic acid and derivatives from fumaric acid
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
CN101381740B (zh) * 2007-09-05 2011-09-07 中国科学院过程工程研究所 用于生产琥珀酸的重组质粒、基因工程菌、其制法及用途
WO2009072562A1 (ja) 2007-12-06 2009-06-11 Ajinomoto Co., Inc. 有機酸の製造方法
WO2009075303A1 (ja) 2007-12-12 2009-06-18 Mitsubishi Chemical Corporation 脂肪族ポリエステル樹脂及びその製造方法
US7803589B2 (en) 2008-01-22 2010-09-28 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
US7977084B2 (en) 2008-03-05 2011-07-12 Genomatica, Inc. Primary alcohol producing organisms
CN102066551B (zh) * 2008-03-27 2013-10-09 基因组股份公司 用于产生己二酸和其他化合物的微生物
EP2285973A4 (en) 2008-05-01 2012-04-25 Genomatica Inc PROCESS FOR PREPARING METHACRYLIC ACID
US8129154B2 (en) * 2008-06-17 2012-03-06 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
US20100021978A1 (en) * 2008-07-23 2010-01-28 Genomatica, Inc. Methods and organisms for production of 3-hydroxypropionic acid
WO2010030711A2 (en) 2008-09-10 2010-03-18 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
JP5881135B2 (ja) 2008-09-30 2016-03-09 東レ株式会社 化学品の製造方法および連続培養装置
US20100184173A1 (en) * 2008-11-14 2010-07-22 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
WO2010071697A1 (en) * 2008-12-16 2010-06-24 Genomatica, Inc. Microorganisms and methods for conversion of syngas and other carbon sources to useful products
JP2012525156A (ja) 2009-04-30 2012-10-22 ゲノマチカ, インク. イソプロパノール、n−ブタノール、及びイソブタノールの産生のための微生物
MY176050A (en) * 2009-04-30 2020-07-22 Genomatica Inc Organisms for the production of 1,3-butanediol
KR102036265B1 (ko) 2009-05-07 2019-10-24 게노마티카 인코포레이티드 아디페이트, 헥사메틸렌디아민 및 6-아미노카프로산의 생합성을 위한 미생물 및 방법
AU2010248831A1 (en) * 2009-05-15 2011-11-24 Genomatica, Inc. Organisms for the production of cyclohexanone
KR20120038433A (ko) * 2009-06-04 2012-04-23 게노마티카 인코포레이티드 발효액 성분들의 분리 방법
CN107384846B (zh) 2009-06-04 2021-08-10 基因组股份公司 生产1,4-丁二醇的微生物和相关方法
WO2010144746A2 (en) * 2009-06-10 2010-12-16 Genomatica, Inc. Microorganisms and methods for carbon-efficient biosynthesis of mek and 2-butanol
EP2462221B1 (en) 2009-08-05 2017-02-22 Genomatica, Inc. Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
CN107586753A (zh) 2009-09-09 2018-01-16 基因组股份公司 协同产生异丙醇与伯醇,二元醇和酸的微生物和方法
CN102762735B (zh) 2009-10-13 2016-08-03 基因组股份公司 生产1,4-丁二醇、4-羟基丁醛、4-羟基丁酰-coa、腐胺和相关化合物的微生物及其相关方法
BR112012009332A2 (pt) 2009-10-23 2015-09-15 Genomatica Inc micro-organismo para a produção de anilina
US8530210B2 (en) * 2009-11-25 2013-09-10 Genomatica, Inc. Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
SG181607A1 (en) 2009-12-10 2012-07-30 Genomatica Inc Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol
CN102781900A (zh) 2009-12-31 2012-11-14 麦兰特公司 从含有琥珀酸铵的发酵液纯化琥珀酸
SG182686A1 (en) 2010-01-29 2012-08-30 Genomatica Inc Microorganisms and methods for the biosynthesis of p-toluate and terephthalate
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US8445244B2 (en) 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
CA2797409C (en) 2010-05-05 2019-12-24 Genomatica, Inc. Microorganisms and methods for the biosynthesis of butadiene
JP2013535203A (ja) 2010-07-26 2013-09-12 ジェノマティカ・インコーポレイテッド 芳香族、2,4−ペンタジエノエートおよび1,3−ブタジエンを生合成するための微生物および方法
EP2601300A1 (en) 2010-08-06 2013-06-12 Danisco US Inc. Production of isoprene under neutral ph conditions
WO2012019159A1 (en) 2010-08-06 2012-02-09 Danisco Us Inc. Neutral ph saccharification and fermentation
AU2011339328A1 (en) 2010-12-09 2013-07-04 Toray Industries, Inc. Method for producing chemical by continuous fermentation
WO2012109578A2 (en) * 2011-02-11 2012-08-16 The Trustees Of Dartmouth College Clostridium thermocellum strains for enhanced ethanol production and method of their use
CN102174458A (zh) * 2011-03-09 2011-09-07 南京工业大学 一种制备重组大肠杆菌发酵生产丁二酸的方法
WO2012125218A1 (en) 2011-03-14 2012-09-20 Dow Global Technologies Llc Processes for producing terephthalic acid and terephthalic esters
BR112013027170A2 (pt) 2011-04-29 2017-06-20 Danisco Us Inc processo em ph único para liquefação e sacarificação de amido para xaropes de glicose de densidade alta
US8951764B2 (en) 2011-08-05 2015-02-10 Danisco Us Inc. Production of isoprenoids under neutral pH conditions
WO2013166075A1 (en) 2012-04-30 2013-11-07 Woods Hole Oceanographic Institution Cobalamin acquisition protein and use thereof
BR112014030202A2 (pt) 2012-06-04 2017-09-12 Genomatica Inc microorganismos e métodos para a produção de 4-hidroxibutirato 1,4-butanodiol e compostos relacionados
KR101464656B1 (ko) * 2012-06-15 2014-12-02 한국생명공학연구원 발효산물 고생성능을 가지는 변이 미생물 및 이를 이용한 발효산물의 제조방법
US9506087B2 (en) 2012-08-07 2016-11-29 Codexis, Inc. Glucose and xylose co-utilization in E. coli
CN102864113B (zh) * 2012-10-16 2014-01-22 南京工业大学 产丁二酸的菌株及其生产丁二酸的方法和应用
KR101581504B1 (ko) * 2013-03-18 2015-12-31 지에스칼텍스 주식회사 2,3-부탄디올의 생성능이 증강된 재조합 미생물 및 이를 이용한 2,3-부탄디올의 생산 방법
JP2017216881A (ja) 2014-12-26 2017-12-14 味の素株式会社 ジカルボン酸の製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190495A (en) * 1976-09-27 1980-02-26 Research Corporation Modified microorganisms and method of preparing and using same
US5143834A (en) * 1986-06-11 1992-09-01 Glassner David A Process for the production and purification of succinic acid
US5182199A (en) * 1987-05-27 1993-01-26 Hartley Brian S Thermophilic ethanol production in a two-stage closed system
JP3043063B2 (ja) * 1989-04-27 2000-05-22 バイオコントロール システムズ インコーポレイテッド 微生物のための沈澱テスト
US5416020A (en) * 1992-09-29 1995-05-16 Bio-Technical Resources Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid
US5521075A (en) * 1994-12-19 1996-05-28 Michigan Biotechnology Institute Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants
US5573931A (en) * 1995-08-28 1996-11-12 Michigan Biotechnology Institute Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants

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WO1997016528A1 (en) 1997-05-09
MX9804338A (es) 1999-05-31
CA2236472A1 (en) 1997-05-09
HUP9901992A3 (en) 2000-04-28
EP0953037A4 (en) 2001-06-27
BR9611220A (pt) 1999-12-28
HUP9901992A2 (hu) 1999-10-28
USRE37393E1 (en) 2001-09-25
CA2236472C (en) 2012-02-07
AU724822B2 (en) 2000-09-28
CN1097632C (zh) 2003-01-01
CN1202930A (zh) 1998-12-23
JP2000500333A (ja) 2000-01-18
EP0953037A1 (en) 1999-11-03
AU7605896A (en) 1997-05-22
KR19990067095A (ko) 1999-08-16
US5770435A (en) 1998-06-23

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