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MX2025009198A - Variantes de edulcorante de trufa de miel (hts) - Google Patents

Variantes de edulcorante de trufa de miel (hts)

Info

Publication number
MX2025009198A
MX2025009198A MX2025009198A MX2025009198A MX2025009198A MX 2025009198 A MX2025009198 A MX 2025009198A MX 2025009198 A MX2025009198 A MX 2025009198A MX 2025009198 A MX2025009198 A MX 2025009198A MX 2025009198 A MX2025009198 A MX 2025009198A
Authority
MX
Mexico
Prior art keywords
hts
sweetener
protein variants
truffle
honey
Prior art date
Application number
MX2025009198A
Other languages
English (en)
Inventor
Marina Nadal
Anthony J Clark
Zheyuan Guo
Stephen A Gravina
Anthony Westgate
Bassam Alkotaini
Brendan Sharkey
Joseph Meilen
James Patrick Langan
Miles Ingwers
Daniel Edward Connors
Michael G Edwards
Ranjan Patnaik
Simaeys Karli R Van
Benjamin Jaacks
Original Assignee
Mycotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mycotechnology Inc filed Critical Mycotechnology Inc
Publication of MX2025009198A publication Critical patent/MX2025009198A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Seasonings (AREA)

Abstract

Se describen variantes de proteína modificadora de sabor dulce fúngicas (designadas variantes de proteína de edulcorante de trufa de miel (HTS)) y polinucleótidos que codifican para las variantes de proteína. Específicamente, se describen variantes de proteína Myd (HTS) con actividad de modulación de sabor dulce, y el ADNc que codifica para las mismas, junto con métodos para aislar este ADNc y para aislar y expresar las proteínas. También se divulgan composiciones edulcorantes que incluyen las proteínas de la invención, y métodos para proporcionar un sabor mejorado a un producto para administración oral.
MX2025009198A 2023-02-08 2025-08-06 Variantes de edulcorante de trufa de miel (hts) MX2025009198A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202363444185P 2023-02-08 2023-02-08
US202363524794P 2023-07-03 2023-07-03
US202363541591P 2023-09-29 2023-09-29
US202463618616P 2024-01-08 2024-01-08
PCT/US2024/015023 WO2024168164A2 (en) 2023-02-08 2024-02-08 Honey truffle sweetener (hts) variants

Publications (1)

Publication Number Publication Date
MX2025009198A true MX2025009198A (es) 2025-09-02

Family

ID=92263534

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2025009198A MX2025009198A (es) 2023-02-08 2025-08-06 Variantes de edulcorante de trufa de miel (hts)

Country Status (9)

Country Link
US (1) US20250136649A1 (es)
EP (1) EP4661692A2 (es)
KR (1) KR20250148630A (es)
CN (1) CN120659547A (es)
AU (1) AU2024218034A1 (es)
CL (1) CL2025002336A1 (es)
IL (1) IL322639A (es)
MX (1) MX2025009198A (es)
WO (1) WO2024168164A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025172491A1 (en) * 2024-02-16 2025-08-21 Givaudan Sa Compositions comprising honey truffle protein

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021298029B2 (en) * 2020-06-25 2023-08-24 Mycotechnology, Inc. Sweet protein from truffle
CN118475594A (zh) * 2021-12-30 2024-08-09 麦可科技有限公司 来自块菌的甜蛋白突变体

Also Published As

Publication number Publication date
CN120659547A (zh) 2025-09-16
CL2025002336A1 (es) 2025-09-12
EP4661692A2 (en) 2025-12-17
WO2024168164A3 (en) 2024-10-17
IL322639A (en) 2025-10-01
KR20250148630A (ko) 2025-10-14
AU2024218034A1 (en) 2025-07-17
US20250136649A1 (en) 2025-05-01
WO2024168164A2 (en) 2024-08-15

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