MX2024015072A - Anticuerpos anti-egfr/met y usos de los mismos - Google Patents
Anticuerpos anti-egfr/met y usos de los mismosInfo
- Publication number
- MX2024015072A MX2024015072A MX2024015072A MX2024015072A MX2024015072A MX 2024015072 A MX2024015072 A MX 2024015072A MX 2024015072 A MX2024015072 A MX 2024015072A MX 2024015072 A MX2024015072 A MX 2024015072A MX 2024015072 A MX2024015072 A MX 2024015072A
- Authority
- MX
- Mexico
- Prior art keywords
- egfr
- antigen
- met antibodies
- binding protein
- protein constructs
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se proporcionan construcciones de proteínas de unión a antígenos (por ejemplo, anticuerpos biespecíficos, fragmentos de unión a antígeno de los mismos o ADC), en donde las construcciones de proteína de unión a antígeno se unen específicamente a dos antígenos diferentes (por ejemplo, EGFR y MET).
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| CN2022102231 | 2022-06-29 | ||
| CN2022108838 | 2022-07-29 | ||
| CN2022116678 | 2022-09-02 | ||
| CN2022141416 | 2022-12-23 | ||
| PCT/CN2023/103811 WO2024002235A1 (en) | 2022-06-29 | 2023-06-29 | Anti-egfr/met antibodies and uses thereof |
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| MX2024015285A MX2024015285A (es) | 2022-06-29 | 2024-12-09 | Anticuerpos anti-egfr/met y usos de los mismos |
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| MX2024015285A MX2024015285A (es) | 2022-06-29 | 2024-12-09 | Anticuerpos anti-egfr/met y usos de los mismos |
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| CN (2) | CN119487075A (es) |
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| CA (2) | CA3260255A1 (es) |
| MX (2) | MX2024015072A (es) |
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| CN121194800A (zh) * | 2023-05-12 | 2025-12-23 | 百奥赛图(北京)医药科技股份有限公司 | 接头化合物和配体-药物缀合物及其制备方法和用途 |
| CN120329440A (zh) * | 2024-01-18 | 2025-07-18 | 烁微生物医药(上海)有限公司 | 特异性结合hEGFR的单克隆抗体及双特异性抗体 |
| WO2025167743A1 (zh) * | 2024-02-06 | 2025-08-14 | 四川科伦博泰生物医药股份有限公司 | 抗体药物偶联物及其制备方法和用途 |
| WO2025180383A1 (en) * | 2024-02-26 | 2025-09-04 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Anti-tpbg/muc1 antibodies and uses thereof |
| WO2025180385A1 (en) * | 2024-02-27 | 2025-09-04 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Anti-egfr/cd70 antibodies and uses thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20250054125A (ko) * | 2012-11-21 | 2025-04-22 | 얀센 바이오테크 인코포레이티드 | 이중특이성 EGFR/c-Met 항체 |
| US9695228B2 (en) * | 2012-11-21 | 2017-07-04 | Janssen Biotech, Inc. | EGFR and c-Met fibronectin type III domain binding molecules |
| KR20150000795A (ko) * | 2013-06-25 | 2015-01-05 | 삼성전자주식회사 | 단백질 복합체, 이를 포함하는 c-Met과 EGFR에 대한 이중특이 항체, 및 그 제조 방법 |
| KR102089591B1 (ko) * | 2013-07-29 | 2020-03-18 | 삼성전자주식회사 | 항 EGFR scFv 단편 및 이를 포함하는 항 c-Met/항 EGFR 이중 특이 항체 |
| TW201609805A (zh) * | 2013-12-23 | 2016-03-16 | 美國禮來大藥廠 | 結合egfr及met之多功能抗體 |
| DK3665198T3 (da) * | 2017-08-09 | 2025-04-28 | Merus Nv | Antistoffer, der binder egfr og cmet |
| CN110028584B (zh) * | 2018-01-12 | 2021-04-06 | 北京科昕生物科技有限公司 | 针对egfr蛋白和met蛋白的双特异性抗体 |
| AU2020224136C1 (en) * | 2019-02-21 | 2025-09-25 | Regeneron Pharmaceuticals, Inc. | Methods of treating ocular cancer using anti-MET antibodies and bispecific antigen binding molecules that bind MET |
| US11879013B2 (en) * | 2019-05-14 | 2024-01-23 | Janssen Biotech, Inc. | Combination therapies with bispecific anti-EGFR/c-Met antibodies and third generation EGFR tyrosine kinase inhibitors |
| KR20230034957A (ko) * | 2020-06-19 | 2023-03-10 | 항저우 디에이씨 바이오테크 씨오, 엘티디 | 캄프토테신 유사체를 갖는 세포-결합 분자의 접합체 |
| WO2022104236A2 (en) * | 2020-11-16 | 2022-05-19 | Ab Therapeutics, Inc. | Multispecific antibodies and uses thereof |
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2023
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- 2023-06-29 CN CN202380050295.0A patent/CN119487075A/zh active Pending
- 2023-06-29 EP EP23830403.4A patent/EP4526354A1/en active Pending
- 2023-06-29 EP EP23830421.6A patent/EP4519321A4/en active Pending
- 2023-06-29 CA CA3260255A patent/CA3260255A1/en active Pending
- 2023-06-29 WO PCT/CN2023/103952 patent/WO2024002256A1/en not_active Ceased
- 2023-06-29 AU AU2023296688A patent/AU2023296688A1/en active Pending
- 2023-06-29 JP JP2024576707A patent/JP2025521703A/ja active Pending
- 2023-06-29 JP JP2024576364A patent/JP2025520772A/ja active Pending
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- 2023-06-29 KR KR1020247042802A patent/KR20250017243A/ko active Pending
- 2023-06-29 WO PCT/CN2023/103811 patent/WO2024002235A1/en not_active Ceased
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- 2024-12-09 MX MX2024015285A patent/MX2024015285A/es unknown
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Also Published As
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| AU2023296688A1 (en) | 2024-10-31 |
| KR20250028357A (ko) | 2025-02-28 |
| AU2023300794A1 (en) | 2024-12-19 |
| KR20250017243A (ko) | 2025-02-04 |
| WO2024002256A1 (en) | 2024-01-04 |
| CA3256857A1 (en) | 2024-01-04 |
| JP2025521703A (ja) | 2025-07-10 |
| EP4519321A4 (en) | 2026-01-14 |
| WO2024002235A1 (en) | 2024-01-04 |
| CA3260255A1 (en) | 2024-01-04 |
| MX2024015285A (es) | 2025-02-10 |
| US20250382373A1 (en) | 2025-12-18 |
| CN119487075A (zh) | 2025-02-18 |
| US20250122292A1 (en) | 2025-04-17 |
| CN119384433A (zh) | 2025-01-28 |
| EP4526354A1 (en) | 2025-03-26 |
| EP4519321A1 (en) | 2025-03-12 |
| JP2025520772A (ja) | 2025-07-03 |
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