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MX2024015072A - Anticuerpos anti-egfr/met y usos de los mismos - Google Patents

Anticuerpos anti-egfr/met y usos de los mismos

Info

Publication number
MX2024015072A
MX2024015072A MX2024015072A MX2024015072A MX2024015072A MX 2024015072 A MX2024015072 A MX 2024015072A MX 2024015072 A MX2024015072 A MX 2024015072A MX 2024015072 A MX2024015072 A MX 2024015072A MX 2024015072 A MX2024015072 A MX 2024015072A
Authority
MX
Mexico
Prior art keywords
egfr
antigen
met antibodies
binding protein
protein constructs
Prior art date
Application number
MX2024015072A
Other languages
English (en)
Inventor
Yanfei Han
Chengzhang Shang
Baihong Liu
Yi Yang
Yuelei Shen
Original Assignee
Biocytogen Pharmaceuticals Beijing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocytogen Pharmaceuticals Beijing Co Ltd filed Critical Biocytogen Pharmaceuticals Beijing Co Ltd
Publication of MX2024015072A publication Critical patent/MX2024015072A/es

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    • A61K38/07Tetrapeptides
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    • A61K38/08Peptides having 5 to 11 amino acids
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    • A61K47/6889Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se proporcionan construcciones de proteínas de unión a antígenos (por ejemplo, anticuerpos biespecíficos, fragmentos de unión a antígeno de los mismos o ADC), en donde las construcciones de proteína de unión a antígeno se unen específicamente a dos antígenos diferentes (por ejemplo, EGFR y MET).
MX2024015072A 2022-06-29 2024-12-05 Anticuerpos anti-egfr/met y usos de los mismos MX2024015072A (es)

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CN121194800A (zh) * 2023-05-12 2025-12-23 百奥赛图(北京)医药科技股份有限公司 接头化合物和配体-药物缀合物及其制备方法和用途
CN120329440A (zh) * 2024-01-18 2025-07-18 烁微生物医药(上海)有限公司 特异性结合hEGFR的单克隆抗体及双特异性抗体
WO2025167743A1 (zh) * 2024-02-06 2025-08-14 四川科伦博泰生物医药股份有限公司 抗体药物偶联物及其制备方法和用途
WO2025180383A1 (en) * 2024-02-26 2025-09-04 Biocytogen Pharmaceuticals (Beijing) Co., Ltd. Anti-tpbg/muc1 antibodies and uses thereof
WO2025180385A1 (en) * 2024-02-27 2025-09-04 Biocytogen Pharmaceuticals (Beijing) Co., Ltd. Anti-egfr/cd70 antibodies and uses thereof

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KR20250054125A (ko) * 2012-11-21 2025-04-22 얀센 바이오테크 인코포레이티드 이중특이성 EGFR/c-Met 항체
US9695228B2 (en) * 2012-11-21 2017-07-04 Janssen Biotech, Inc. EGFR and c-Met fibronectin type III domain binding molecules
KR20150000795A (ko) * 2013-06-25 2015-01-05 삼성전자주식회사 단백질 복합체, 이를 포함하는 c-Met과 EGFR에 대한 이중특이 항체, 및 그 제조 방법
KR102089591B1 (ko) * 2013-07-29 2020-03-18 삼성전자주식회사 항 EGFR scFv 단편 및 이를 포함하는 항 c-Met/항 EGFR 이중 특이 항체
TW201609805A (zh) * 2013-12-23 2016-03-16 美國禮來大藥廠 結合egfr及met之多功能抗體
DK3665198T3 (da) * 2017-08-09 2025-04-28 Merus Nv Antistoffer, der binder egfr og cmet
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