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MX2024008162A - Formulaciones parenterales estimulantes respiratorias. - Google Patents

Formulaciones parenterales estimulantes respiratorias.

Info

Publication number
MX2024008162A
MX2024008162A MX2024008162A MX2024008162A MX2024008162A MX 2024008162 A MX2024008162 A MX 2024008162A MX 2024008162 A MX2024008162 A MX 2024008162A MX 2024008162 A MX2024008162 A MX 2024008162A MX 2024008162 A MX2024008162 A MX 2024008162A
Authority
MX
Mexico
Prior art keywords
parenteral formulations
respiratory stimulant
compound
disclosed
stimulant
Prior art date
Application number
MX2024008162A
Other languages
English (en)
Inventor
Isaac Agyemang
Joseph V Pergolizzi
Frank Diana
Jiayi Chen
Devon E Dodd
Original Assignee
Enalare Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enalare Therapeutics Inc filed Critical Enalare Therapeutics Inc
Publication of MX2024008162A publication Critical patent/MX2024008162A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se divulga en ciertas modalidades una formulación parenteral que comprende un compuesto de Fórmula (I) como se divulga en la presente descripción y un excipiente farmacéuticamente aceptable, en donde la formulación mantiene al menos 90 % del compuesto después de condiciones de almacenamiento acelerado de 25 °C a 60 % de humedad relativa durante 2 semanas.
MX2024008162A 2021-12-27 2022-12-23 Formulaciones parenterales estimulantes respiratorias. MX2024008162A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163293985P 2021-12-27 2021-12-27
US202263313472P 2022-02-24 2022-02-24
PCT/US2022/053935 WO2023129502A1 (en) 2021-12-27 2022-12-23 Respiratory stimulant parenteral formulations

Publications (1)

Publication Number Publication Date
MX2024008162A true MX2024008162A (es) 2024-09-17

Family

ID=86992921

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2024008162A MX2024008162A (es) 2021-12-27 2022-12-23 Formulaciones parenterales estimulantes respiratorias.

Country Status (9)

Country Link
US (1) US20230210857A1 (es)
EP (1) EP4456900A4 (es)
JP (1) JP2025501169A (es)
KR (1) KR20240150426A (es)
AU (1) AU2022426492A1 (es)
CA (1) CA3242509A1 (es)
MX (1) MX2024008162A (es)
TW (1) TW202333732A (es)
WO (1) WO2023129502A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4543455A2 (en) * 2022-06-24 2025-04-30 Enalare Therapeutics Inc. Methods of treating neurological ventilatory insufficiency

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL130524A (en) * 1996-12-24 2005-08-31 Biogen Idec Inc Stable liquid interferon formulations, a kit containing the same and a process for stabilizing the same
BR112013013429A2 (pt) * 2010-11-29 2017-03-21 Galleon Pharmaceuticals Inc composição, método de prevenção ou tratamento de distúrbio ou doença de controle da respiração, e, método de prevenção de desestabilização ou estabilização do ritmo respiratório
US20120295911A1 (en) * 2010-11-29 2012-11-22 Galleon Pharmaceuticals, Inc. Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases
MX360638B (es) * 2011-04-28 2018-11-12 Univ Texas Formulaciones parenterales mejoradas de agentes farmacéuticos lipofílicos y métodos para prepararlos y usarlos.
BR112015011213A2 (pt) * 2012-11-15 2017-08-29 Galleon Pharmaceuticals Inc Composto, composição farmacêutica, método de prevenção ou tratamento de um distúrbio ou doença de controle respiratório em um indivíduo, método de prevenção de desestabilização ou de estabilização do ritmo respiratório em um indivíduo, método de preparação de o,n-dimetil-n-[4-(n-propilamina)-6-(prop-2-inilamina)-[1,3,5]triazin-2-il]-hidroxilamina, e composição.
GB201502412D0 (en) * 2015-02-13 2015-04-01 Canbex Therapeutics Ltd Therapeutic use

Also Published As

Publication number Publication date
JP2025501169A (ja) 2025-01-17
TW202333732A (zh) 2023-09-01
EP4456900A4 (en) 2025-12-24
AU2022426492A1 (en) 2024-07-18
US20230210857A1 (en) 2023-07-06
KR20240150426A (ko) 2024-10-15
CA3242509A1 (en) 2023-07-06
EP4456900A1 (en) 2024-11-06
WO2023129502A1 (en) 2023-07-06

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