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MX2024004355A - Tratamiento de la enfermedad renal. - Google Patents

Tratamiento de la enfermedad renal.

Info

Publication number
MX2024004355A
MX2024004355A MX2024004355A MX2024004355A MX2024004355A MX 2024004355 A MX2024004355 A MX 2024004355A MX 2024004355 A MX2024004355 A MX 2024004355A MX 2024004355 A MX2024004355 A MX 2024004355A MX 2024004355 A MX2024004355 A MX 2024004355A
Authority
MX
Mexico
Prior art keywords
kidney disease
treatment
therapeutic
kidney function
kidney
Prior art date
Application number
MX2024004355A
Other languages
English (en)
Inventor
Deepak Jain
Timothy A Bertram
Original Assignee
Timothy A Bertram
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Timothy A Bertram filed Critical Timothy A Bertram
Publication of MX2024004355A publication Critical patent/MX2024004355A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/22Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0684Cells of the urinary tract or kidneys
    • C12N5/0686Kidney cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Dermatology (AREA)

Abstract

En el presente documento se proporciona el uso de un agente terapéutico de células renales autólogas, por ejemplo, seleccionadas, para mejorar la función renal de un paciente humano que tiene enfermedad renal crónica diabética. El uso del terapéutico, administrado en la primera y segunda inyecciones, aumenta la función renal del paciente, por ejemplo, la tasa de filtración glomerular estimada, en el transcurso de al menos un año y estabiliza otros parámetros clínicos que disminuyen durante la enfermedad renal.
MX2024004355A 2021-10-14 2022-10-14 Tratamiento de la enfermedad renal. MX2024004355A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202163255885P 2021-10-14 2021-10-14
US202263307801P 2022-02-08 2022-02-08
US202263321204P 2022-03-18 2022-03-18
PCT/US2022/078153 WO2023064925A1 (en) 2021-10-14 2022-10-14 Treatment of kidney disease

Publications (1)

Publication Number Publication Date
MX2024004355A true MX2024004355A (es) 2024-06-21

Family

ID=85988933

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2024004355A MX2024004355A (es) 2021-10-14 2022-10-14 Tratamiento de la enfermedad renal.

Country Status (8)

Country Link
US (1) US20250009803A1 (es)
EP (1) EP4415729A4 (es)
JP (1) JP2024536479A (es)
KR (1) KR20240110801A (es)
AU (1) AU2022362077A1 (es)
CA (1) CA3233866A1 (es)
MX (1) MX2024004355A (es)
WO (1) WO2023064925A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025106530A1 (en) * 2023-11-13 2025-05-22 Butler Emily Characteristics of enriched heterogeneous renal cell populations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020223660A1 (en) * 2019-05-02 2020-11-05 Timothy Bertram Treatment of kidney disease in subjects with kidney and/or urinary tract anomalies

Also Published As

Publication number Publication date
WO2023064925A1 (en) 2023-04-20
CA3233866A1 (en) 2023-04-20
AU2022362077A1 (en) 2024-05-02
JP2024536479A (ja) 2024-10-04
WO2023064925A8 (en) 2024-04-11
EP4415729A1 (en) 2024-08-21
EP4415729A4 (en) 2025-08-27
US20250009803A1 (en) 2025-01-09
KR20240110801A (ko) 2024-07-16

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