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MX2024002281A - Anticuerpos anti-cd161 y usos de los mismos. - Google Patents

Anticuerpos anti-cd161 y usos de los mismos.

Info

Publication number
MX2024002281A
MX2024002281A MX2024002281A MX2024002281A MX2024002281A MX 2024002281 A MX2024002281 A MX 2024002281A MX 2024002281 A MX2024002281 A MX 2024002281A MX 2024002281 A MX2024002281 A MX 2024002281A MX 2024002281 A MX2024002281 A MX 2024002281A
Authority
MX
Mexico
Prior art keywords
antibodies
relates
mediated
making
pharmaceutical compositions
Prior art date
Application number
MX2024002281A
Other languages
English (en)
Inventor
Alison Tisdale
Uli Bialucha
George Punkosdy
Alexandria Fusco
Frano Irvine
Emily Rosentrater
Elizabeth Scanlon
Michael Battles
Original Assignee
Immunitas Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunitas Therapeutics Inc filed Critical Immunitas Therapeutics Inc
Publication of MX2024002281A publication Critical patent/MX2024002281A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La invención se refiere, en términos generales, a anticuerpos anti-CD161, a composiciones farmacéuticas que comprenden dichos anticuerpos y a métodos para usar dichos anticuerpos para el tratamiento contra trastornos asociados o mediados por CD161, por ejemplo, determinados tipos de cáncer. Además, la invención también se refiere a vectores de expresión y células hospederas para producir estos anticuerpos.
MX2024002281A 2021-08-23 2022-08-23 Anticuerpos anti-cd161 y usos de los mismos. MX2024002281A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163236122P 2021-08-23 2021-08-23
PCT/US2022/075370 WO2023028501A1 (en) 2021-08-23 2022-08-23 Anti-cd161 antibodies and uses thereof

Publications (1)

Publication Number Publication Date
MX2024002281A true MX2024002281A (es) 2024-05-20

Family

ID=83447883

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2024002281A MX2024002281A (es) 2021-08-23 2022-08-23 Anticuerpos anti-cd161 y usos de los mismos.

Country Status (11)

Country Link
US (3) US12215159B2 (es)
EP (1) EP4392451A1 (es)
JP (1) JP2024534265A (es)
KR (1) KR20240099138A (es)
CN (1) CN118284623A (es)
AU (1) AU2022332285A1 (es)
CA (1) CA3229448A1 (es)
IL (1) IL310662A (es)
MX (1) MX2024002281A (es)
WO (1) WO2023028501A1 (es)
ZA (1) ZA202401321B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3229448A1 (en) 2021-08-23 2023-03-02 Immunitas Therapeutics, Inc. Anti-cd161 antibodies and uses thereof
KR20260007566A (ko) * 2023-05-04 2026-01-14 노바센타, 인크. 항-cd161 항체 및 이의 사용 방법
WO2025111317A1 (en) * 2023-11-21 2025-05-30 The Brigham And Women's Hospital, Inc. Klrb1 binding agents and methods of use thereof
US20250197507A1 (en) * 2023-12-14 2025-06-19 Immunitas Therapeutics, Inc. Cd161 binding proteins and related methods
WO2025190375A1 (zh) * 2024-03-15 2025-09-18 深圳众格生物科技有限公司 抗cd161抗体及其用途
WO2025190376A1 (zh) * 2024-03-15 2025-09-18 深圳众格生物科技有限公司 抗cd161抗体及其用途

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Also Published As

Publication number Publication date
US20250122290A1 (en) 2025-04-17
US12304957B2 (en) 2025-05-20
EP4392451A1 (en) 2024-07-03
US20250243281A1 (en) 2025-07-31
CN118284623A (zh) 2024-07-02
AU2022332285A1 (en) 2024-02-15
IL310662A (en) 2024-04-01
JP2024534265A (ja) 2024-09-18
KR20240099138A (ko) 2024-06-28
ZA202401321B (en) 2025-05-28
US12215159B2 (en) 2025-02-04
WO2023028501A1 (en) 2023-03-02
CA3229448A1 (en) 2023-03-02
US20240279346A1 (en) 2024-08-22

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