MX2023014246A - Ensayos y reactivos de microchips de electroforesis capilar. - Google Patents
Ensayos y reactivos de microchips de electroforesis capilar.Info
- Publication number
- MX2023014246A MX2023014246A MX2023014246A MX2023014246A MX2023014246A MX 2023014246 A MX2023014246 A MX 2023014246A MX 2023014246 A MX2023014246 A MX 2023014246A MX 2023014246 A MX2023014246 A MX 2023014246A MX 2023014246 A MX2023014246 A MX 2023014246A
- Authority
- MX
- Mexico
- Prior art keywords
- reagents
- capillary electrophoresis
- tests
- electrophoresis microchip
- microchip
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44747—Composition of gel or of carrier mixture
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/24—Extraction; Separation; Purification by electrochemical means
- C07K1/26—Electrophoresis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44791—Microapparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Electrochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Se proporcionan ensayos y reactivos de microchips de electroforesis capilar (MCE) para evaluar la pureza y para identificar impurezas en las muestras de fármacos proteicos. Se proporcionan métodos para analizar los analitos en una muestra de fármaco proteico.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17/335,756 US12253490B2 (en) | 2018-03-19 | 2021-06-01 | Microchip capillary electrophoresis assays and reagents |
| US17/368,377 US12259355B2 (en) | 2018-03-19 | 2021-07-06 | Microchip capillary electrophoresis assays and reagents |
| PCT/US2022/031738 WO2022256383A1 (en) | 2021-06-01 | 2022-06-01 | Micropchip capillary electrophoresis assays and reagents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2023014246A true MX2023014246A (es) | 2024-01-17 |
Family
ID=82608737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023014246A MX2023014246A (es) | 2021-06-01 | 2022-06-01 | Ensayos y reactivos de microchips de electroforesis capilar. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP4348234A1 (es) |
| JP (1) | JP2024521871A (es) |
| KR (1) | KR20240015646A (es) |
| AU (1) | AU2022286340A1 (es) |
| BR (1) | BR112023024984A2 (es) |
| CA (1) | CA3220848A1 (es) |
| IL (1) | IL308864A (es) |
| MX (1) | MX2023014246A (es) |
| TW (1) | TW202314240A (es) |
| WO (1) | WO2022256383A1 (es) |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6927044B2 (en) | 1998-09-25 | 2005-08-09 | Regeneron Pharmaceuticals, Inc. | IL-1 receptor based cytokine traps |
| US7087411B2 (en) | 1999-06-08 | 2006-08-08 | Regeneron Pharmaceuticals, Inc. | Fusion protein capable of binding VEGF |
| DE10258150A1 (de) | 2002-12-10 | 2004-07-08 | Dyomics Gmbh | Hydrophile Marker auf der Basis von Benzopyrylo-Polymethinen |
| SI2041177T1 (sl) | 2006-06-02 | 2012-03-30 | Regeneron Pharma | Visoko afinitetna protitelesa za humani IL receptor |
| JP2009544974A (ja) * | 2006-07-21 | 2009-12-17 | ライフ テクノロジーズ コーポレーション | 鮮明に分解する標識タンパク質分子量標準 |
| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| ES2527297T3 (es) | 2007-07-31 | 2015-01-22 | Regeneron Pharmaceuticals, Inc. | Anticuerpos humanos para CD20 humano y método para utilizar los mismos |
| US8309088B2 (en) | 2007-08-10 | 2012-11-13 | Regeneron Pharmaceuticals, Inc. | Method of treating osteoarthritis with an antibody to NGF |
| JO3672B1 (ar) | 2008-12-15 | 2020-08-27 | Regeneron Pharma | أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9). |
| EP2975051B1 (en) | 2009-06-26 | 2021-04-14 | Regeneron Pharmaceuticals, Inc. | Readily isolated bispecific antibodies with native immunoglobulin format |
| JO3417B1 (ar) | 2010-01-08 | 2019-10-20 | Regeneron Pharma | الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r |
| JO3340B1 (ar) | 2010-05-26 | 2019-03-13 | Regeneron Pharma | مضادات حيوية لـعامل تمايز النمو 8 البشري |
| JOP20190250A1 (ar) | 2010-07-14 | 2017-06-16 | Regeneron Pharma | صيغ مستقرة تحتوي على الأجسام المضادة لمضاد عامل نمو الأعصاب |
| AR083044A1 (es) | 2010-09-27 | 2013-01-30 | Regeneron Pharma | Anticuerpos anti-cd48 y usos de los mismos |
| EP3354280B1 (en) | 2010-10-06 | 2020-07-29 | Regeneron Pharmaceuticals, Inc. | Stabilized formulations containing anti-interleukin-4 receptor (il-4r) antibodies |
| US8449880B2 (en) * | 2010-11-22 | 2013-05-28 | Vladislav Dolnik | Chemical modification of proteins for their more accurate molecular-weight determination by electrophoresis |
| JO3756B1 (ar) | 2010-11-23 | 2021-01-31 | Regeneron Pharma | اجسام مضادة بشرية لمستقبلات الجلوكاجون |
| AR087329A1 (es) | 2011-06-17 | 2014-03-19 | Regeneron Pharma | Anticuerpos humanos contra proteina 3 de tipo angiopoietina humana |
| PT2780368T (pt) | 2011-11-14 | 2018-03-22 | Regeneron Pharma | Composições e métodos para aumentar a massa muscular e a força muscular antagonizando especificamente gdf8 e/ou activina a |
| CN104169299B (zh) | 2012-01-23 | 2018-06-05 | 瑞泽恩制药公司 | 含抗Ang-2 抗体的稳定化制剂 |
| US9159537B2 (en) * | 2012-05-03 | 2015-10-13 | University Of Notre Dame Du Lac | Method for analyzing sample components |
| JO3820B1 (ar) | 2012-05-03 | 2021-01-31 | Regeneron Pharma | أجسام مضادة بشرية لـ fel d1وطرق لاستخدامها |
| TW201843172A (zh) | 2012-06-25 | 2018-12-16 | 美商再生元醫藥公司 | 抗-egfr抗體及其用途 |
| WO2014028354A1 (en) | 2012-08-13 | 2014-02-20 | Regeneron Pharmaceuticals, Inc. | Anti-pcsk9 antibodies with ph-dependent binding characteristics |
| JOP20200236A1 (ar) | 2012-09-21 | 2017-06-16 | Regeneron Pharma | الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها |
| JO3405B1 (ar) | 2013-01-09 | 2019-10-20 | Regeneron Pharma | الأجسام المضادة لمضاد مستقبل عامل النمو المشتق من الصفائح الدموية - بيتا واستخداماتها |
| JO3532B1 (ar) | 2013-03-13 | 2020-07-05 | Regeneron Pharma | الأجسام المضادة لمضاد انترلوكين-33 واستعمالاتها |
| TWI659968B (zh) | 2013-03-14 | 2019-05-21 | 再生元醫藥公司 | 針對呼吸道融合病毒f蛋白質的人類抗體及其使用方法 |
| CA2904377C (en) | 2013-03-15 | 2021-07-13 | Regeneron Pharmaceuticals, Inc. | Il-33 antagonists and uses thereof |
| TWI641620B (zh) | 2013-08-21 | 2018-11-21 | 再生元醫藥公司 | 抗-prlr抗體及其用途 |
| TWI681969B (zh) | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對pd-1的人類抗體 |
| TWI680138B (zh) | 2014-01-23 | 2019-12-21 | 美商再生元醫藥公司 | 抗pd-l1之人類抗體 |
| MY178160A (en) | 2014-03-11 | 2020-10-06 | Regeneron Pharma | Anti-egfrviii antibodies and uses thereof |
| TWI754319B (zh) | 2014-03-19 | 2022-02-01 | 美商再生元醫藥公司 | 用於腫瘤治療之方法及抗體組成物 |
| SG11201608696RA (en) | 2014-05-05 | 2016-11-29 | Regeneron Pharma | Humanized c5 and c3 animals |
| JO3701B1 (ar) | 2014-05-23 | 2021-01-31 | Regeneron Pharma | مضادات حيوية بشرية لمتلازمة الشرق الأوسط التنفسية - بروتين كورونا فيروس الشوكي |
| BR112017005110A2 (pt) | 2014-09-16 | 2018-01-23 | Regeneron Pharma | anticorpo monoclonal isolado ou fragmento de ligação ao antígeno do mesmo, molécula isolada de ácido nucleico, composição farmacêutica, e, método para diminuir níveis de glicose no sangue ou para tratar uma condição ou doença. |
| TWI710573B (zh) | 2015-01-26 | 2020-11-21 | 美商再生元醫藥公司 | 抗伊波拉病毒醣蛋白之人類抗體 |
| IL277264B2 (en) * | 2018-03-19 | 2024-03-01 | Regeneron Pharma | Microchip capillary electrophoresis assays and reagents |
-
2022
- 2022-06-01 KR KR1020237041580A patent/KR20240015646A/ko active Pending
- 2022-06-01 EP EP22743956.9A patent/EP4348234A1/en active Pending
- 2022-06-01 MX MX2023014246A patent/MX2023014246A/es unknown
- 2022-06-01 AU AU2022286340A patent/AU2022286340A1/en active Pending
- 2022-06-01 IL IL308864A patent/IL308864A/en unknown
- 2022-06-01 TW TW111120399A patent/TW202314240A/zh unknown
- 2022-06-01 CA CA3220848A patent/CA3220848A1/en active Pending
- 2022-06-01 JP JP2023573618A patent/JP2024521871A/ja active Pending
- 2022-06-01 BR BR112023024984A patent/BR112023024984A2/pt unknown
- 2022-06-01 WO PCT/US2022/031738 patent/WO2022256383A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| IL308864A (en) | 2024-01-01 |
| JP2024521871A (ja) | 2024-06-04 |
| WO2022256383A1 (en) | 2022-12-08 |
| AU2022286340A1 (en) | 2024-01-04 |
| BR112023024984A2 (pt) | 2024-02-20 |
| KR20240015646A (ko) | 2024-02-05 |
| EP4348234A1 (en) | 2024-04-10 |
| TW202314240A (zh) | 2023-04-01 |
| CA3220848A1 (en) | 2022-12-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR117402A1 (es) | Ensayos de electroforesis capilar de microchip y reactivos | |
| US9523684B2 (en) | Microfluidic devices and methods for separating and detecting constituents in a fluid sample | |
| US20110177618A1 (en) | Multi-Directional Microfluidic Devices and Methods | |
| ATE350666T1 (de) | Verfahren zur analyse von proteinproben | |
| ATE355126T1 (de) | Analytisches testelement und verfahren für blutuntersuchungen | |
| DE60330248D1 (de) | Teststreifen zum analytnachweis und verwendungsverfahren | |
| Niu et al. | Simultaneous pre-concentration and separation on simple paper-based analytical device for protein analysis | |
| DE60325847D1 (de) | Verbindungen und verfahren für die analyse des proteoms | |
| Ren et al. | Rapid enrichment and sensitive detection of extracellular vesicles through measuring the phospholipids and transmembrane protein in a microfluidic chip | |
| ATE433572T1 (de) | Methode, apparat, reagenzkit und reagenz zur unterscheidung von erythrozyten in biologischen proben | |
| Li et al. | Isoelectric focusing array with immobilized pH gradient and dynamic scanning imaging for diabetes diagnosis | |
| CN106940305A (zh) | 基于微流控芯片的抗生素检测装置和检测方法 | |
| EP3736571A4 (en) | METHOD, REAGENT AND CHIP FOR MEASURING THE ANALYTE CONCENTRATION IN A BIOLOGICAL SAMPLE | |
| Nielsen et al. | Microchip electrophoresis separation of a panel of preterm birth biomarkers | |
| AR126045A1 (es) | Ensayos y reactivos de microchips de electroforesis capilar | |
| MX2023014246A (es) | Ensayos y reactivos de microchips de electroforesis capilar. | |
| Zhao et al. | Microchip electrophoresis with chemiluminescence detection for assaying ascorbic acid and amino acids in single cells | |
| Zhao et al. | Quantification of carnosine-related peptides by microchip electrophoresis with chemiluminescence detection | |
| US9671368B2 (en) | Two-dimensional microfluidic devices and methods of using the same | |
| Zhao et al. | Determination of intracellular sulphydryl compounds by microchip electrophoresis with selective chemiluminescence detection | |
| EP4339604C0 (en) | SAMPLE ANALYSIS METHOD, CAPILLARY ELECTROPHORESIS SOLUTION AND SAMPLE ANALYSIS KIT | |
| JPWO2021070934A5 (es) | ||
| Damodara et al. | Single step separation and concentration of biomarker proteins using agarose based miniaturized isoelectric gates for point of care diagnostics | |
| EP4455666A4 (en) | Immunochromatography Diagnostic Stick and Immunochromatography Kit, Immunoassay Procedure Using It and Sample Filtration Procedure | |
| Huang et al. | Fast haptoglobin phenotyping based on microchip electrophoresis |