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MX2023002039A - Terapia metabolica del cancer. - Google Patents

Terapia metabolica del cancer.

Info

Publication number
MX2023002039A
MX2023002039A MX2023002039A MX2023002039A MX2023002039A MX 2023002039 A MX2023002039 A MX 2023002039A MX 2023002039 A MX2023002039 A MX 2023002039A MX 2023002039 A MX2023002039 A MX 2023002039A MX 2023002039 A MX2023002039 A MX 2023002039A
Authority
MX
Mexico
Prior art keywords
levels
diets
methionine
equal
activities
Prior art date
Application number
MX2023002039A
Other languages
English (en)
Inventor
Miguel López-Lázaro
José Manuel Calderón-Montaño
Julio José Jiménez-Alonso
Emilio Guillén-Mancina
Victor Jiménez-González
Alfonso Mate-Barrero
María Concepción Pérez-Guerrero
Estefanía Burgos-Morón
Original Assignee
Aminovita S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=73043291&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2023002039(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aminovita S L filed Critical Aminovita S L
Publication of MX2023002039A publication Critical patent/MX2023002039A/es

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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
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    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
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Abstract

El objetivo de la presente invención es cambiar el entorno metabólico normal de células cancerosas usando dietas artificiales en las que se manipulan los niveles y ratios de aminoácidos específicos y lípidos. Debido a sus alteraciones de ADN, las células cancerosas no serán capaces de adaptarse completamente al nuevo entorno metabólico, que reducirá su capacidad de supervivencia y su protección contra el sistema inmunitario. La presente invención proporciona composiciones de dieta artificial que inducen sorprendentes actividades antineoplásicas en modelos animales de cánceres metastásicos; estas actividades fueron superiores a las observadas en ratones que recibieron los tratamientos farmacológicos usados en pacientes con cáncer. La presente invención muestra que los niveles de metionina y leucina tienen un impacto importante sobre la actividad antineoplásica in vivo de las dietas. En todas las dietas activas, los niveles de metionina son inferiores o iguales a 0.6 % y los niveles de leucina son inferiores o iguales a 10 %, basado en el peso total de toda la composición seca.
MX2023002039A 2020-09-23 2020-09-23 Terapia metabolica del cancer. MX2023002039A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/ES2020/070571 WO2022064079A1 (es) 2020-09-23 2020-09-23 Terapia metabólica del cáncer

Publications (1)

Publication Number Publication Date
MX2023002039A true MX2023002039A (es) 2023-03-15

Family

ID=73043291

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023002039A MX2023002039A (es) 2020-09-23 2020-09-23 Terapia metabolica del cancer.

Country Status (11)

Country Link
US (1) US20230329304A1 (es)
EP (1) EP4190173B1 (es)
JP (1) JP7727286B2 (es)
KR (1) KR20230098562A (es)
CN (1) CN116096251A (es)
AU (1) AU2020468941A1 (es)
CA (1) CA3192176C (es)
ES (1) ES2989268T3 (es)
MX (1) MX2023002039A (es)
PL (1) PL4190173T3 (es)
WO (1) WO2022064079A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021283293B2 (en) 2020-06-03 2025-06-26 Faeth Therapeutics, Inc. Formulations for personalized methods of treatment
JP2023528930A (ja) 2020-06-04 2023-07-06 フェス・セラピューティクス，インコーポレーテッド がんを処置する個別化された方法
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