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MX2022013185A - Polipeptidos variantes proteoliticamente estables de u1-agatoxina-ta1b para el control de plagas. - Google Patents

Polipeptidos variantes proteoliticamente estables de u1-agatoxina-ta1b para el control de plagas.

Info

Publication number
MX2022013185A
MX2022013185A MX2022013185A MX2022013185A MX2022013185A MX 2022013185 A MX2022013185 A MX 2022013185A MX 2022013185 A MX2022013185 A MX 2022013185A MX 2022013185 A MX2022013185 A MX 2022013185A MX 2022013185 A MX2022013185 A MX 2022013185A
Authority
MX
Mexico
Prior art keywords
new
peptides
ta1b
agatoxin
pest control
Prior art date
Application number
MX2022013185A
Other languages
English (en)
Inventor
Ryan Garnett
Kyle Schneider
Alexandra Haase
Breck Davis
Original Assignee
Vestaron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vestaron Corp filed Critical Vestaron Corp
Publication of MX2022013185A publication Critical patent/MX2022013185A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50Isolated enzymes; Isolated proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/12Powders or granules
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01PBIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P7/00Arthropodicides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/55Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi
    • C12R2001/85Saccharomyces
    • C12R2001/87Saccharomyces lactis ; Kluyveromyces lactis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146Genetically Modified [GMO] plants, e.g. transgenic plants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Organic Chemistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Insects & Arthropods (AREA)
  • Biotechnology (AREA)
  • Dentistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Agronomy & Crop Science (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Nuevas proteínas insecticidas, nucleótidos, péptidos y su expresión en plantas. Métodos de producción de nuevos nucleótidos y nuevos péptidos, nuevos procesos, nuevas técnicas de producción, nuevas formulaciones y nuevos organismos. La presente descripción también está relacionada y describe nuevos péptidos denominados TVP, que son variaciones peptídicas no naturales basadas en la toxina U1-agatoxina-Ta1b derivada de la araña vagabunda. En la presente, se describen: genes que codifican TVP; formulaciones y combinaciones que comprenden genes y/o péptidos de TVP; y métodos que los usan que son útiles para el control de plagas.
MX2022013185A 2020-04-20 2021-04-20 Polipeptidos variantes proteoliticamente estables de u1-agatoxina-ta1b para el control de plagas. MX2022013185A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063012755P 2020-04-20 2020-04-20
PCT/US2021/028254 WO2021216621A2 (en) 2020-04-20 2021-04-20 Proteolytically stable u1-agatoxin-ta1b variant polypeptides for pest control

Publications (1)

Publication Number Publication Date
MX2022013185A true MX2022013185A (es) 2022-11-14

Family

ID=75787367

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022013185A MX2022013185A (es) 2020-04-20 2021-04-20 Polipeptidos variantes proteoliticamente estables de u1-agatoxina-ta1b para el control de plagas.

Country Status (19)

Country Link
US (1) US20230337684A1 (es)
EP (2) EP4139334B1 (es)
JP (1) JP2023522947A (es)
KR (1) KR20230013034A (es)
CN (1) CN116018350A (es)
AU (1) AU2021260878A1 (es)
BR (1) BR112022021268A2 (es)
CA (1) CA3180326A1 (es)
CL (2) CL2022002897A1 (es)
CO (1) CO2022014871A2 (es)
EC (1) ECSP22082339A (es)
ES (1) ES3005102T3 (es)
IL (1) IL297396A (es)
MX (1) MX2022013185A (es)
PE (1) PE20231212A1 (es)
PH (1) PH12022500014A1 (es)
PT (1) PT4139334T (es)
WO (1) WO2021216621A2 (es)
ZA (1) ZA202211136B (es)

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MX356526B (es) 2012-03-09 2018-06-01 Vestaron Corp Produccion de peptidos toxicos, expresion de peptido en plantas y combinaciones de peptidos ricos en cisteina.
IL297738A (en) * 2020-05-01 2022-12-01 Vestaron Corp Insecticidal combinations
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WO2024141641A2 (en) 2022-12-30 2024-07-04 Biotalys NV Secretion signals
WO2025133390A1 (en) 2023-12-22 2025-06-26 Biotalys NV Anti-fungal vhh antibodies
WO2025226701A1 (en) * 2024-04-23 2025-10-30 Vestaron Corporation Proteolytically stable u1-agatoxin-ta1b variant polypeptides for pest control
CN118325797B (zh) * 2024-06-14 2024-10-29 中国农业科学院北京畜牧兽医研究所 绿屈挠菌菌株lhy-1及其降解呕吐毒素的应用

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Also Published As

Publication number Publication date
ECSP22082339A (es) 2022-11-30
EP4139334A2 (en) 2023-03-01
BR112022021268A2 (pt) 2022-12-27
CL2022002897A1 (es) 2023-06-09
KR20230013034A (ko) 2023-01-26
JP2023522947A (ja) 2023-06-01
US20230337684A1 (en) 2023-10-26
CO2022014871A2 (es) 2023-02-16
PH12022500014A1 (en) 2023-06-14
ZA202211136B (en) 2023-06-28
CL2024000213A1 (es) 2024-07-12
WO2021216621A3 (en) 2021-12-16
EP4483718A2 (en) 2025-01-01
ES3005102T3 (en) 2025-03-13
EP4139334B1 (en) 2024-09-04
IL297396A (en) 2022-12-01
AU2021260878A1 (en) 2022-11-17
EP4483718A3 (en) 2025-03-26
CA3180326A1 (en) 2021-10-28
PT4139334T (pt) 2024-11-27
WO2021216621A2 (en) 2021-10-28
PE20231212A1 (es) 2023-08-17
CN116018350A (zh) 2023-04-25

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