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MX2022011077A - Variantes de transglutaminasa. - Google Patents

Variantes de transglutaminasa.

Info

Publication number
MX2022011077A
MX2022011077A MX2022011077A MX2022011077A MX2022011077A MX 2022011077 A MX2022011077 A MX 2022011077A MX 2022011077 A MX2022011077 A MX 2022011077A MX 2022011077 A MX2022011077 A MX 2022011077A MX 2022011077 A MX2022011077 A MX 2022011077A
Authority
MX
Mexico
Prior art keywords
variants
transglutaminase
transglutaminase variants
disclosed
preservatives
Prior art date
Application number
MX2022011077A
Other languages
English (en)
Inventor
Will Shindel
Erika Milczek
Original Assignee
Curie Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curie Co Inc filed Critical Curie Co Inc
Publication of MX2022011077A publication Critical patent/MX2022011077A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/02—Aminoacyltransferases (2.3.2)
    • C12Y203/02013—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/00041—Use of virus, viral particle or viral elements as a vector
    • C12N2795/00043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Birds (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se describen variantes de transglutaminasa. Se describen aplicaciones de uso para las variantes, incluyendo el uso como conservadores, agentes biocidas y para la modificación de proteínas.
MX2022011077A 2020-03-13 2021-03-10 Variantes de transglutaminasa. MX2022011077A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062988918P 2020-03-13 2020-03-13
PCT/US2021/021766 WO2021183680A1 (en) 2020-03-13 2021-03-10 Transglutaminase variants

Publications (1)

Publication Number Publication Date
MX2022011077A true MX2022011077A (es) 2022-09-23

Family

ID=77671938

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022011077A MX2022011077A (es) 2020-03-13 2021-03-10 Variantes de transglutaminasa.

Country Status (9)

Country Link
US (1) US20230167420A1 (es)
EP (1) EP4118194A4 (es)
JP (1) JP2023518714A (es)
KR (1) KR20220153047A (es)
CN (1) CN115298306A (es)
BR (1) BR112022017192A2 (es)
CA (1) CA3172844A1 (es)
MX (1) MX2022011077A (es)
WO (1) WO2021183680A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4526437A1 (en) 2022-05-20 2025-03-26 Curie Co. Inc. Pro-peptide variants for modulating activity of transglutaminases
CN115487345B (zh) * 2022-08-22 2024-03-12 天津大学 基于丝素蛋白的止血水凝胶和止血海绵及其制备方法和应用
CN121195062A (zh) 2023-05-19 2025-12-23 居里公司 转谷氨酰胺酶及其用途
CN117643311B (zh) * 2023-12-01 2024-09-27 北京舜雷科技有限公司 一种组合物、制备方法及应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE206765T1 (de) * 1994-02-14 2001-10-15 Univ Leiden Verfahren zum nachweis eines genetischen defektes,assoziert mit thrombose und/oder mangelhafter anticoagulanz-reaktion auf aktiviertes protein c
KR100565030B1 (ko) * 1999-09-30 2006-03-30 아지노모토 가부시키가이샤 트랜스글루타미나제의 제조방법
EP1310560A4 (en) * 2000-08-17 2005-07-13 Ajinomoto Kk METHOD FOR MODIFICATION OF TRANSGLUTAMINASE OF MICROORGANISMS (MTG)
EP1920050A1 (en) * 2005-08-18 2008-05-14 Novo Nordisk Health Care AG Improving transglutaminase substrate specificity
JP2008194004A (ja) * 2007-02-15 2008-08-28 Ajinomoto Co Inc 変異体トランスグルタミナーゼ
CN101631860B (zh) * 2007-02-15 2012-07-18 味之素株式会社 引入二硫键的转谷氨酰胺酶
EP2251421B1 (en) * 2008-02-13 2016-11-16 Amano Enzyme Inc. Stabilized transglutaminase and process for production thereof
WO2010101256A1 (ja) * 2009-03-06 2010-09-10 味の素株式会社 放線菌由来の耐熱性トランスグルタミナーゼ
WO2019014118A1 (en) * 2017-07-09 2019-01-17 Igc Bio, Inc. PROSS OPTIMIZED ENZYMES
CN107739734B (zh) * 2017-10-26 2020-07-07 江南大学 一种酶活提高的谷氨酰胺转氨酶突变体
CA3080512A1 (en) * 2017-11-07 2019-05-16 Codexis, Inc. Transglutaminase variants
US20200370026A1 (en) * 2017-11-30 2020-11-26 Amano Enzyme Inc. Modified transglutaminase
EP3934426A4 (en) * 2019-03-06 2022-12-14 Curie Co., Inc. Preservative compositions and methods of use thereof
EP4211233A4 (en) * 2020-09-08 2024-12-25 Curie Co. Inc. COMPOSITIONS AND METHODS OF USE THEREOF

Also Published As

Publication number Publication date
CA3172844A1 (en) 2021-09-16
WO2021183680A1 (en) 2021-09-16
BR112022017192A2 (pt) 2022-10-18
KR20220153047A (ko) 2022-11-17
CN115298306A (zh) 2022-11-04
EP4118194A4 (en) 2024-08-21
JP2023518714A (ja) 2023-05-08
US20230167420A1 (en) 2023-06-01
EP4118194A1 (en) 2023-01-18

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