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MX2022009447A - Uso de inhibidores de micro ácido ribonucleico 485 (miarn 485) para tratamiento de tauopatía. - Google Patents

Uso de inhibidores de micro ácido ribonucleico 485 (miarn 485) para tratamiento de tauopatía.

Info

Publication number
MX2022009447A
MX2022009447A MX2022009447A MX2022009447A MX2022009447A MX 2022009447 A MX2022009447 A MX 2022009447A MX 2022009447 A MX2022009447 A MX 2022009447A MX 2022009447 A MX2022009447 A MX 2022009447A MX 2022009447 A MX2022009447 A MX 2022009447A
Authority
MX
Mexico
Prior art keywords
mirna
inhibitors
gene expression
treating tauopathy
treating
Prior art date
Application number
MX2022009447A
Other languages
English (en)
Inventor
Jin-Hyeob Ryu
Hyun Su Min
Han Seok Koh
Dae Hoon Kim
Original Assignee
Biorchestra Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biorchestra Co Ltd filed Critical Biorchestra Co Ltd
Publication of MX2022009447A publication Critical patent/MX2022009447A/es

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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Abstract

La presente descripción incluye el uso de un inhibidor de miARN para el tratamiento de una tauopatía asociada con un nivel disminuido de expresión de proteína SIRT1 o del gen SIRT1, expresión de proteína PGC-1a y/o del gen PGC-1a, y/o expresión de proteína CD36 y/o del gen CD36.
MX2022009447A 2020-02-07 2021-02-06 Uso de inhibidores de micro ácido ribonucleico 485 (miarn 485) para tratamiento de tauopatía. MX2022009447A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202062971775P 2020-02-07 2020-02-07
US202062989489P 2020-03-13 2020-03-13
US202063047151P 2020-07-01 2020-07-01
PCT/IB2021/050976 WO2021156833A1 (en) 2020-02-07 2021-02-06 Use of mirna-485 inhibitors for treating tauopathy

Publications (1)

Publication Number Publication Date
MX2022009447A true MX2022009447A (es) 2022-11-09

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MX2022009447A MX2022009447A (es) 2020-02-07 2021-02-06 Uso de inhibidores de micro ácido ribonucleico 485 (miarn 485) para tratamiento de tauopatía.

Country Status (9)

Country Link
US (1) US20230099372A1 (es)
EP (1) EP4100065A4 (es)
JP (1) JP2023513190A (es)
KR (1) KR20220154106A (es)
CN (1) CN115461085A (es)
AU (1) AU2021215408A1 (es)
CA (1) CA3166604A1 (es)
MX (1) MX2022009447A (es)
WO (1) WO2021156833A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
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WO2021202511A2 (en) * 2020-03-30 2021-10-07 Alnylam Pharmaceuticals, Inc. MICROTUBULE ASSOCIATED PROTEIN TAU (MAPT) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF
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