[go: up one dir, main page]

MX2022007670A - Compuestos antihelminticos que comprenden una estructura de quinolina. - Google Patents

Compuestos antihelminticos que comprenden una estructura de quinolina.

Info

Publication number
MX2022007670A
MX2022007670A MX2022007670A MX2022007670A MX2022007670A MX 2022007670 A MX2022007670 A MX 2022007670A MX 2022007670 A MX2022007670 A MX 2022007670A MX 2022007670 A MX2022007670 A MX 2022007670A MX 2022007670 A MX2022007670 A MX 2022007670A
Authority
MX
Mexico
Prior art keywords
compounds
antihelmintic
quinoline structure
dirofilaria
quinoline
Prior art date
Application number
MX2022007670A
Other languages
English (en)
Inventor
Michael Berger
Michael Linder
Carolin Schneider
Janina Tänzler
Ulrich Sondern
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Publication of MX2022007670A publication Critical patent/MX2022007670A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a nuevos compuestos antihelmínticos. Estos compuestos se pueden usar por ejemplo en el tratamiento del tipo de helmintiasis causados por helmintos tal como Dirofilaria, en particular Dirofilaria immitis.
MX2022007670A 2019-12-18 2020-12-17 Compuestos antihelminticos que comprenden una estructura de quinolina. MX2022007670A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19217685 2019-12-18
EP20213298 2020-12-11
PCT/EP2020/086666 WO2021122911A1 (en) 2019-12-18 2020-12-17 Anthelmintic compounds comprising a quinoline structure

Publications (1)

Publication Number Publication Date
MX2022007670A true MX2022007670A (es) 2022-07-19

Family

ID=74130185

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022007670A MX2022007670A (es) 2019-12-18 2020-12-17 Compuestos antihelminticos que comprenden una estructura de quinolina.

Country Status (9)

Country Link
US (1) US12509449B2 (es)
EP (1) EP4077281A1 (es)
JP (2) JP2023507173A (es)
CN (1) CN114845994B (es)
AU (1) AU2020406093A1 (es)
BR (1) BR112022012126A2 (es)
CA (1) CA3164098A1 (es)
MX (1) MX2022007670A (es)
WO (1) WO2021122911A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL279977B2 (en) 2018-07-09 2024-06-01 Boehringer Ingelheim Animal Health Usa Inc Heterocyclic anthelmintic compounds
US11560388B2 (en) 2019-03-19 2023-01-24 Boehringer Ingelheim Vetmedica Gmbh Anthelmintic aza-benzothiophene and aza-benzofuran compounds
AU2021253168A1 (en) * 2020-04-09 2022-11-03 Elanco Animal Health Gmbh Substituted condensed azines as anthelmintic compounds
CA3183100A1 (en) 2020-05-29 2021-12-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anthelmintic heterocyclic compounds
AR127495A1 (es) 2021-11-01 2024-01-31 Boehringer Ingelheim Vetmedica Gmbh Compuestos de pirrolopiridazina como antihelmínticos
WO2024213752A1 (en) 2023-04-14 2024-10-17 Elanco Animal Health Gmbh Long-term prevention and/or treatment of a disease by slo-1 inhibitors
WO2025027117A1 (en) 2023-08-02 2025-02-06 Intervet International B.V. Carboxamide-4-quinoline compounds with anthelmintic activity

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0539588A1 (en) 1990-07-05 1993-05-05 Nippon Soda Co., Ltd. Amine derivative
US5399582A (en) 1993-11-01 1995-03-21 Merck & Co., Inc. Antiparasitic agents
US5595991A (en) 1995-03-20 1997-01-21 Merck & Co., Inc. Anthelmintic use of nodulisporic acid and analogs thereof
ATE435648T1 (de) 1995-03-20 2009-07-15 Merck & Co Inc Derivaten von nodulisporen säure
US6221894B1 (en) 1995-03-20 2001-04-24 Merck & Co., Inc. Nodulisporic acid derivatives
US5962499A (en) 1995-03-20 1999-10-05 Merck & Co., Inc. Nodulisporic acid derivatives
US5834260A (en) 1996-08-30 1998-11-10 Merck & Co., Inc. Antiparasitic agents
JP4758909B2 (ja) 2003-12-31 2011-08-31 シェーリング−プラウ・リミテッド イミダゾ［１，２−ｂ］ピリダジン誘導体を使用することによる動物における寄生生物の制御
US7361689B2 (en) 2003-12-31 2008-04-22 Schering-Plough Animal Health Corporation Antibacterial 1-(4-mono- and di-halomethylsulphonylphenyl)-2-acylamino-3-fluoroproponals and preparation thereof
CA2580843C (en) 2004-09-23 2011-03-29 Schering-Plough Ltd. Control of parasites in animals by the use of trifluoromethanesulfonanilide oxime ether derivatives
US7705038B2 (en) 2004-11-19 2010-04-27 Intervet, Inc. Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives
AR054380A1 (es) 2005-06-09 2007-06-20 Schering Plough Ltd Control de parasitos en animales con derivados de n- ((feniloxi) fenil) -1,1,1-trifluorometansulfonamida y de n-(fenilsulfanil) fenil) -1,1,1-trifluorometansulfonamida
DE102006015470A1 (de) 2006-03-31 2007-10-04 Bayer Cropscience Ag Substituierte Enaminocarbonylverbindungen
WO2010053517A2 (en) 2008-10-29 2010-05-14 Aroian Raffi V Combination therapy to combat helminth resistance
US8007761B2 (en) 2008-12-24 2011-08-30 Praxair Technology, Inc. Carbon dioxide emission reduction method
EP2990403A1 (en) 2014-08-29 2016-03-02 Novartis Tiergesundheit AG Anthranilamides, sulfonamides and nitro analogues derived therefrom as anthelmintics
WO2017178416A1 (en) 2016-04-15 2017-10-19 Bayer Animal Health Gmbh Pyrazolopyrimidine derivatives
AR108222A1 (es) 2016-05-05 2018-08-01 Elanco Tiergesundheit Ag Compuestos heteroaril-1,2,4-triazol y heteroaril-tetrazol
ES2884073T3 (es) 2016-11-11 2021-12-10 Bayer Animal Health Gmbh Nuevos derivados antihelmínticos de quinolina-3-carboxamida
AU2018311019B2 (en) 2017-08-04 2022-05-26 Elanco Animal Health Gmbh Quinoline derivatives for treating infections with helminths
BR112020016946A2 (pt) 2018-03-08 2020-12-15 Bayer Aktiengesellschaft Uso de compostos de heteroaril-triazol e heteroaril-tetrazol como pesticidas na proteção de plantas
BR112020018006A2 (pt) 2018-04-12 2021-01-12 Bayer Aktiengesellschaft Derivados de n-(ciclopropilmetil)-5-(metilsulfonil)-n-{1-[1-(pirimidin-2-il)-1h-1,2,4-triazol-5-il]etil}benzamida e os derivados correspondentes de piridina-carboxamida como pesticidas
UY38184A (es) 2018-04-17 2019-10-31 Bayer Ag Compuestos heteroarilo-triazol y heteroarilo-tetrazol novedosos como plaguicidas
AU2019260016B2 (en) 2018-04-25 2022-11-17 Bayer Aktiengesellschaft Novel heteroaryl-triazole and heteroaryl-tetrazole compounds as pesticides
CN112087951A (zh) 2018-05-08 2020-12-15 先正达农作物保护股份公司 施用某一种或多种杂芳基-1,2,4-三唑和杂芳基-四唑化合物来控制对植物、其繁殖材料和植物衍生产品的损害的方法
EP3790874B1 (en) 2018-05-09 2023-03-15 Bayer Animal Health GmbH Anthelmintic quinoline derivatives
UY38366A (es) 2018-09-13 2020-04-30 Syngenta Participations Ag Compuestos de azol-amida pesticidamente activos
TW202023386A (zh) 2018-09-13 2020-07-01 瑞士商先正達合夥公司 殺有害生物活性唑-醯胺化合物
CN112839933B (zh) 2018-10-02 2024-12-13 先正达参股股份有限公司 杀有害生物活性苯-酰胺和吖嗪-酰胺化合物
CN112888680A (zh) 2018-10-19 2021-06-01 先正达参股股份有限公司 杀有害生物活性的唑-酰胺化合物
US12152020B2 (en) 2018-11-05 2024-11-26 Syngenta Crop Protection Ag Pesticidally active azole-amide compounds
CN113490527B (zh) * 2018-12-18 2024-10-25 瑞士伊兰科动物保健有限公司 双环衍生物
EP3696175A1 (en) 2019-02-18 2020-08-19 Syngenta Crop Protection AG Pesticidally active azole-amide compounds
EP3941914A1 (en) 2019-03-22 2022-01-26 Syngenta Crop Protection AG N-[1-(5-bromo-2-pyrimidin-2-yl-1,2,4-triazol-3-yl)ethyl]-2-cyclopropyl-6-(trifluoromethyl)pyridine-4-carboxamide derivatives and related compounds as insecticides
UY38623A (es) 2019-03-29 2020-10-30 Syngenta Crop Protection Ag Compuestos de diazina-amida activos como pesticidas
MX2021012162A (es) 2019-04-05 2021-11-03 Syngenta Crop Protection Ag Compuestos de diazina-amida activos como pesticidas.
PE20220172A1 (es) 2019-04-11 2022-01-28 Syngenta Crop Protection Ag Compuestos de diazina-amida activos como pesticidas
EP3725788A1 (en) 2019-04-15 2020-10-21 Bayer AG Novel heteroaryl-substituted aminoalkyl azole compounds as pesticides
CN114072395A (zh) 2019-04-26 2022-02-18 新基公司 杂环化合物及其治疗蠕虫感染和疾病的用途

Also Published As

Publication number Publication date
JP2025134777A (ja) 2025-09-17
BR112022012126A2 (pt) 2022-08-30
US20230148316A1 (en) 2023-05-11
US12509449B2 (en) 2025-12-30
WO2021122911A1 (en) 2021-06-24
EP4077281A1 (en) 2022-10-26
CA3164098A1 (en) 2021-06-24
AU2020406093A1 (en) 2022-06-16
JP2023507173A (ja) 2023-02-21
CN114845994A (zh) 2022-08-02
CN114845994B (zh) 2025-07-18

Similar Documents

Publication Publication Date Title
MX2022007670A (es) Compuestos antihelminticos que comprenden una estructura de quinolina.
CO2019011543A2 (es) Inhibidores de pd-1/pd-l1
CO2018011105A2 (es) 6-hidroxi-4-oxo-1,4-dihidropirimidin-5-carboxamidas como agonistas del receptor de apelina (apj)
MX2018006503A (es) Compuesto novedoso de bifenilo o una sal del mismo.
CL2018001230A1 (es) Tratamiento de osteoartritis
BR112022012130A2 (pt) Compostos antelmínticos compreendendo uma estrutura azaindólica
UY37272A (es) Piridinas sustituidas con heteroarilo y métodos de uso
MX2017014956A (es) Agonistas de receptor de apelina (apj) de 4-hidroxi-3-(heteroaril) piridin-2-ona como para uso en el tratamiento de trastornos cardiovasculares.
SV2017005424A (es) Métodos para tratar infecciones por el virus filoviridae
CU24411B1 (es) Compuesto derivado de benzamida sustituida con 1,3-tiazol-2-ilo útil para el tratamiento de trastornos neurogénicos
UY35381A (es) Pirrolotriazinas como inhibidores del canal del ion potasio
CL2019000844A1 (es) Compuesto de piridina.
CO2018007221A2 (es) Heteroarilhidroxipirimidinonas como agonistas del receptor de apelina (apj)
CR20170285A (es) Compuestos de triazolopirimidina y usos de los mismos
CL2017001650A1 (es) Derivados de 5-[(piperazina-1-yl)-3-oxo-propilo]-imidazolidina-2,4-dionan como inhibidores adamts para el tratamiento oesteoartritis.
CU24408B1 (es) Compuestos de dihidroisoquinolinona sustituida
MX377384B (es) Derivados de bencimidazol como inhibidores de tirosina cinasa erbb para el tratamiento del cáncer.
CO2018000589A2 (es) Oxiesteroles y composiciones farmacéuticas que los contienen
UY36348A (es) Derivados de benzotiofenilo sustituidos como agonistas del gpr40 para el tratamiento de la diabetes tipo ii
UY36708A (es) MODULADORES DE ROR GAMMA (RORy)
MX2022000945A (es) Composicion para incrementar la expresion de pgc-1alfa.
MX2020006355A (es) Pirrolidinamidas ii sustituidas.
UY37774A (es) Compuestos 5-cianoindol sustituidos y usos de los mismos
CR20160459A (es) Nuevos derivados de piridina
MX375438B (es) Derivados de pirrolidinona como inhibidores de metionina aminopeptidasa 2 (metap-2).