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MX2022006078A - Terapias de combinacion para el tratamiento del cancer. - Google Patents

Terapias de combinacion para el tratamiento del cancer.

Info

Publication number
MX2022006078A
MX2022006078A MX2022006078A MX2022006078A MX2022006078A MX 2022006078 A MX2022006078 A MX 2022006078A MX 2022006078 A MX2022006078 A MX 2022006078A MX 2022006078 A MX2022006078 A MX 2022006078A MX 2022006078 A MX2022006078 A MX 2022006078A
Authority
MX
Mexico
Prior art keywords
treating cancer
combination therapies
variant
domain
combination
Prior art date
Application number
MX2022006078A
Other languages
English (en)
Inventor
Jaume Pons
Hong Wan
Sophia Randolph
Bang Janet Sim
Tracy Chia- Chien Kuo
Original Assignee
Alx Oncology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alx Oncology Inc filed Critical Alx Oncology Inc
Publication of MX2022006078A publication Critical patent/MX2022006078A/es

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    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Mycology (AREA)
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  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Se proporcionan métodos para el tratamiento del cáncer que comprenden administrar un polipéptido (p. ej., un polipéptido de fusión) que comprende una variante del dominio D1 de SIRPa y una variante del dominio Fc en combinación con al menos un agente quimioterapéutico y/o al menos un anticuerpo terapéutico. También se proporcionan kits relacionados.
MX2022006078A 2019-11-27 2020-11-25 Terapias de combinacion para el tratamiento del cancer. MX2022006078A (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201962941390P 2019-11-27 2019-11-27
US202063022998P 2020-05-11 2020-05-11
US202063030686P 2020-05-27 2020-05-27
US202063106225P 2020-10-27 2020-10-27
US202063109044P 2020-11-03 2020-11-03
PCT/US2020/062402 WO2021108693A1 (en) 2019-11-27 2020-11-25 Combination therapies for treating cancer

Publications (1)

Publication Number Publication Date
MX2022006078A true MX2022006078A (es) 2022-08-02

Family

ID=73854963

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022006078A MX2022006078A (es) 2019-11-27 2020-11-25 Terapias de combinacion para el tratamiento del cancer.

Country Status (11)

Country Link
US (3) US20210154269A1 (es)
EP (1) EP4065101A1 (es)
JP (2) JP7713447B2 (es)
KR (1) KR20220107223A (es)
CN (2) CN114845710A (es)
AU (1) AU2020394204A1 (es)
BR (1) BR112022008817A2 (es)
CA (1) CA3162633A1 (es)
IL (1) IL293199A (es)
MX (1) MX2022006078A (es)
WO (1) WO2021108693A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GEP20217326B (en) 2015-08-07 2021-11-25 Alx Oncology Inc Constructs having a sirp-alpha domain or variant thereof
AU2020282791A1 (en) 2019-05-31 2021-12-09 ALX Oncology Inc. Methods of treating cancer with SIRP alpha Fc fusion in combination with an immune checkpoint inhibitor
BR112022008817A2 (pt) 2019-11-27 2022-07-26 Alx Oncology Inc Terapias combinadas para tratamento de câncer
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