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MX2022005007A - Sólidos cristalinos de 3-palmitoil-amido-1, 2-propanodiol y 3-palmitoil-amido-2-hidroxi-1-dimetoxitrifenilmetileter-propano y métodos para elaborarlos y usarlos. - Google Patents

Sólidos cristalinos de 3-palmitoil-amido-1, 2-propanodiol y 3-palmitoil-amido-2-hidroxi-1-dimetoxitrifenilmetileter-propano y métodos para elaborarlos y usarlos.

Info

Publication number
MX2022005007A
MX2022005007A MX2022005007A MX2022005007A MX2022005007A MX 2022005007 A MX2022005007 A MX 2022005007A MX 2022005007 A MX2022005007 A MX 2022005007A MX 2022005007 A MX2022005007 A MX 2022005007A MX 2022005007 A MX2022005007 A MX 2022005007A
Authority
MX
Mexico
Prior art keywords
palmitoyl
amido
propanediol
hydroxy
dimethoxytriphenylmethylether
Prior art date
Application number
MX2022005007A
Other languages
English (en)
Inventor
Jennifer E Albaneze-Walker
Original Assignee
Geron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geron Corp filed Critical Geron Corp
Publication of MX2022005007A publication Critical patent/MX2022005007A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0004—Crystallisation cooling by heat exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0018—Evaporation of components of the mixture to be separated
    • B01D9/0031—Evaporation of components of the mixture to be separated by heating
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C07C231/24—Separation; Purification
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D2009/0086—Processes or apparatus therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Los aspectos de la descripción incluyen sólidos cristalinos de 3-palmitoil-amido-1,2-propanodiol y 3-palmitoil-amido-2-hidroxi-1- dimetoxitrifenilmetiléter-propano. También se proporcionan métodos para preparar los sólidos cristalinos de 3-palmitoil-amido-1,2-propanodiol y los monocristales 3-palmitoil-amido-2-hidroxi-1-dimetoxitrifenilmetiléter-propano. También se describen métodos para preparar un 3- palmitoil-amido-2-hidroxi-1-dimetoxitrifenilmetiléterpropano a partir de un sólido cristalino de 3-palmitoil-amido-1,2-propanodio l.
MX2022005007A 2019-10-28 2020-10-23 Sólidos cristalinos de 3-palmitoil-amido-1, 2-propanodiol y 3-palmitoil-amido-2-hidroxi-1-dimetoxitrifenilmetileter-propano y métodos para elaborarlos y usarlos. MX2022005007A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962926810P 2019-10-28 2019-10-28
PCT/US2020/057122 WO2021086754A1 (en) 2019-10-28 2020-10-23 Crystalline solids of 3-palmitoyl-amido-1,2-propanediol and 3-palmitoyl-amido-2-hydroxy-1-dimethoxytriphenylmethylether-propane and methods of making and using the same

Publications (1)

Publication Number Publication Date
MX2022005007A true MX2022005007A (es) 2022-08-08

Family

ID=75716187

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022005007A MX2022005007A (es) 2019-10-28 2020-10-23 Sólidos cristalinos de 3-palmitoil-amido-1, 2-propanodiol y 3-palmitoil-amido-2-hidroxi-1-dimetoxitrifenilmetileter-propano y métodos para elaborarlos y usarlos.

Country Status (11)

Country Link
US (2) US11987540B2 (es)
EP (1) EP4051252A4 (es)
JP (3) JP2022554244A (es)
KR (1) KR20220088444A (es)
CN (1) CN114901269A (es)
AU (1) AU2020375734A1 (es)
CA (1) CA3155391A1 (es)
IL (1) IL292327A (es)
MX (1) MX2022005007A (es)
TW (1) TW202132263A (es)
WO (1) WO2021086754A1 (es)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6448373B1 (en) * 1994-01-11 2002-09-10 Isis Pharmaceuticals, Inc. Phosphate linked oligomers formed of monomeric diols and processes for preparing same
US5801155A (en) 1995-04-03 1998-09-01 Epoch Pharmaceuticals, Inc. Covalently linked oligonucleotide minor grove binder conjugates
FR2850969B1 (fr) 2003-02-12 2005-03-25 Genfit S A Aminopropanediols acyles et analogues et leurs utilisations therapeutiques
FR2850870B1 (fr) 2003-02-12 2006-07-28 Genfit S A Utilisation therapeutique de glycerols acyles et de leurs analogues azotes et sulfures
FR2855823B1 (fr) * 2003-06-03 2007-09-21 Biochimie Appliquee Soc Nouveaux composes de type ceramide, leur procede de synthese, et compositions cosmetiques et/ou pharmaceutiques en contenant
SI3342425T1 (sl) 2003-09-09 2020-04-30 Geron Corporation Modificirani oligonukleotidi za inhibicijo telomeraze
US20120329858A1 (en) * 2010-08-04 2012-12-27 Geron Corporation Modified oligonucleotides for telomerase inhibition
EP2255787A4 (en) 2008-02-22 2014-08-27 Katayama Chemical Ind Co Ltd SYNTHETIC GLYCOLIPIDE-BASED LIPOSOMES
EP2646409A4 (en) 2010-11-25 2015-12-16 Shilpa Medicare Ltd FINGOLIMOD POLYMORPHES AND METHOD THEREFOR
JOP20200257A1 (ar) 2014-05-01 2017-06-16 Geron Corp تركيبات أوليجو نوكليوتيد وطرق لتحضيرها
HUE056722T2 (hu) 2017-07-10 2022-03-28 Geron Corp Javított eljárás imetelstat elõállítására
KR101809614B1 (ko) 2017-09-08 2017-12-15 (주)삼경코스텍 이소세리놀 아미드 유도체 및 이를 포함하는 조성물
KR101861785B1 (ko) 2017-09-08 2018-05-28 김명규 이소세리놀 아미드 유도체의 제조방법

Also Published As

Publication number Publication date
TW202132263A (zh) 2021-09-01
EP4051252A4 (en) 2023-12-06
WO2021086754A1 (en) 2021-05-06
IL292327A (en) 2022-06-01
US11987540B2 (en) 2024-05-21
EP4051252A1 (en) 2022-09-07
KR20220088444A (ko) 2022-06-27
AU2020375734A1 (en) 2022-05-26
JP2025107298A (ja) 2025-07-17
CA3155391A1 (en) 2021-05-06
JP2023174930A (ja) 2023-12-08
CN114901269A (zh) 2022-08-12
US20210147342A1 (en) 2021-05-20
US20240360074A1 (en) 2024-10-31
JP2022554244A (ja) 2022-12-28

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