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MX2022001731A - Tratamiento de cánceres con conjugados anticuerpo-farmaco (adc) que se unen a las proteínas 191p4d12. - Google Patents

Tratamiento de cánceres con conjugados anticuerpo-farmaco (adc) que se unen a las proteínas 191p4d12.

Info

Publication number
MX2022001731A
MX2022001731A MX2022001731A MX2022001731A MX2022001731A MX 2022001731 A MX2022001731 A MX 2022001731A MX 2022001731 A MX2022001731 A MX 2022001731A MX 2022001731 A MX2022001731 A MX 2022001731A MX 2022001731 A MX2022001731 A MX 2022001731A
Authority
MX
Mexico
Prior art keywords
adc
cancers
bind
proteins
treatment
Prior art date
Application number
MX2022001731A
Other languages
English (en)
Inventor
Oyewale O Abidoye
Original Assignee
Agensys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agensys Inc filed Critical Agensys Inc
Publication of MX2022001731A publication Critical patent/MX2022001731A/es

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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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  • Health & Medical Sciences (AREA)
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  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Biophysics (AREA)
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  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

En la presente se proporcionan métodos de tratamiento de cánceres con conjugados anticuerpo fármaco (ADC) que se unen a las proteínas 191P4D12.
MX2022001731A 2019-08-13 2020-08-10 Tratamiento de cánceres con conjugados anticuerpo-farmaco (adc) que se unen a las proteínas 191p4d12. MX2022001731A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962886270P 2019-08-13 2019-08-13
PCT/US2020/045567 WO2021030240A1 (en) 2019-08-13 2020-08-10 Treatment of cancers with antibody drug conjugates (adc) that bind to 191p4d12 proteins

Publications (1)

Publication Number Publication Date
MX2022001731A true MX2022001731A (es) 2022-07-13

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MX2022001731A MX2022001731A (es) 2019-08-13 2020-08-10 Tratamiento de cánceres con conjugados anticuerpo-farmaco (adc) que se unen a las proteínas 191p4d12.

Country Status (13)

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US (1) US20230001005A1 (es)
EP (1) EP4013795A4 (es)
JP (2) JP7657774B2 (es)
KR (1) KR20220054321A (es)
CN (1) CN114901690A (es)
AU (1) AU2020329761A1 (es)
BR (1) BR112022002391A2 (es)
CA (1) CA3150274A1 (es)
IL (1) IL290391A (es)
MX (1) MX2022001731A (es)
PH (1) PH12022550318A1 (es)
TW (2) TW202540197A (es)
WO (1) WO2021030240A1 (es)

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Publication number Priority date Publication date Assignee Title
JP7514834B2 (ja) 2018-12-03 2024-07-11 アジェンシス，インコーポレイテッド 抗１９１ｐ４ｄ１２抗体薬物コンジュゲートを含む薬学的組成物、およびその使用方法
WO2021221500A1 (en) * 2020-04-27 2021-11-04 Agendia N.V. Treatment of her2 negative, mammaprint high risk 2 breast cancer.
WO2022076767A1 (en) * 2020-10-11 2022-04-14 Agensys, Inc. Methods for treating cancers with antibody drug conjugates (adc) that bind to 191p4d12 proteins
US20260008848A1 (en) * 2022-07-14 2026-01-08 Bio-Thera Solutions, Ltd. Anti-nectin-4 antibody, and antibody-drug conjugate and use thereof
EP4671280A1 (en) 2023-02-22 2025-12-31 Nanjing Leads Biolabs Co., Ltd. ANTI-NECTIN-4 ANTIBODY AND MULTISPECIFIC ANTIBODY CONTAINER
KR20250057677A (ko) * 2023-10-19 2025-04-29 (주)셀트리온 캄프토테신 유도체를 포함하는 항-Nectin-4 항체-약물 접합체

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3903812A1 (en) * 2010-09-29 2021-11-03 Agensys, Inc. Antibody drug conjugates (adc) that bind to 191p4d12 proteins
AU2011328932B2 (en) * 2010-11-16 2016-06-02 InnerGeo LLC System and method for extracting energy
CA2985483A1 (en) * 2015-06-08 2016-12-15 Genentech, Inc. Methods of treating cancer using anti-ox40 antibodies
BR112019002405A2 (pt) * 2016-08-26 2019-06-04 Hydril Usa Distrib Llc conjunto de transdutor para riser de perfuração offshore
JP7514834B2 (ja) * 2018-12-03 2024-07-11 アジェンシス，インコーポレイテッド 抗１９１ｐ４ｄ１２抗体薬物コンジュゲートを含む薬学的組成物、およびその使用方法

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KR20220054321A (ko) 2022-05-02
CA3150274A1 (en) 2021-02-18
CN114901690A (zh) 2022-08-12
JP7657774B2 (ja) 2025-04-07
TWI873167B (zh) 2025-02-21
PH12022550318A1 (en) 2023-02-13
JP2022544227A (ja) 2022-10-17
EP4013795A1 (en) 2022-06-22
IL290391A (en) 2022-04-01
US20230001005A1 (en) 2023-01-05
JP2025106332A (ja) 2025-07-15
EP4013795A4 (en) 2023-11-15
WO2021030240A1 (en) 2021-02-18
TW202540197A (zh) 2025-10-16
TW202120557A (zh) 2021-06-01
AU2020329761A1 (en) 2022-03-03
BR112022002391A2 (pt) 2022-12-13

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