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MX2022000497A - Edicion de acido ribonucleico (arn) dirigido aprovechando la adenosina desaminasa que actua sobre acido ribonucleico endogeno (adar) utilizando acidos ribonucleicos (arn) modificados geneticamente. - Google Patents

Edicion de acido ribonucleico (arn) dirigido aprovechando la adenosina desaminasa que actua sobre acido ribonucleico endogeno (adar) utilizando acidos ribonucleicos (arn) modificados geneticamente.

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Publication number
MX2022000497A
MX2022000497A MX2022000497A MX2022000497A MX2022000497A MX 2022000497 A MX2022000497 A MX 2022000497A MX 2022000497 A MX2022000497 A MX 2022000497A MX 2022000497 A MX2022000497 A MX 2022000497A MX 2022000497 A MX2022000497 A MX 2022000497A
Authority
MX
Mexico
Prior art keywords
ribonucleic acid
rna
adar
endogenous
edition
Prior art date
Application number
MX2022000497A
Other languages
English (en)
Inventor
Feng Tian
Chunhui Wang
Wensheng Wei
Liang Qu
Zongyi Yi
Shiyou Zhu
Zhuo Zhou
Original Assignee
Univ Beijing
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Beijing filed Critical Univ Beijing
Publication of MX2022000497A publication Critical patent/MX2022000497A/es

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    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
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    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente solicitud proporciona métodos para editar ARN mediante la introducción de un ARN de reclutamiento de desaminasas en una célula hospedera para la desaminación de una adenosina en un ARN objetivo; la presente solicitud proporciona además ARN de reclutamiento de desaminasas usados en los métodos de edición de ARN y composiciones y kits que comprenden los mismos.
MX2022000497A 2019-07-12 2020-07-10 Edicion de acido ribonucleico (arn) dirigido aprovechando la adenosina desaminasa que actua sobre acido ribonucleico endogeno (adar) utilizando acidos ribonucleicos (arn) modificados geneticamente. MX2022000497A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2019095802 2019-07-12
PCT/CN2020/101246 WO2021008447A1 (en) 2019-07-12 2020-07-10 Targeted rna editing by leveraging endogenous adar using engineered rnas

Publications (1)

Publication Number Publication Date
MX2022000497A true MX2022000497A (es) 2022-02-03

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MX2022000497A MX2022000497A (es) 2019-07-12 2020-07-10 Edicion de acido ribonucleico (arn) dirigido aprovechando la adenosina desaminasa que actua sobre acido ribonucleico endogeno (adar) utilizando acidos ribonucleicos (arn) modificados geneticamente.

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Country Link
US (3) US20220243194A1 (es)
EP (1) EP3997229A4 (es)
JP (1) JP7651190B2 (es)
KR (1) KR102866423B1 (es)
CN (2) CN114269919B (es)
AU (1) AU2020313143B2 (es)
CA (1) CA3146771A1 (es)
CL (1) CL2022000080A1 (es)
CO (1) CO2022001359A2 (es)
CR (1) CR20220063A (es)
EC (1) ECSP22010372A (es)
IL (1) IL289700A (es)
MX (1) MX2022000497A (es)
PE (1) PE20220300A1 (es)
PH (1) PH12022550059A1 (es)
WO (1) WO2021008447A1 (es)

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