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MX2021014118A - Method for expanding adult stem cells from whole blood. - Google Patents

Method for expanding adult stem cells from whole blood.

Info

Publication number
MX2021014118A
MX2021014118A MX2021014118A MX2021014118A MX2021014118A MX 2021014118 A MX2021014118 A MX 2021014118A MX 2021014118 A MX2021014118 A MX 2021014118A MX 2021014118 A MX2021014118 A MX 2021014118A MX 2021014118 A MX2021014118 A MX 2021014118A
Authority
MX
Mexico
Prior art keywords
stem cells
blood
adult stem
whole blood
expanding adult
Prior art date
Application number
MX2021014118A
Other languages
Spanish (es)
Inventor
Marco Polettini
Original Assignee
Thankstem S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thankstem S R L filed Critical Thankstem S R L
Publication of MX2021014118A publication Critical patent/MX2021014118A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0644—Platelets; Megakaryocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/02—Atmosphere, e.g. low oxygen conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Method for expanding adult stem cells from blood comprising the growth and deprogramming of the adult blood stem cells of a blood sample, by means of in vitro treatment of the blood sample with a PRP-based blood derivative product which includes autologous MCSF obtained by platelet lysis in a portion of the same autologous blood sample.
MX2021014118A 2019-05-22 2020-05-19 Method for expanding adult stem cells from whole blood. MX2021014118A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT201900007076 2019-05-22
PCT/IT2020/050126 WO2020234910A1 (en) 2019-05-22 2020-05-19 Method for expanding adult stem cells from whole blood

Publications (1)

Publication Number Publication Date
MX2021014118A true MX2021014118A (en) 2021-12-10

Family

ID=67875993

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021014118A MX2021014118A (en) 2019-05-22 2020-05-19 Method for expanding adult stem cells from whole blood.

Country Status (6)

Country Link
EP (1) EP3973051A1 (en)
CN (1) CN113924361A (en)
AU (1) AU2020277774A1 (en)
BR (1) BR112021023101A2 (en)
MX (1) MX2021014118A (en)
WO (1) WO2020234910A1 (en)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070122906A1 (en) * 2003-12-29 2007-05-31 Allan Mishra Method of culturing cells
ITRM20060498A1 (en) * 2006-09-20 2008-03-21 Alessandra Gambacurta METHOD OF EXPANSION OF ADULT STEM CELLS FROM PERIPHERAL BLOOD AND RELATED USES IN MEDICAL FIELD
IT1392897B1 (en) * 2008-07-18 2012-04-02 Fond Ircss Ca' Granda - Ospedale Maggiore Policlinico PIASTRINIC FRACTION DERIVING FROM PLACENTED BLOOD
US9688959B2 (en) * 2011-06-27 2017-06-27 Emory University Compositions, uses, and preparation of platelet lysates
ITRM20110500A1 (en) * 2011-09-23 2013-03-24 Futura Stem Cells Sa LYSATE PIASTRINICO, USE OF IT AND METHOD FOR ITS PREPARATION
CN102367435B (en) * 2011-11-04 2013-01-16 四川新生命干细胞科技股份有限公司 Preparation of human platelet-rich plasma and application of same in isolation and culture of human mesenchymal stem cells
CN102533641B (en) * 2012-02-20 2016-08-17 光丽生医股份有限公司 In vitro serum-free adult stem cell scale-up culture method and its culture medium
US20140356893A1 (en) * 2013-06-04 2014-12-04 Allan Mishra Compositions and methods for using platelet-rich plasma for drug discovery, cell nuclear reprogramming, proliferation or differentiation
JP6664382B2 (en) * 2014-05-09 2020-03-13 サンクステム エス・アール・エル How to grow adult stem cells from whole blood
CA3033750A1 (en) * 2016-08-29 2018-03-08 Hackensack University Medical Center Compositions and methods for programming adult cells with platelet rich fraction of blood containing platelet-like cells

Also Published As

Publication number Publication date
WO2020234910A1 (en) 2020-11-26
AU2020277774A1 (en) 2021-12-09
EP3973051A1 (en) 2022-03-30
CN113924361A (en) 2022-01-11
BR112021023101A2 (en) 2022-01-04

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