MX2021011695A - Implantes alogenicos para el tratamiento de lesiones de cartilago. - Google Patents
Implantes alogenicos para el tratamiento de lesiones de cartilago.Info
- Publication number
- MX2021011695A MX2021011695A MX2021011695A MX2021011695A MX2021011695A MX 2021011695 A MX2021011695 A MX 2021011695A MX 2021011695 A MX2021011695 A MX 2021011695A MX 2021011695 A MX2021011695 A MX 2021011695A MX 2021011695 A MX2021011695 A MX 2021011695A
- Authority
- MX
- Mexico
- Prior art keywords
- cartilage
- injury
- relates
- cartilage injuries
- treating cartilage
- Prior art date
Links
- 206010007710 Cartilage injury Diseases 0.000 title abstract 3
- 239000007943 implant Substances 0.000 title 1
- 210000000845 cartilage Anatomy 0.000 abstract 2
- 210000001612 chondrocyte Anatomy 0.000 abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- 108010080379 Fibrin Tissue Adhesive Proteins 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 230000000735 allogeneic effect Effects 0.000 abstract 1
- 210000001188 articular cartilage Anatomy 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 230000035876 healing Effects 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Materials Engineering (AREA)
- Cardiology (AREA)
- Composite Materials (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Abstract
En la presente invención se provee un injerto o constructo conformado por condrocitos aislados de cartílago, proveniente de donadores jóvenes (<20 años), sembrados sobre una membrana tridimensional, compuesta por una de las principales sustancias promotoras de condrogénesis (ácido hialurónico), en altas densidades (1x106) con suero autólogo y sellados con una adhesivo de fibrina para el tratamiento de una lesión de cartílago, con formación de tejido que tenga una mayor durabilidad, a un menor costo y con menos riesgos que los tratamientos disponibles en la actualidad para el manejo de dichas lesiones. Así mismo se provee un procedimiento para el tratamiento de lesiones de cartílago articular, mediante la implantación de del injerto de condrocitos alogénicos que presentan la capacidad de generar o reparar de manera satisfactoria el cartílago de la lesión.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2021011695A MX2021011695A (es) | 2021-09-24 | 2021-09-24 | Implantes alogenicos para el tratamiento de lesiones de cartilago. |
| PCT/MX2022/050017 WO2023048552A1 (es) | 2021-09-24 | 2022-03-11 | Implantes alogénicos para el tratamiento de lesiones de cartilago |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2021011695A MX2021011695A (es) | 2021-09-24 | 2021-09-24 | Implantes alogenicos para el tratamiento de lesiones de cartilago. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021011695A true MX2021011695A (es) | 2022-03-03 |
Family
ID=85720971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021011695A MX2021011695A (es) | 2021-09-24 | 2021-09-24 | Implantes alogenicos para el tratamiento de lesiones de cartilago. |
Country Status (2)
| Country | Link |
|---|---|
| MX (1) | MX2021011695A (es) |
| WO (1) | WO2023048552A1 (es) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2367694T3 (es) * | 2003-12-11 | 2011-11-07 | Isto Technologies Inc. | Sistema de cartílago particulado. |
-
2021
- 2021-09-24 MX MX2021011695A patent/MX2021011695A/es unknown
-
2022
- 2022-03-11 WO PCT/MX2022/050017 patent/WO2023048552A1/es not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2023048552A1 (es) | 2023-03-30 |
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