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MX2021004464A - Compuestos de tiazolida para el tratamiento de infecciones virales. - Google Patents

Compuestos de tiazolida para el tratamiento de infecciones virales.

Info

Publication number
MX2021004464A
MX2021004464A MX2021004464A MX2021004464A MX2021004464A MX 2021004464 A MX2021004464 A MX 2021004464A MX 2021004464 A MX2021004464 A MX 2021004464A MX 2021004464 A MX2021004464 A MX 2021004464A MX 2021004464 A MX2021004464 A MX 2021004464A
Authority
MX
Mexico
Prior art keywords
viral infections
treating viral
thiazolide compounds
thiazolide
compounds
Prior art date
Application number
MX2021004464A
Other languages
English (en)
Inventor
Maria Gabriella Santoro
Jean - Francois ROSSIGNOL
Original Assignee
Romark Laboratories Lc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romark Laboratories Lc filed Critical Romark Laboratories Lc
Publication of MX2021004464A publication Critical patent/MX2021004464A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Los compuestos de tiazolida, tales como nitazoxanida y/o tizoxanida, pueden usarse contra los virus que pertenecen a la familia Picornaviridae o a la familia Paramyxoviridae.
MX2021004464A 2016-03-31 2018-09-28 Compuestos de tiazolida para el tratamiento de infecciones virales. MX2021004464A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662316463P 2016-03-31 2016-03-31

Publications (1)

Publication Number Publication Date
MX2021004464A true MX2021004464A (es) 2021-06-04

Family

ID=58530692

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2018011938A MX381896B (es) 2016-03-31 2017-03-30 Compuestos de tiazolida para el tratamiento de infecciones virales.
MX2021004464A MX2021004464A (es) 2016-03-31 2018-09-28 Compuestos de tiazolida para el tratamiento de infecciones virales.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2018011938A MX381896B (es) 2016-03-31 2017-03-30 Compuestos de tiazolida para el tratamiento de infecciones virales.

Country Status (26)

Country Link
US (2) US11135202B2 (es)
EP (2) EP3677282A1 (es)
JP (2) JP6567781B2 (es)
KR (3) KR102136803B1 (es)
CN (1) CN108289961A (es)
AU (2) AU2017244145B2 (es)
BR (1) BR112018069974A2 (es)
CA (2) CA3113354A1 (es)
CY (1) CY1123221T1 (es)
DK (1) DK3436074T3 (es)
EA (2) EA036505B1 (es)
ES (1) ES2810303T3 (es)
HK (1) HK1250945A1 (es)
HR (1) HRP20201261T1 (es)
HU (1) HUE050601T2 (es)
IL (2) IL262018A (es)
LT (1) LT3436074T (es)
MX (2) MX381896B (es)
PH (1) PH12018502058A1 (es)
PL (1) PL3436074T3 (es)
PT (1) PT3436074T (es)
SG (1) SG11201808453UA (es)
SI (1) SI3436074T1 (es)
UA (1) UA126114C2 (es)
WO (1) WO2017173056A1 (es)
ZA (1) ZA201806644B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111012778B (zh) * 2018-10-10 2022-06-24 北京市农林科学院 Nitazoxanide在抑制犬细小病毒中的应用
CN109536460A (zh) * 2018-12-07 2019-03-29 中国医学科学院医学生物学研究所 一种cv-a10病毒毒种及其人用灭活疫苗
CN110787161B (zh) * 2019-09-19 2022-09-27 中山大学 噻唑类化合物用于抗鱼类病毒的新用途
CN111012788B (zh) * 2019-12-12 2021-01-15 武汉职业技术学院 硝唑尼特和替唑尼特在制备抗猪繁殖与呼吸综合征病毒药物中的应用
US20230303504A1 (en) * 2020-07-20 2023-09-28 Romark Laboratories, L.C. Crystalline salts of tizoxanide and 2-hydroxy-n-(5-chloro-1,3-thiazol-2-yl)benzamide (rm-4848) with ethanolamine, morpholine, propanolamine, piperazine and n-methylpiperazine
JP2023538136A (ja) 2020-08-24 2023-09-06 ロマーク ラボラトリーズ，リミティド カンパニー コロナウイルスに対するチアゾリドの利用
EP4337200A4 (en) * 2021-05-28 2025-01-22 Henderson, Theodore TREATMENT WITH AN ANTIVIRAL COMPOUND AND NITAZOXANIDE
CN118317775A (zh) 2021-09-15 2024-07-09 南京强新生物医药有限公司 治疗冠状病毒感染的新联用药物、药物组合物及其用途
CN114404439B (zh) * 2022-02-11 2023-07-11 山东农业大学 抑制不同类型猪繁殖与呼吸综合症病毒感染的阻断剂
CN116966178B (zh) * 2022-04-29 2025-10-03 成都贝诺科成生物科技有限公司 一种氨基硝基噻唑衍生物在制备预防和治疗病毒感染及其引起的相关疾病的药物中的用途
CN118161479B (zh) * 2024-03-12 2025-01-28 中国动物卫生与流行病学中心 银杏双黄酮在制备抗猪塞内卡病毒的制剂中的应用

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GB1437800A (en) 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
US5387598A (en) 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen
MX9604483A (es) 1994-09-08 1998-02-28 Jean-Francois Rossignol Derivados de benzamida, composiciones que contienen dicho derivado y uso de las mismas.
US5968961A (en) 1997-05-07 1999-10-19 Romark Laboratories, L.C. Pharmaceutical compositions of tizoxanide and nitazoxanide
US5856348A (en) 1994-09-08 1999-01-05 Romark Laboratories, L.C. Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
US5965590A (en) 1994-09-08 1999-10-12 Romark Lab Lc Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
US5859038A (en) 1994-09-08 1999-01-12 Romark Laboratories, L.C. Method for treatment of helicobacter pylori infections
US5935591A (en) 1998-01-15 1999-08-10 Romark Laboratories, L.C. Method for treatment of equine protozoal myeloencephalitis with thiazolides
CA2522007A1 (en) 2003-04-11 2004-10-28 Medimmune, Inc. Methods of preventing or treating respiratory conditions
UA90864C2 (en) 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives
US20060194853A1 (en) 2004-10-08 2006-08-31 Rossignol Jean F Alkyl benzamides
CA2604640A1 (en) * 2005-04-12 2006-10-19 Romark Laboratories L.C. Methods for treating diseases through interruption of protein maturation, compounds that inhibit the function of molecular chaperones such as protein disulfide isomerases or interfere with glycosylation, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents
AU2007204963B2 (en) 2006-01-09 2012-09-27 Romark Laboratories, L.C. Viral hepatitis treatment
CN101835765B (zh) 2007-08-03 2013-05-29 罗马克实验室有限公司 烷基磺酰基取代的噻唑化物类化合物
GB0716292D0 (en) * 2007-08-21 2007-09-26 Biofocus Dpi Ltd Imidazopyrazine compounds
LT2395840T (lt) 2009-02-13 2020-07-10 Romark Laboratories, L.C. Nitazoksanido kontroliuojamo atpalaidavimo farmacinės kompozicijos
AP3074A (en) 2009-05-12 2014-12-31 Romark Lab Lc Haloalkyl heteroaryl benzamide compounds
PT2445349T (pt) * 2009-06-26 2022-05-16 Romark Laboratories Lc Compostos e métodos para tratamento da gripe
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JP6138764B2 (ja) 2011-05-16 2017-05-31 ロマーク ラボラトリーズ エル．シー． ウイルス性疾患、ガンおよび細胞内感染により引き起こされる疾患の予防および処置のためのチアゾリド化合物の使用
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CN113712989A (zh) * 2013-10-11 2021-11-30 艾丽奥斯生物制药有限公司 取代的核苷、核苷酸及其类似物
US10328128B2 (en) * 2014-09-17 2019-06-25 Ansun Biopharma, Inc. Treatment of infection by human enterovirus D68
US10100023B2 (en) 2014-11-11 2018-10-16 Romark Laboratories, L.C. Compositions and methods of treatment with prodrugs of tizoxanide, an analogue or salt thereof

Also Published As

Publication number Publication date
HK1250945A1 (zh) 2019-01-18
WO2017173056A1 (en) 2017-10-05
SI3436074T1 (sl) 2020-09-30
IL280327A (en) 2021-03-01
HRP20201261T1 (hr) 2021-02-05
ES2810303T3 (es) 2021-03-08
JP2019203014A (ja) 2019-11-28
EP3677282A1 (en) 2020-07-08
AU2019236602A1 (en) 2019-10-17
BR112018069974A2 (pt) 2019-01-29
EA202091849A1 (ru) 2020-12-11
CN108289961A (zh) 2018-07-17
US20220125767A1 (en) 2022-04-28
US20170281603A1 (en) 2017-10-05
EP3436074A1 (en) 2019-02-06
LT3436074T (lt) 2020-09-25
EA201891975A1 (ru) 2019-03-29
KR102136803B1 (ko) 2020-07-22
KR102233826B1 (ko) 2021-03-31
PT3436074T (pt) 2020-08-21
JP6567781B2 (ja) 2019-08-28
MX381896B (es) 2025-03-13
KR20180124970A (ko) 2018-11-21
IL262018A (en) 2018-10-31
US11135202B2 (en) 2021-10-05
ZA201806644B (en) 2021-02-24
CA3019326A1 (en) 2017-10-05
EA036505B1 (ru) 2020-11-18
DK3436074T3 (da) 2020-08-03
KR20180125552A (ko) 2018-11-23
PH12018502058A1 (en) 2019-06-24
EP3436074B1 (en) 2020-06-10
SG11201808453UA (en) 2018-10-30
CY1123221T1 (el) 2021-10-29
AU2017244145A1 (en) 2018-11-15
CA3113354A1 (en) 2017-10-05
KR20210035339A (ko) 2021-03-31
JP2019510044A (ja) 2019-04-11
CA3019326C (en) 2021-05-25
HUE050601T2 (hu) 2020-12-28
PL3436074T3 (pl) 2020-11-02
UA126114C2 (uk) 2022-08-17
AU2017244145B2 (en) 2019-08-01

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