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MX2021000395A - Composiciones senolíticas y usos de las mismas. - Google Patents

Composiciones senolíticas y usos de las mismas.

Info

Publication number
MX2021000395A
MX2021000395A MX2021000395A MX2021000395A MX2021000395A MX 2021000395 A MX2021000395 A MX 2021000395A MX 2021000395 A MX2021000395 A MX 2021000395A MX 2021000395 A MX2021000395 A MX 2021000395A MX 2021000395 A MX2021000395 A MX 2021000395A
Authority
MX
Mexico
Prior art keywords
diseases
disorders
prevented
treated
side effects
Prior art date
Application number
MX2021000395A
Other languages
English (en)
Inventor
Mark A Gallop
Marco Quarta
Julian Klein
Original Assignee
Rubedo Life Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rubedo Life Sciences Inc filed Critical Rubedo Life Sciences Inc
Publication of MX2021000395A publication Critical patent/MX2021000395A/es

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    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
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  • Endocrinology (AREA)

Abstract

En la presente se proporcionan agentes senolíticos para eliminar selectivamente células senescentes que se encuentran asociadas con numerosas patologías y enfermedades, incluidas patologías y enfermedades relacionadas con la edad. Como se describe en la presente, las enfermedades y trastornos asociados a células senescentes pueden tratarse o prevenirse mediante la administración de al menos un agente senolítico o composiciones farmacéuticas del mismo. Las enfermedades o trastornos asociados a las células senescentes tratados o prevenidos por los métodos descritos en la, presente incluyen, pero no se limitan a, enfermedades o trastornos cardiovasculares, enfermedades y trastornos cardiovasculares asociados con arteriosclerosis, tales como aterosclerosis, fibrosis pulmonar idiopática (IPF) enfermedad pulmonar obstructiva crónica (COPD), osteoartritis, enfermedades o trastornos inflamatorios, enfermedades o trastornos autoinmunes, enfermedades o trastornos pulmonares, enfermedades o trastornos neurológicos, enfermedades o trastornos dermatológicos, efectos secundarios de la quimioterapia, efectos secundarios de la radioterapia, metástasis y enfermedades metabólicas.
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