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MX2020014097A - Lipidos novedosos. - Google Patents

Lipidos novedosos.

Info

Publication number
MX2020014097A
MX2020014097A MX2020014097A MX2020014097A MX2020014097A MX 2020014097 A MX2020014097 A MX 2020014097A MX 2020014097 A MX2020014097 A MX 2020014097A MX 2020014097 A MX2020014097 A MX 2020014097A MX 2020014097 A MX2020014097 A MX 2020014097A
Authority
MX
Mexico
Prior art keywords
novel lipids
lipids
novel
present
invention includes
Prior art date
Application number
MX2020014097A
Other languages
English (en)
Inventor
Daniel Emil Levy
Annie Bouchard
James Mcchesney
Saravanan Kappusamy
John Kallikat Augustine
Original Assignee
Signpath Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Signpath Pharma Inc filed Critical Signpath Pharma Inc
Publication of MX2020014097A publication Critical patent/MX2020014097A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/091Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención incluye un compuesto que tiene la siguiente fórmula estructural: (ver Fórmula).
MX2020014097A 2018-06-26 2019-06-26 Lipidos novedosos. MX2020014097A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862690196P 2018-06-26 2018-06-26
US16/452,858 US10975111B2 (en) 2018-06-26 2019-06-26 Cardiopathy-reducing phosphodiester lipids
PCT/US2019/039162 WO2020006033A1 (en) 2018-06-26 2019-06-26 Novel lipids

Publications (1)

Publication Number Publication Date
MX2020014097A true MX2020014097A (es) 2021-04-13

Family

ID=68980509

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020014097A MX2020014097A (es) 2018-06-26 2019-06-26 Lipidos novedosos.
MX2023014281A MX2023014281A (es) 2018-06-26 2020-12-17 Lipidos novedosos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2023014281A MX2023014281A (es) 2018-06-26 2020-12-17 Lipidos novedosos.

Country Status (10)

Country Link
US (3) US10975111B2 (es)
EP (1) EP3813820A4 (es)
JP (2) JP7325840B2 (es)
KR (1) KR102627389B1 (es)
CN (1) CN112367986A (es)
AU (2) AU2019291808A1 (es)
CA (1) CA3103918C (es)
MX (2) MX2020014097A (es)
TW (1) TWI731336B (es)
WO (1) WO2020006033A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI731336B (zh) 2018-06-26 2021-06-21 美商標徑製藥公司 新穎脂質
US11344518B2 (en) 2018-08-14 2022-05-31 AltaThera Pharmaceuticals LLC Method of converting atrial fibrillation to normal sinus rhythm and loading oral sotalol in a shortened time frame
US11696902B2 (en) 2018-08-14 2023-07-11 AltaThera Pharmaceuticals, LLC Method of initiating and escalating sotalol hydrochloride dosing
US12396970B2 (en) 2021-08-20 2025-08-26 AltaThera Pharmaceuticals LLC Anti-arrhythmic compositions and methods
US10512620B1 (en) 2018-08-14 2019-12-24 AltaThera Pharmaceuticals, LLC Method of initiating and escalating sotalol hydrochloride dosing
US11610660B1 (en) 2021-08-20 2023-03-21 AltaThera Pharmaceuticals LLC Antiarrhythmic drug dosing methods, medical devices, and systems
CA3207493A1 (en) * 2021-01-29 2022-08-04 Signpath Pharma, Inc. Lipids that reduce lung damage, improve pulmonary function and decrease pro-inflammatory cytokines
KR20230147184A (ko) * 2021-03-03 2023-10-20 사인패스 파마 인코포레이티드 인간에서의 악성 흉막 삼출 치료
TW202417005A (zh) * 2022-09-22 2024-05-01 美商標徑製藥公司 保護心臟之脂質及使用方法
WO2025049064A2 (en) * 2023-08-28 2025-03-06 Signpath Pharma Inc. Cardioprotective lipids and methods of use

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005049587A1 (en) * 2003-11-21 2005-06-02 Ranbaxy Laboratories Limited Process for preparation of biphenyl tetrazole
EP1819715A4 (en) 2004-11-08 2010-02-17 Neopharm Inc SYNTHESIS OF CARDIOLIPINANALOGA AND APPLICATIONS THEREOF
US10117881B2 (en) * 2011-06-03 2018-11-06 Signpath Pharma, Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, LYSOPG and LYSOPC against drugs that cause channelopathies
ES2940564T3 (es) 2013-12-18 2023-05-09 Signpath Pharma Inc Mitigación liposómica de la inhibición inducida por fármaco del canal IKr cardíaco
ES2942132T3 (es) 2014-06-03 2023-05-30 Signpath Pharma Inc Efecto protector de DMPC, DMPG, DMPC/DMPG, EGPG, LYSOPG y LYSOPC frente a fármacos que provocan canalopatías
CN105273001A (zh) 2014-07-21 2016-01-27 南京绿叶制药有限公司 一种合成磷脂酰甘油单钠盐的方法
CN105985373A (zh) 2015-04-10 2016-10-05 江苏东南纳米材料有限公司 一种制备(r)-1,2-二脂肪酸甘油磷酯酰甘油酯的新方法
CN106188169B (zh) * 2016-07-07 2019-06-25 沈阳药科大学 一种含有唾液酸基团的脂质衍生物的合成及其在药物制剂中的应用
US20190008878A1 (en) * 2017-07-07 2019-01-10 Signpath Pharma Inc. Compositions and method for reducing cardiotoxicity
TWI731336B (zh) 2018-06-26 2021-06-21 美商標徑製藥公司 新穎脂質

Also Published As

Publication number Publication date
US11643424B2 (en) 2023-05-09
JP7325840B2 (ja) 2023-08-15
EP3813820A4 (en) 2022-05-04
TW202019404A (zh) 2020-06-01
KR102627389B1 (ko) 2024-01-19
AU2022205275B2 (en) 2024-05-30
US20210198294A1 (en) 2021-07-01
US20220056057A1 (en) 2022-02-24
WO2020006033A1 (en) 2020-01-02
KR20210018926A (ko) 2021-02-18
US20190389888A1 (en) 2019-12-26
AU2019291808A1 (en) 2021-01-14
CA3103918C (en) 2023-09-19
CN112367986A (zh) 2021-02-12
JP7646233B2 (ja) 2025-03-17
US11746119B2 (en) 2023-09-05
JP2021534076A (ja) 2021-12-09
MX2023014281A (es) 2024-01-17
AU2022205275A1 (en) 2022-08-11
JP2023153882A (ja) 2023-10-18
CA3103918A1 (en) 2020-01-02
EP3813820A1 (en) 2021-05-05
TWI731336B (zh) 2021-06-21
US10975111B2 (en) 2021-04-13

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