[go: up one dir, main page]

MX2020014058A - Celdas de flujo con guias de ondas lineales. - Google Patents

Celdas de flujo con guias de ondas lineales.

Info

Publication number
MX2020014058A
MX2020014058A MX2020014058A MX2020014058A MX2020014058A MX 2020014058 A MX2020014058 A MX 2020014058A MX 2020014058 A MX2020014058 A MX 2020014058A MX 2020014058 A MX2020014058 A MX 2020014058A MX 2020014058 A MX2020014058 A MX 2020014058A
Authority
MX
Mexico
Prior art keywords
nanowells
flowcells
linear waveguide
linear waveguides
grating
Prior art date
Application number
MX2020014058A
Other languages
English (en)
Inventor
Stanley S Hong
Geraint Evans
Original Assignee
Illumina Cambridge Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Cambridge Ltd filed Critical Illumina Cambridge Ltd
Publication of MX2020014058A publication Critical patent/MX2020014058A/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/42—Diffraction optics, i.e. systems including a diffractive element being designed for providing a diffractive effect
    • G02B27/4205—Diffraction optics, i.e. systems including a diffractive element being designed for providing a diffractive effect having a diffractive optical element [DOE] contributing to image formation, e.g. whereby modulation transfer function MTF or optical aberrations are relevant
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/42—Diffraction optics, i.e. systems including a diffractive element being designed for providing a diffractive effect
    • G02B27/4205—Diffraction optics, i.e. systems including a diffractive element being designed for providing a diffractive effect having a diffractive optical element [DOE] contributing to image formation, e.g. whereby modulation transfer function MTF or optical aberrations are relevant
    • G02B27/4227—Diffraction optics, i.e. systems including a diffractive element being designed for providing a diffractive effect having a diffractive optical element [DOE] contributing to image formation, e.g. whereby modulation transfer function MTF or optical aberrations are relevant in image scanning systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0851—Bottom walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0896—Nanoscaled
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6482—Sample cells, cuvettes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

Por ejemplo, una celda de flujo incluye: una capa de nanopocillos que tiene un primer conjunto de nanopocillos y un segundo conjunto de nanopocillos para recibir una muestra; una primera guía de ondas lineal asociada con el primer conjunto de nanopocillos, y una segunda guía de ondas lineal asociada con el segundo conjunto de nanopocillos; y una primera rejilla para la primera guía de ondas lineal, y una segunda rejilla para la segunda guía de ondas lineal, proporcionando la primera y segunda rejillas un acoplamiento diferencial de la primera luz y la segunda luz.
MX2020014058A 2019-06-28 2020-05-19 Celdas de flujo con guias de ondas lineales. MX2020014058A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962868423P 2019-06-28 2019-06-28
PCT/US2020/070063 WO2020264546A1 (en) 2019-06-28 2020-05-19 Flowcells with linear waveguides

Publications (1)

Publication Number Publication Date
MX2020014058A true MX2020014058A (es) 2021-05-27

Family

ID=74059625

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020014058A MX2020014058A (es) 2019-06-28 2020-05-19 Celdas de flujo con guias de ondas lineales.

Country Status (15)

Country Link
US (2) US11406977B2 (es)
EP (1) EP3990185B1 (es)
JP (1) JP7574084B2 (es)
KR (1) KR20220031482A (es)
CN (1) CN112703442A (es)
AU (1) AU2020289796A1 (es)
BR (1) BR112020026643A2 (es)
CA (1) CA3104755A1 (es)
IL (1) IL279566A (es)
MX (1) MX2020014058A (es)
MY (1) MY209672A (es)
SG (1) SG11202012996UA (es)
TW (1) TWI859247B (es)
WO (1) WO2020264546A1 (es)
ZA (1) ZA202007852B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020264546A1 (en) * 2019-06-28 2020-12-30 Illumina Cambridge Limited Flowcells with linear waveguides

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR19990014709A (ko) * 1995-05-12 1999-02-25 한스루돌프하우스 센서 플랫폼 및 감쇠 여기된 발광을 이용한 복수 분석물의병렬 검출 방법
ATE244883T1 (de) 1999-09-15 2003-07-15 Suisse Electronique Microtech Integriert-optischer sensor
JP4599019B2 (ja) 1999-12-17 2010-12-15 バイエル・テクノロジー・サービシーズ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング フローセル配列及び多重分析対象物測定のためのその利用
US6961490B2 (en) 2000-01-27 2005-11-01 Unaxis-Balzers Aktiengesellschaft Waveguide plate and process for its production and microtitre plate
AU2001281632A1 (en) 2000-08-09 2002-02-18 Artificial Sensing Instruments Asi Ag Waveguide grid array and optical measurement arrangement
US7070987B2 (en) 2000-10-30 2006-07-04 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7016560B2 (en) * 2001-02-28 2006-03-21 Lightwave Microsystems Corporation Microfluidic control for waveguide optical switches, variable attenuators, and other optical devices
US7233391B2 (en) 2003-11-21 2007-06-19 Perkinelmer Las, Inc. Optical device integrated with well
EP3415641B1 (en) 2004-09-17 2023-11-01 Pacific Biosciences Of California, Inc. Method for analysis of molecules
GB0507835D0 (en) 2005-04-18 2005-05-25 Solexa Ltd Method and device for nucleic acid sequencing using a planar wave guide
US7479404B2 (en) 2005-07-08 2009-01-20 The Board Of Trustees Of The University Of Illinois Photonic crystal biosensor structure and fabrication method
US9423397B2 (en) * 2006-03-10 2016-08-23 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
RU2422204C2 (ru) 2006-03-20 2011-06-27 Конинклейке Филипс Электроникс Н.В. Платформа система в корпусе для электронно-микрофлюидных устройств
WO2008028160A2 (en) * 2006-09-01 2008-03-06 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials
US8865078B2 (en) * 2010-06-11 2014-10-21 Industrial Technology Research Institute Apparatus for single-molecule detection
JP6548581B2 (ja) 2014-01-24 2019-07-24 技術研究組合光電子融合基盤技術研究所 グレーティングカプラ
EP2916125A1 (en) * 2014-03-07 2015-09-09 One Drop Diagnostics Sàrl Fluorescence-detected assays on microfluidic chips
MX383892B (es) * 2014-08-08 2025-03-14 Quantum Si Inc Sistema optico y circuito integrado de valoración para sondear, detectar y analizar moleculas.
CN104538841B (zh) * 2014-12-19 2017-12-22 武汉光迅科技股份有限公司 一种基于阵列波导光栅的混合集成外腔可调激光器
US10302972B2 (en) 2015-01-23 2019-05-28 Pacific Biosciences Of California, Inc. Waveguide transmission
WO2018013243A1 (en) 2016-06-01 2018-01-18 Quantum-Si Incorporated Integrated device for detecting and analyzing molecules
MX2019007070A (es) * 2016-12-16 2019-08-01 Quantum Si Inc Acoplador optico y sistema de guia de ondas.
DE102017211910A1 (de) 2017-07-12 2019-01-17 Dr. Johannes Heidenhain Gmbh Diffraktiver Biosensor
WO2020264546A1 (en) * 2019-06-28 2020-12-30 Illumina Cambridge Limited Flowcells with linear waveguides

Also Published As

Publication number Publication date
US20220105511A1 (en) 2022-04-07
CA3104755A1 (en) 2020-12-30
WO2020264546A1 (en) 2020-12-30
TW202118552A (zh) 2021-05-16
EP3990185A1 (en) 2022-05-04
US20220331798A1 (en) 2022-10-20
CN112703442A (zh) 2021-04-23
SG11202012996UA (en) 2021-02-25
BR112020026643A2 (pt) 2021-12-14
EP3990185A4 (en) 2023-05-31
MY209672A (en) 2025-07-30
JP7574084B2 (ja) 2024-10-28
US11406977B2 (en) 2022-08-09
IL279566A (en) 2021-03-01
JP2022538700A (ja) 2022-09-06
EP3990185B1 (en) 2024-09-11
ZA202007852B (en) 2024-04-24
TWI859247B (zh) 2024-10-21
US12053776B2 (en) 2024-08-06
KR20220031482A (ko) 2022-03-11
AU2020289796A1 (en) 2021-01-28

Similar Documents

Publication Publication Date Title
MX2021005723A (es) Enzima y sistema crispr-cas12j.
BR112017013680A2 (pt) sistema óptico
MX2010004910A (es) Anticuerpos monoclonales recombinantes y antigenos correspondientes para canceres colonico y pancreatico.
MX2019015848A (es) Cubetas de lectura.
SE0701556L (sv) Övergångsdel mellan två optiska vägledare
BR112016027743A2 (pt) Pigmento de efeito, e, método para produção de um pigmento de efeito
CO2021010089A2 (es) Portaobjetos y cubreobjetos impreso para identificar el plano focal de referencia para microscopía de luz
CO2023011463A2 (es) Nuevos anticuerpos anti-cd24
CO2019002607A2 (es) Biomarcadores de metabolitos para enfermedades asociadas con el sistema de activación por contacto
MX2020010808A (es) Receptor de antigeno quimerico especifico para el receptor de interleucina-23.
MX2021008216A (es) Anticuerpos anti-tigit.
MX2020014058A (es) Celdas de flujo con guias de ondas lineales.
MX2022000456A (es) Anticuerpos biespecificos simetricos tetravalentes.
MX2020000672A (es) Ensamble de conector de fibras.
CY1123245T1 (el) Εξομαλυμενη θαλασσια επιστρωση ανακλασης υπεριωδους ακτινοβολιας με χρωμα
CL2022000052A1 (es) Anticuerpos de pre–direccionamiento y metodos de uso
BR112018077135A2 (pt) elemento de guia de luz, sistema antibioincrustação, objeto, método para fornecer um sistema antibioincrustação, e método para prevenir e/ou reduzir a bioincrustação
MX2020011199A (es) Instrumentacion automatizada para la produccion de bibliotecas de peptidos de receptores de celulas t.
MX2021015637A (es) Sustrato que tiene una máscara de revestimiento combustible.
MX369720B (es) Sistema de iluminación para vehículo.
AR118354A1 (es) Métodos para producir composiciones de anticuerpos anti-tnf
PH12020552300A1 (en) Flowcells with linear waveguides
DE602005000298D1 (de) Steigerung der Anzahl der Kanäle auf Basis von Übergängen für optische Übertragungssysteme
BR112021019714A2 (pt) Manipulação de um anticorpo para ligação seletiva de tumor de cd47
CN104459850A (zh) 一种定向反光片