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MX2020004071A - Derivados de aztreonam y usos de los mismos. - Google Patents

Derivados de aztreonam y usos de los mismos.

Info

Publication number
MX2020004071A
MX2020004071A MX2020004071A MX2020004071A MX2020004071A MX 2020004071 A MX2020004071 A MX 2020004071A MX 2020004071 A MX2020004071 A MX 2020004071A MX 2020004071 A MX2020004071 A MX 2020004071A MX 2020004071 A MX2020004071 A MX 2020004071A
Authority
MX
Mexico
Prior art keywords
aztreonam derivatives
aztreonam
derivatives
empty
Prior art date
Application number
MX2020004071A
Other languages
English (en)
Inventor
John Freund
Eric M Gordon
Matthew A J Duncton
Original Assignee
Arixa Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arixa Pharmaceuticals Inc filed Critical Arixa Pharmaceuticals Inc
Publication of MX2020004071A publication Critical patent/MX2020004071A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/78—Halides of sulfonic acids
    • C07C309/79—Halides of sulfonic acids having halosulfonyl groups bound to acyclic carbon atoms
    • C07C309/82—Halides of sulfonic acids having halosulfonyl groups bound to acyclic carbon atoms of a carbon skeleton substituted by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

Se describen en la presente derivados de aztreonam, métodos terapéuticos de uso de los derivados de aztreonam, particulaimente en combinación con inhibidores de ß-Iactamasa, y composiciones farmacéuticas de los mismos. Los derivados de aztreonam pueden administrarse oralmente para proporcionar aztreonam biodisponible oralmente.
MX2020004071A 2017-10-02 2018-10-01 Derivados de aztreonam y usos de los mismos. MX2020004071A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762566909P 2017-10-02 2017-10-02
PCT/US2018/053778 WO2019070595A1 (en) 2017-10-02 2018-10-01 AZTREONAM DERIVATIVES AND USES THEREOF

Publications (1)

Publication Number Publication Date
MX2020004071A true MX2020004071A (es) 2020-07-28

Family

ID=63963503

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020004071A MX2020004071A (es) 2017-10-02 2018-10-01 Derivados de aztreonam y usos de los mismos.

Country Status (12)

Country Link
US (3) US10280161B2 (es)
EP (1) EP3676247B8 (es)
JP (1) JP6991345B2 (es)
KR (1) KR102455390B1 (es)
CN (1) CN111448182A (es)
AU (1) AU2018345321B2 (es)
BR (1) BR112020006594A2 (es)
CA (1) CA3077474A1 (es)
IL (1) IL273571A (es)
MX (1) MX2020004071A (es)
SG (1) SG11202002300QA (es)
WO (1) WO2019070595A1 (es)

Families Citing this family (9)

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KR102455390B1 (ko) 2017-10-02 2022-10-17 아릭사 파마슈티컬스 인코포레이티드 아즈트레오남 유도체 및 이의 용도
JP7437847B2 (ja) 2018-10-01 2024-02-26 アリクサ ファーマシューティカルズ、インコーポレイテッド レレバクタムの誘導体およびその使用
CN113614084A (zh) 2019-03-12 2021-11-05 阿里萨制药公司 阿维巴坦衍生物的晶型
US11565999B2 (en) 2019-04-25 2023-01-31 Arixa Pharmaceuticals, Inc. Methods of synthesizing aztreonam derivatives
JP7673052B2 (ja) 2019-08-29 2025-05-08 アリクサ ファーマシューティカルズ、インコーポレイテッド 細菌感染症を処置するためのベータラクタム抗生物質およびアビバクタム誘導体の経口投与される組合せ
CN112047840A (zh) * 2020-08-31 2020-12-08 山东药品食品职业学院 一种7-溴-2,2-二甲基庚酸乙酯的合成方法及合成得到的产品
CN112661716A (zh) * 2020-12-31 2021-04-16 山东金城柯瑞化学有限公司 一种三苯甲基氨噻肟酸的制备方法
CN115448920B (zh) * 2022-10-14 2025-01-03 广州楷石医药有限公司 一种β-内酰胺酶抑制剂及其应用
CN118561730B (zh) * 2024-07-03 2024-11-22 北京世纪迈劲生物科技有限公司 一种氨曲南主环中间体的制备方法

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Also Published As

Publication number Publication date
SG11202002300QA (en) 2020-04-29
CA3077474A1 (en) 2019-04-11
US20210009580A1 (en) 2021-01-14
US10815228B2 (en) 2020-10-27
AU2018345321A1 (en) 2020-04-16
JP6991345B2 (ja) 2022-01-12
US20190211006A1 (en) 2019-07-11
EP3676247A1 (en) 2020-07-08
KR20200060490A (ko) 2020-05-29
KR102455390B1 (ko) 2022-10-17
US10280161B2 (en) 2019-05-07
EP3676247B8 (en) 2023-04-12
IL273571A (en) 2020-05-31
JP2020536122A (ja) 2020-12-10
WO2019070595A1 (en) 2019-04-11
EP3676247B1 (en) 2023-03-08
US20190100516A1 (en) 2019-04-04
BR112020006594A2 (pt) 2020-12-15
CN111448182A (zh) 2020-07-24
AU2018345321B2 (en) 2021-05-20

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