MX2020000090A - Composiciones y metodos para tratar o prevenir la taquicardia ventricular polimorfica catecolaminergica. - Google Patents
Composiciones y metodos para tratar o prevenir la taquicardia ventricular polimorfica catecolaminergica.Info
- Publication number
- MX2020000090A MX2020000090A MX2020000090A MX2020000090A MX2020000090A MX 2020000090 A MX2020000090 A MX 2020000090A MX 2020000090 A MX2020000090 A MX 2020000090A MX 2020000090 A MX2020000090 A MX 2020000090A MX 2020000090 A MX2020000090 A MX 2020000090A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- methods
- treating
- preventing
- ventricular tachycardia
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 201000000015 catecholaminergic polymorphic ventricular tachycardia Diseases 0.000 title abstract 2
- 210000004413 cardiac myocyte Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000008602 contraction Effects 0.000 abstract 1
- 210000004263 induced pluripotent stem cell Anatomy 0.000 abstract 1
- 230000002107 myocardial effect Effects 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
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- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5061—Muscle cells
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- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
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Abstract
La presente invención presenta composiciones de péptidos y polinucleótidos AIP, métodos para usar tales composiciones para el tratamiento de la CPVT, así como un modelo de cardiomiocito derivado de células madre pluripotentes inducidas humanas, útil para caracterizar agentes que modulen la conducción y contracción del miocardio.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762529256P | 2017-07-06 | 2017-07-06 | |
| PCT/US2018/041043 WO2019010386A1 (en) | 2017-07-06 | 2018-07-06 | COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF CATECHOLAMINERGIC POLYMORPH VENTRICULAR TACHYCARDIA RELATED DISORDERS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2020000090A true MX2020000090A (es) | 2020-08-06 |
Family
ID=64950369
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020000090A MX2020000090A (es) | 2017-07-06 | 2018-07-06 | Composiciones y metodos para tratar o prevenir la taquicardia ventricular polimorfica catecolaminergica. |
| MX2025005101A MX2025005101A (es) | 2017-07-06 | 2020-01-08 | Composiciones y metodos para tratar o prevenir la taquicardia ventricular polimorfica catecolaminergica |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2025005101A MX2025005101A (es) | 2017-07-06 | 2020-01-08 | Composiciones y metodos para tratar o prevenir la taquicardia ventricular polimorfica catecolaminergica |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20210147497A1 (es) |
| EP (1) | EP3648755A4 (es) |
| JP (2) | JP2020532492A (es) |
| KR (2) | KR20200027521A (es) |
| CN (1) | CN111194212A (es) |
| AU (2) | AU2018297171B2 (es) |
| BR (1) | BR112020000258A2 (es) |
| CA (1) | CA3069127A1 (es) |
| CO (1) | CO2020005617A2 (es) |
| EA (1) | EA202090231A1 (es) |
| IL (1) | IL271823A (es) |
| MX (2) | MX2020000090A (es) |
| SG (1) | SG11202000007PA (es) |
| WO (1) | WO2019010386A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114105916B (zh) * | 2021-11-25 | 2023-04-18 | 深圳大学 | 一种RyR2稳定剂及其制备方法、相应的药用组合物和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040048780A1 (en) * | 2000-05-10 | 2004-03-11 | The Trustees Of Columbia University In The City Of New York | Method for treating and preventing cardiac arrhythmia |
| US7704990B2 (en) * | 2005-08-25 | 2010-04-27 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
| WO2009042906A1 (en) * | 2007-09-26 | 2009-04-02 | Regents Of The University Of Colorado | Compositions and methods for camkii inhibitors and uses thereof |
| SG192305A1 (en) * | 2012-01-20 | 2013-08-30 | Singapore Health Serv Pte Ltd | Induced pluripotent stem cell (ipsc)-derived cardiomyocyte-like cells and uses thereof in screening for agents |
| WO2014138212A1 (en) * | 2013-03-06 | 2014-09-12 | Allosteros Therapeutics, Inc. | CaMKII INHIBITORS AND USES THEREOF |
| WO2016168694A1 (en) * | 2015-04-15 | 2016-10-20 | Ohio State Innovation Foundation | Engineered calmodulin for treatment of ryanopathies |
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2018
- 2018-07-06 MX MX2020000090A patent/MX2020000090A/es unknown
- 2018-07-06 EA EA202090231A patent/EA202090231A1/ru unknown
- 2018-07-06 BR BR112020000258-5A patent/BR112020000258A2/pt unknown
- 2018-07-06 KR KR1020207003056A patent/KR20200027521A/ko not_active Ceased
- 2018-07-06 WO PCT/US2018/041043 patent/WO2019010386A1/en not_active Ceased
- 2018-07-06 KR KR1020247019924A patent/KR20240103036A/ko active Pending
- 2018-07-06 JP JP2020500044A patent/JP2020532492A/ja active Pending
- 2018-07-06 US US16/628,162 patent/US20210147497A1/en active Pending
- 2018-07-06 AU AU2018297171A patent/AU2018297171B2/en active Active
- 2018-07-06 CN CN201880058071.3A patent/CN111194212A/zh active Pending
- 2018-07-06 SG SG11202000007PA patent/SG11202000007PA/en unknown
- 2018-07-06 CA CA3069127A patent/CA3069127A1/en active Pending
- 2018-07-06 EP EP18827460.9A patent/EP3648755A4/en active Pending
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2020
- 2020-01-02 IL IL271823A patent/IL271823A/en unknown
- 2020-01-08 MX MX2025005101A patent/MX2025005101A/es unknown
- 2020-05-05 CO CONC2020/0005617A patent/CO2020005617A2/es unknown
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2024
- 2024-04-02 JP JP2024059501A patent/JP2024081764A/ja active Pending
- 2024-09-17 AU AU2024219780A patent/AU2024219780A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2024219780A1 (en) | 2024-10-10 |
| KR20240103036A (ko) | 2024-07-03 |
| AU2018297171A1 (en) | 2020-01-30 |
| IL271823A (en) | 2020-02-27 |
| EA202090231A1 (ru) | 2020-06-08 |
| CO2020005617A2 (es) | 2020-07-31 |
| WO2019010386A1 (en) | 2019-01-10 |
| EP3648755A4 (en) | 2021-10-20 |
| CA3069127A1 (en) | 2019-01-10 |
| MX2025005101A (es) | 2025-06-02 |
| JP2020532492A (ja) | 2020-11-12 |
| SG11202000007PA (en) | 2020-01-30 |
| KR20200027521A (ko) | 2020-03-12 |
| CN111194212A (zh) | 2020-05-22 |
| BR112020000258A2 (pt) | 2020-07-14 |
| AU2018297171B2 (en) | 2024-09-19 |
| US20210147497A1 (en) | 2021-05-20 |
| EP3648755A1 (en) | 2020-05-13 |
| JP2024081764A (ja) | 2024-06-18 |
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