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MX2019015681A - Derivados de pirido-imidazo rifamicina como agente antibacteriano. - Google Patents

Derivados de pirido-imidazo rifamicina como agente antibacteriano.

Info

Publication number
MX2019015681A
MX2019015681A MX2019015681A MX2019015681A MX2019015681A MX 2019015681 A MX2019015681 A MX 2019015681A MX 2019015681 A MX2019015681 A MX 2019015681A MX 2019015681 A MX2019015681 A MX 2019015681A MX 2019015681 A MX2019015681 A MX 2019015681A
Authority
MX
Mexico
Prior art keywords
pyrido
antibacterial agent
rifamycin derivatives
imidazo rifamycin
imidazo
Prior art date
Application number
MX2019015681A
Other languages
English (en)
Other versions
MX386622B (es
Inventor
Marchi Egidio
Lapini Sacchetti Alessandro
Ori Claudia
PRETI Lisa
Original Assignee
Biofer Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT102017000091912A external-priority patent/IT201700091912A1/it
Application filed by Biofer Spa filed Critical Biofer Spa
Publication of MX2019015681A publication Critical patent/MX2019015681A/es
Publication of MX386622B publication Critical patent/MX386622B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente invención se refiere a pirido-imidazo rifamicinas novedosas, caracterizadas por una actividad antibacteriana altamente selectiva y baja absorción por vía oral.
MX2019015681A 2017-06-26 2018-06-25 Derivados de pirido-imidazo rifamicina como agente antibacteriano MX386622B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17177894 2017-06-26
IT102017000091912A IT201700091912A1 (it) 2017-08-08 2017-08-08 Nuove pirido-imidazo rifamicine
PCT/IB2018/054645 WO2019003076A1 (en) 2017-06-26 2018-06-25 PYRIDO-IMIDAZO-RIFAMYCIN DERIVATIVES AS ANTIBACTERIAL AGENT

Publications (2)

Publication Number Publication Date
MX2019015681A true MX2019015681A (es) 2020-02-26
MX386622B MX386622B (es) 2025-03-19

Family

ID=64742822

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019015681A MX386622B (es) 2017-06-26 2018-06-25 Derivados de pirido-imidazo rifamicina como agente antibacteriano

Country Status (10)

Country Link
US (2) US11028086B2 (es)
EP (1) EP3645539B1 (es)
CN (1) CN110770244A (es)
DK (1) DK3645539T3 (es)
ES (1) ES2868180T3 (es)
HU (1) HUE054832T2 (es)
MX (1) MX386622B (es)
PL (1) PL3645539T3 (es)
RU (1) RU2020102511A (es)
WO (1) WO2019003076A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1698630B1 (en) 2005-03-03 2014-09-03 ALFA WASSERMANN S.p.A. New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations
HUE054832T2 (hu) 2017-06-26 2021-10-28 Biofer Spa Pirido-imidazo rifamicinszármazékok baktériumellenes szerként
JP2025536245A (ja) * 2022-10-05 2025-11-05 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 非結核性マイコバクテリアに対するリファマイシン

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1090759B (it) 1977-11-29 1985-06-26 Alfa Farmaceutici Spa Procedimento per la preparazione di 3 iodio e 3 bromo rifamicina s
IT1154655B (it) * 1980-05-22 1987-01-21 Alfa Farmaceutici Spa Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica
IT1199374B (it) * 1984-05-15 1988-12-30 Alfa Farmaceutici Spa Processo per la preparazione di pirido-imidazo-rifamicine
ITMI20032144A1 (it) 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
US7250413B2 (en) * 2004-04-26 2007-07-31 Cumbre Pharmaceuticals Inc. C-25 carbamate rifamycin derivatives with activity against drug-resistant microbes
EP1698630B1 (en) 2005-03-03 2014-09-03 ALFA WASSERMANN S.p.A. New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations
BRPI0614758A2 (pt) * 2005-08-11 2011-04-12 Targanta Therapeutics Inc rifamicinas fosfonadas e usos destas para a prevenção e tratamento de infecções na articulação e osso
IT1397617B1 (it) * 2009-04-20 2013-01-18 Alfa Wassermann Spa Nuovi derivati della rifamicina
JP6400580B2 (ja) * 2012-08-13 2018-10-03 アディファルム・エアドゥ ３−ホルミルリファマイシンｓｖ及び３−ホルミルリファマイシンｓの３−（４−シンナミル−１−ピペラジニル）アミノ誘導体を含有する医薬製剤並びにこれらの製造方法
HUE054832T2 (hu) 2017-06-26 2021-10-28 Biofer Spa Pirido-imidazo rifamicinszármazékok baktériumellenes szerként

Also Published As

Publication number Publication date
RU2020102511A3 (es) 2021-07-27
EP3645539A1 (en) 2020-05-06
CN110770244A (zh) 2020-02-07
EP3645539B1 (en) 2021-04-07
RU2020102511A (ru) 2021-07-27
ES2868180T3 (es) 2021-10-21
HUE054832T2 (hu) 2021-10-28
US11028086B2 (en) 2021-06-08
PL3645539T3 (pl) 2021-10-25
DK3645539T3 (da) 2021-05-10
WO2019003076A1 (en) 2019-01-03
MX386622B (es) 2025-03-19
US20210363143A1 (en) 2021-11-25
US20200157104A1 (en) 2020-05-21

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