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MX2019015316A - Aseguramiento de la calidad de condrocitos. - Google Patents

Aseguramiento de la calidad de condrocitos.

Info

Publication number
MX2019015316A
MX2019015316A MX2019015316A MX2019015316A MX2019015316A MX 2019015316 A MX2019015316 A MX 2019015316A MX 2019015316 A MX2019015316 A MX 2019015316A MX 2019015316 A MX2019015316 A MX 2019015316A MX 2019015316 A MX2019015316 A MX 2019015316A
Authority
MX
Mexico
Prior art keywords
chondrocytes
chondrocytic
quality assurance
degree
composition
Prior art date
Application number
MX2019015316A
Other languages
English (en)
Inventor
Åkerlund Evy Lundgren
Masoumi Katarzyna Chmielarska
Original Assignee
Xintela Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xintela Ab filed Critical Xintela Ab
Publication of MX2019015316A publication Critical patent/MX2019015316A/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/58—Adhesion molecules, e.g. ICAM, VCAM, CD18 (ligand), CD11 (ligand), CD49 (ligand)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/585—Integrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/00—3D culture
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70546—Integrin superfamily, e.g. VLAs, leuCAM, GPIIb/GPIIIa, LPAM

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Signal Processing For Digital Recording And Reproducing (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Paper (AREA)

Abstract

La presente invención se refiere a métodos que están basados en la expresión de integrina alfa10 e integrina alfa11 en condrocitos, utilizados para determinar la pureza, calidad, grado de identidad condrocítica, potencia condrocítica, y/o grado de fenotipo condrocítico de una composición que comprende condrocitos, así como para aislar y enriquecer una población de condrocitos de alta calidad y controlar el cultivo y expansión de los condrocitos de alta calidad. La presente invención también se refiere a composición que comprende condrocitos.
MX2019015316A 2017-06-29 2018-06-29 Aseguramiento de la calidad de condrocitos. MX2019015316A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE1750849 2017-06-29
PCT/EP2018/067580 WO2019002547A1 (en) 2017-06-29 2018-06-29 QUALITY ASSURANCE OF CHONDROCYTES

Publications (1)

Publication Number Publication Date
MX2019015316A true MX2019015316A (es) 2020-07-20

Family

ID=62784172

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019015316A MX2019015316A (es) 2017-06-29 2018-06-29 Aseguramiento de la calidad de condrocitos.

Country Status (13)

Country Link
US (3) US10781424B2 (es)
EP (1) EP3510142A1 (es)
JP (2) JP7199724B2 (es)
KR (1) KR102709894B1 (es)
CN (1) CN111032859B (es)
AU (1) AU2018294532B2 (es)
BR (1) BR112019024558A2 (es)
CA (1) CA3067109A1 (es)
IL (1) IL271634B2 (es)
MX (1) MX2019015316A (es)
SG (1) SG11201910695QA (es)
TW (1) TWI810192B (es)
WO (1) WO2019002547A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3417888A1 (de) * 2017-06-25 2018-12-26 co.don AG Verfahren zum herstellen von transplantierbarem knorpelgewebe
CN113791222B (zh) * 2021-09-17 2024-04-19 南华大学 一种d-核糖快速诱导的人肌红蛋白非酶糖基化位点的鉴定方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1068238B1 (en) * 1998-04-02 2012-10-03 Xintela AB An integrin heterodimer and a subunit thereof
JP5064025B2 (ja) * 2003-04-14 2012-10-31 キシンテラ、アクチボラグ インテグリンα１０β１を結合することができる新規モノクローナル抗体
WO2005001079A2 (en) 2003-06-27 2005-01-06 Ethicon, Incorporated Soft tissue repair and regeneration using postpartum-derived cells
EP1996698A1 (en) * 2006-03-01 2008-12-03 Cartela R&D AB Expansion and differentiation of mesenchymal stem cells
CA2734446C (en) 2008-08-22 2017-06-20 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
KR102571075B1 (ko) * 2015-02-16 2023-08-25 타르진타 아베 Cns에서 악성 종양의 검출 및 치료

Also Published As

Publication number Publication date
JP2023039995A (ja) 2023-03-22
CN111032859B (zh) 2024-02-27
US20200377858A1 (en) 2020-12-03
US10781424B2 (en) 2020-09-22
IL271634A (en) 2020-02-27
KR20200022378A (ko) 2020-03-03
CN111032859A (zh) 2020-04-17
IL271634B1 (en) 2024-05-01
US20230348857A1 (en) 2023-11-02
TW201907004A (zh) 2019-02-16
AU2018294532B2 (en) 2025-02-20
IL271634B2 (en) 2024-09-01
AU2018294532A1 (en) 2020-02-13
WO2019002547A9 (en) 2019-05-31
KR102709894B1 (ko) 2024-09-24
US11725188B2 (en) 2023-08-15
US20190300855A1 (en) 2019-10-03
WO2019002547A1 (en) 2019-01-03
BR112019024558A2 (pt) 2020-06-09
JP2020525414A (ja) 2020-08-27
US12247222B2 (en) 2025-03-11
TWI810192B (zh) 2023-08-01
CA3067109A1 (en) 2019-01-03
SG11201910695QA (en) 2020-01-30
JP7199724B2 (ja) 2023-01-06
EP3510142A1 (en) 2019-07-17

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