MX2019015283A - Dispositivos difusores de luz para su uso en fotoimmunoterapia. - Google Patents
Dispositivos difusores de luz para su uso en fotoimmunoterapia.Info
- Publication number
- MX2019015283A MX2019015283A MX2019015283A MX2019015283A MX2019015283A MX 2019015283 A MX2019015283 A MX 2019015283A MX 2019015283 A MX2019015283 A MX 2019015283A MX 2019015283 A MX2019015283 A MX 2019015283A MX 2019015283 A MX2019015283 A MX 2019015283A
- Authority
- MX
- Mexico
- Prior art keywords
- core
- light
- fiber
- diffusing
- section
- Prior art date
Links
- 239000000835 fiber Substances 0.000 abstract 6
- 239000013307 optical fiber Substances 0.000 abstract 2
- 230000000903 blocking effect Effects 0.000 abstract 1
- 238000009792 diffusion process Methods 0.000 abstract 1
- 230000003595 spectral effect Effects 0.000 abstract 1
Classifications
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/0001—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings specially adapted for lighting devices or systems
- G02B6/0005—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings specially adapted for lighting devices or systems the light guides being of the fibre type
- G02B6/0008—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings specially adapted for lighting devices or systems the light guides being of the fibre type the light being emitted at the end of the fibre
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/067—Radiation therapy using light using laser light
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
- G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
- G02B23/2407—Optical details
- G02B23/2461—Illumination
- G02B23/2469—Illumination using optical fibres
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
- G02B27/09—Beam shaping, e.g. changing the cross-sectional area, not otherwise provided for
- G02B27/0927—Systems for changing the beam intensity distribution, e.g. Gaussian to top-hat
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B5/00—Optical elements other than lenses
- G02B5/02—Diffusing elements; Afocal elements
- G02B5/0205—Diffusing elements; Afocal elements characterised by the diffusing properties
- G02B5/021—Diffusing elements; Afocal elements characterised by the diffusing properties the diffusion taking place at the element's surface, e.g. by means of surface roughening or microprismatic structures
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/0001—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings specially adapted for lighting devices or systems
- G02B6/0005—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings specially adapted for lighting devices or systems the light guides being of the fibre type
- G02B6/001—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings specially adapted for lighting devices or systems the light guides being of the fibre type the light being emitted along at least a portion of the lateral surface of the fibre
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/02—Optical fibres with cladding with or without a coating
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/02—Optical fibres with cladding with or without a coating
- G02B6/02295—Microstructured optical fibre
- G02B6/02314—Plurality of longitudinal structures extending along optical fibre axis, e.g. holes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/02—Optical fibres with cladding with or without a coating
- G02B6/036—Optical fibres with cladding with or without a coating core or cladding comprising multiple layers
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/24—Coupling light guides
- G02B6/26—Optical coupling means
- G02B6/262—Optical details of coupling light into, or out of, or between fibre ends, e.g. special fibre end shapes or associated optical elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B2018/2035—Beam shaping or redirecting; Optical components therefor
- A61B2018/20554—Arrangements for particular intensity distribution, e.g. tophat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
- A61N2005/0612—Apparatus for use inside the body using probes penetrating tissue; interstitial probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/063—Radiation therapy using light comprising light transmitting means, e.g. optical fibres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0664—Details
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B5/00—Optical elements other than lenses
- G02B5/02—Diffusing elements; Afocal elements
- G02B5/0205—Diffusing elements; Afocal elements characterised by the diffusing properties
- G02B5/021—Diffusing elements; Afocal elements characterised by the diffusing properties the diffusion taking place at the element's surface, e.g. by means of surface roughening or microprismatic structures
- G02B5/0221—Diffusing elements; Afocal elements characterised by the diffusing properties the diffusion taking place at the element's surface, e.g. by means of surface roughening or microprismatic structures the surface having an irregular structure
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B5/00—Optical elements other than lenses
- G02B5/02—Diffusing elements; Afocal elements
- G02B5/0205—Diffusing elements; Afocal elements characterised by the diffusing properties
- G02B5/021—Diffusing elements; Afocal elements characterised by the diffusing properties the diffusion taking place at the element's surface, e.g. by means of surface roughening or microprismatic structures
- G02B5/0226—Diffusing elements; Afocal elements characterised by the diffusing properties the diffusion taking place at the element's surface, e.g. by means of surface roughening or microprismatic structures having particles on the surface
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/24—Coupling light guides
- G02B6/241—Light guide terminations
Landscapes
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Astronomy & Astrophysics (AREA)
- Light Guides In General And Applications Therefor (AREA)
- Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
- Optical Couplings Of Light Guides (AREA)
- Radiation-Therapy Devices (AREA)
- Artificial Filaments (AREA)
- Absorbent Articles And Supports Therefor (AREA)
Abstract
La presente invención proporciona un dispositivo difusor de luz cilíndrico (300) que comprende una fibra de núcleo no circular (302) que tiene (i) un núcleo de la fibra (350) que proporciona una distribución de irradiancia del núcleo de "sombrero de copa"; opcionalmente (ii) un medio de bloqueo de luz (314) que evitan la emisión de luz frontal desde extremo distal de la fibra de núcleo no circular (302); y (iii) una sección difusora de luz (308) que tiene un extremo proximal difusor (310), un extremo distal difusor (312) y características de dispersión interna(362) distribuidas dentro del núcleo de la fibra (350) de la sección difusora de luz (308) a lo largo del eje central (364) del núcleo de la fibra (350), en donde la sección difusión de la luz (308) emite irradiancia en una distribución de irradiancia difusora radialmente simétrica longitudinalmente de "sombrero de copa". La descripción también proporciona un dispositivo (600) que comprende una sección de fibra de núcleo no circular (604) y una lente (606), en donde la sección núcleo no circular tiene una distribución de irradiancia del núcleo de "sombrero de copa" y el dispositivo proporciona una distribución de irradiancia espectral "de sombrero de copa" en una ubicación focalizada. La descripción también proporciona un dispositivo (700) que comprende una fibra óptica (702) y un conjunto de lentes de colimación (704) que incluye una abertura variable (714) que bloquea porciones de la luz descompuestas de la fibra óptica permitiendo de esta manera que solo una porción central de la luz salga de la abertura variable que da como resultado una distribución de irradiancia plana.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662412606P | 2016-10-25 | 2016-10-25 | |
| US201762529507P | 2017-07-07 | 2017-07-07 | |
| PCT/US2017/057787 WO2018080952A1 (en) | 2016-10-25 | 2017-10-23 | Light diffusing devices for use in photoimmunotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019015283A true MX2019015283A (es) | 2020-02-13 |
| MX376819B MX376819B (es) | 2025-03-07 |
Family
ID=60473584
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019015283A MX376819B (es) | 2016-10-25 | 2017-10-23 | Dispositivos difusores de luz para su uso en fotoimmunoterapia |
| MX2019015282A MX376820B (es) | 2016-10-25 | 2017-10-23 | Dispositivos difusores de luz para su uso en fotoimmunoterapia |
| MX2019004391A MX371235B (es) | 2016-10-25 | 2017-10-23 | Dispositivos difusores de luz para su uso en fotoimmunoterapia |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019015282A MX376820B (es) | 2016-10-25 | 2017-10-23 | Dispositivos difusores de luz para su uso en fotoimmunoterapia |
| MX2019004391A MX371235B (es) | 2016-10-25 | 2017-10-23 | Dispositivos difusores de luz para su uso en fotoimmunoterapia |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US10527771B2 (es) |
| EP (2) | EP3532771A1 (es) |
| JP (3) | JP6688940B2 (es) |
| KR (3) | KR102103127B1 (es) |
| CN (2) | CN111035858B (es) |
| AU (3) | AU2017351052B2 (es) |
| BR (2) | BR122020013058B1 (es) |
| CA (3) | CA3070469C (es) |
| MX (3) | MX376819B (es) |
| RU (2) | RU2740793C2 (es) |
| SG (2) | SG11201903062TA (es) |
| WO (1) | WO2018080952A1 (es) |
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| US8524239B2 (en) | 2010-07-09 | 2013-09-03 | The United States of America as represented by the Secrectary, Department of Health and Human Services | Photosensitizing antibody-fluorophore conjugates |
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| CN121270700A (zh) | 2015-08-07 | 2026-01-06 | 美国政府(由卫生和人类服务部的部长所代表) | 用于治疗癌症的针对抑制细胞的近红外光免疫疗法(nir-pit) |
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| JP7085995B2 (ja) | 2015-08-18 | 2022-06-17 | ラクテン・メディカル,インコーポレイテッド | 光免疫療法のための組成物、組み合わせおよび関連方法 |
| MX376819B (es) | 2016-10-25 | 2025-03-07 | Rakuten Medical Inc | Dispositivos difusores de luz para su uso en fotoimmunoterapia |
| EP3706655B1 (en) * | 2017-11-10 | 2024-07-24 | Boston Scientific Scimed, Inc. | Medical laser fiber |
| KR102854858B1 (ko) | 2018-06-01 | 2025-09-03 | 라쿠텐 메디칼, 인크. | 프탈로시아닌 염료 접합체 조성물 |
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| JP2022546546A (ja) | 2019-09-03 | 2022-11-04 | ラクテン・メディカル,インコーポレイテッド | フタロシアニン色素-ターゲティング分子コンジュゲートを使用する処置のための方法 |
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- 2017-10-23 BR BR122020013058-0A patent/BR122020013058B1/pt active IP Right Grant
- 2017-10-23 CN CN201911310538.1A patent/CN111035858B/zh not_active Expired - Fee Related
- 2017-10-23 EP EP17804677.7A patent/EP3532771A1/en not_active Withdrawn
- 2017-10-23 SG SG11201903062TA patent/SG11201903062TA/en unknown
- 2017-10-23 RU RU2019140000A patent/RU2740793C2/ru active
- 2017-10-23 KR KR1020197011851A patent/KR102103127B1/ko not_active Expired - Fee Related
- 2017-10-23 US US15/790,110 patent/US10527771B2/en active Active
- 2017-10-23 CA CA3070469A patent/CA3070469C/en active Active
- 2017-10-23 BR BR112019008189A patent/BR112019008189A2/pt not_active Application Discontinuation
- 2017-10-23 WO PCT/US2017/057787 patent/WO2018080952A1/en not_active Ceased
- 2017-10-23 CN CN201780065396.XA patent/CN109863346A/zh active Pending
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