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MX2019013634A - Composiciones y metodos para tratar cancer con mutaciones de braf atipicas. - Google Patents

Composiciones y metodos para tratar cancer con mutaciones de braf atipicas.

Info

Publication number
MX2019013634A
MX2019013634A MX2019013634A MX2019013634A MX2019013634A MX 2019013634 A MX2019013634 A MX 2019013634A MX 2019013634 A MX2019013634 A MX 2019013634A MX 2019013634 A MX2019013634 A MX 2019013634A MX 2019013634 A MX2019013634 A MX 2019013634A
Authority
MX
Mexico
Prior art keywords
methods
compositions
treating cancer
atypical
braf mutations
Prior art date
Application number
MX2019013634A
Other languages
English (en)
Inventor
Saha Saurabh
Decrescenzo Gary
WELSCH Dean
Original Assignee
Biomed Valley Discoveries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomed Valley Discoveries Inc filed Critical Biomed Valley Discoveries Inc
Publication of MX2019013634A publication Critical patent/MX2019013634A/es

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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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Abstract

La presente invención se refiere a, entre otros, métodos, composiciones farmacéuticas, y kits para tratar o aliviar los efectos de un cáncer en un sujeto, el cual alberga una mutación de BRAF atípica (es decir, una mutación de BRAF no V600E/K), que comprende un inhibidor de ERK. También se proporcionan métodos para identificar un sujeto que tiene un cáncer mutante de BRAF atípico quién podría beneficiarse de la terapia que comprende un inhibidor de ERK.
MX2019013634A 2017-05-16 2018-05-15 Composiciones y metodos para tratar cancer con mutaciones de braf atipicas. MX2019013634A (es)

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CN110799245B (zh) 2022-08-09
US20210085663A1 (en) 2021-03-25
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EP3624896A1 (en) 2020-03-25
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JP7405408B2 (ja) 2023-12-26
CA3063614A1 (en) 2018-11-22
RU2019141300A (ru) 2021-06-16
WO2018213302A1 (en) 2018-11-22
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