MX2019012260A - Metodos de analisis mutacional y de metilacion del adn para vigilancia del cancer de vejiga. - Google Patents
Metodos de analisis mutacional y de metilacion del adn para vigilancia del cancer de vejiga.Info
- Publication number
- MX2019012260A MX2019012260A MX2019012260A MX2019012260A MX2019012260A MX 2019012260 A MX2019012260 A MX 2019012260A MX 2019012260 A MX2019012260 A MX 2019012260A MX 2019012260 A MX2019012260 A MX 2019012260A MX 2019012260 A MX2019012260 A MX 2019012260A
- Authority
- MX
- Mexico
- Prior art keywords
- bladder cancer
- dna methylation
- analysis methods
- mutational analysis
- cancer surveillance
- Prior art date
Links
- 206010005003 Bladder cancer Diseases 0.000 title abstract 3
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 title abstract 3
- 201000005112 urinary bladder cancer Diseases 0.000 title abstract 3
- 238000004458 analytical method Methods 0.000 title abstract 2
- 230000007067 DNA methylation Effects 0.000 title 1
- 230000000869 mutational effect Effects 0.000 title 1
- 206010064571 Gene mutation Diseases 0.000 abstract 1
- 230000002596 correlated effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 239000013610 patient sample Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7023—(Hyper)proliferation
- G01N2800/7028—Cancer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
La presente descripción se refiere a métodos para verificar pacientes con cáncer de vejiga y analizar muestras de pacientes para detectar la presencia de ADN metilado y opcionalmente mutaciones genéticas particulares. En algunas modalidades, los resultados del análisis son correlacionados con mediciones de resultados clínicos tales como el riesgo de recurrencia del cáncer de vejiga.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762508274P | 2017-05-18 | 2017-05-18 | |
| PCT/US2018/033146 WO2018213550A1 (en) | 2017-05-18 | 2018-05-17 | Dna methylation and mutational analysis methods for bladder cancer surveillance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019012260A true MX2019012260A (es) | 2020-01-27 |
Family
ID=62528860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019012260A MX2019012260A (es) | 2017-05-18 | 2018-05-17 | Metodos de analisis mutacional y de metilacion del adn para vigilancia del cancer de vejiga. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11649506B2 (es) |
| EP (1) | EP3625369B1 (es) |
| JP (1) | JP2020519296A (es) |
| CN (1) | CN110621788B (es) |
| AU (1) | AU2018269030A1 (es) |
| BR (1) | BR112019022360A2 (es) |
| ES (1) | ES2973607T3 (es) |
| IL (1) | IL269707A (es) |
| MX (1) | MX2019012260A (es) |
| SG (2) | SG10201912359XA (es) |
| WO (1) | WO2018213550A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201912359XA (en) * | 2017-05-18 | 2020-02-27 | Genomic Health Inc | Dna methylation and mutational analysis methods for bladder cancer surveillance |
| KR102164432B1 (ko) * | 2019-09-18 | 2020-10-13 | 한국과학기술원 | Dna 메틸화 변이를 이용한 면역항암치료 반응성 예측방법 |
| AU2021238717A1 (en) * | 2020-03-20 | 2022-08-25 | Singlera Health Technologies (Shanghai) Ltd. | Methods and kits for screening colorectal neoplasm |
| CN114634982A (zh) * | 2020-12-15 | 2022-06-17 | 广州市基准医疗有限责任公司 | 一种检测多核苷酸变异的方法 |
| CN113621691A (zh) * | 2021-09-27 | 2021-11-09 | 广东省妇幼保健院 | 基于一代测序技术直接检测KLF1基因启动子区CpG甲基化的方法和试剂盒 |
| CN116013528B (zh) * | 2023-01-10 | 2023-11-24 | 中山大学孙逸仙纪念医院 | 结合fish检测的膀胱癌术后复发风险预测方法、装置及介质 |
| CN116987787B (zh) * | 2023-06-09 | 2024-07-30 | 北京泛生子基因科技有限公司 | 检测膀胱癌是否复发的装置和计算机可读存储介质 |
| TWI886817B (zh) * | 2023-06-09 | 2025-06-11 | 臺北醫學大學 | 甲基化生物標記用於篩檢泌尿道上皮癌的方法 |
| CN117604101B (zh) * | 2023-09-11 | 2025-02-25 | 北京橡鑫生物科技有限公司 | 一种基因标志物组合、试剂盒及检测方法 |
| CN118006781B (zh) * | 2024-02-27 | 2025-01-07 | 广州中鑫基因医学科技有限公司 | 用于检测尿路上皮癌的标志物、引物组、高敏感性和高特异性的试剂盒及检测方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE534465T1 (de) | 2005-06-23 | 2011-12-15 | Biocartis Sa | Kartusche, system und verfahren für automatisierte medizinische diagnosen |
| ES2721424T3 (es) * | 2009-04-20 | 2019-07-31 | Univ Erasmus Med Ct Rotterdam | Método de diagnóstico del cáncer de vejiga |
| ES2669439T3 (es) | 2009-06-26 | 2018-05-25 | Epigenomics Ag | Métodos y ácidos nucleicos para el análisis del carcinoma de vejiga |
| CN103417983A (zh) * | 2012-05-18 | 2013-12-04 | 北京大学 | 新的凋亡相关分子tmem106a及其用途 |
| WO2014085666A1 (en) * | 2012-11-27 | 2014-06-05 | Board Of Regents, The University Of Texas System | Methods of characterizing and treating molecular subset of muscle-invasive bladder cancer |
| CN105705653A (zh) * | 2013-05-10 | 2016-06-22 | 南加州大学 | 针对膀胱癌的dna甲基化生物标志物 |
| US20160340740A1 (en) | 2014-01-30 | 2016-11-24 | The Regents Of The University Of California | Methylation haplotyping for non-invasive diagnosis (monod) |
| GB201511152D0 (en) * | 2015-06-24 | 2015-08-05 | Ucl Business Plc | Method of diagnosing bladder cancer |
| SG10201912359XA (en) * | 2017-05-18 | 2020-02-27 | Genomic Health Inc | Dna methylation and mutational analysis methods for bladder cancer surveillance |
-
2018
- 2018-05-17 SG SG10201912359XA patent/SG10201912359XA/en unknown
- 2018-05-17 EP EP18729258.6A patent/EP3625369B1/en active Active
- 2018-05-17 AU AU2018269030A patent/AU2018269030A1/en not_active Abandoned
- 2018-05-17 US US16/612,926 patent/US11649506B2/en active Active
- 2018-05-17 BR BR112019022360A patent/BR112019022360A2/pt not_active IP Right Cessation
- 2018-05-17 JP JP2019562614A patent/JP2020519296A/ja not_active Withdrawn
- 2018-05-17 CN CN201880032698.1A patent/CN110621788B/zh active Active
- 2018-05-17 WO PCT/US2018/033146 patent/WO2018213550A1/en not_active Ceased
- 2018-05-17 SG SG11201909113V patent/SG11201909113VA/en unknown
- 2018-05-17 ES ES18729258T patent/ES2973607T3/es active Active
- 2018-05-17 MX MX2019012260A patent/MX2019012260A/es unknown
-
2019
- 2019-09-26 IL IL26970719A patent/IL269707A/en unknown
-
2023
- 2023-04-04 US US18/130,547 patent/US20230374604A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL269707A (en) | 2019-11-28 |
| AU2018269030A1 (en) | 2019-10-17 |
| CN110621788A (zh) | 2019-12-27 |
| EP3625369B1 (en) | 2024-02-14 |
| BR112019022360A2 (pt) | 2020-05-19 |
| SG11201909113VA (en) | 2019-10-30 |
| US11649506B2 (en) | 2023-05-16 |
| EP3625369A1 (en) | 2020-03-25 |
| ES2973607T3 (es) | 2024-06-20 |
| SG10201912359XA (en) | 2020-02-27 |
| JP2020519296A (ja) | 2020-07-02 |
| WO2018213550A1 (en) | 2018-11-22 |
| US20200165686A1 (en) | 2020-05-28 |
| CA3057440A1 (en) | 2018-11-22 |
| US20230374604A1 (en) | 2023-11-23 |
| CN110621788B (zh) | 2024-10-15 |
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