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MX2019012252A - Composiciones y metodos para inhibir la expresion del gen alas1. - Google Patents

Composiciones y metodos para inhibir la expresion del gen alas1.

Info

Publication number
MX2019012252A
MX2019012252A MX2019012252A MX2019012252A MX2019012252A MX 2019012252 A MX2019012252 A MX 2019012252A MX 2019012252 A MX2019012252 A MX 2019012252A MX 2019012252 A MX2019012252 A MX 2019012252A MX 2019012252 A MX2019012252 A MX 2019012252A
Authority
MX
Mexico
Prior art keywords
compositions
methods
inhibiting expression
alas1 gene
alas1
Prior art date
Application number
MX2019012252A
Other languages
English (en)
Other versions
MX385048B (es
Inventor
Fitzgerald Kevin
Bettencourt Brian
Querbes William
Yasuda Makiko
J Desnick Robert
Original Assignee
Alnylam Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48326393&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2019012252(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alnylam Pharmaceuticals Inc filed Critical Alnylam Pharmaceuticals Inc
Publication of MX2019012252A publication Critical patent/MX2019012252A/es
Publication of MX385048B publication Critical patent/MX385048B/es

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    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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Abstract

La invención se refiere a composiciones de ácido ribonucleico bicatenario (ARNbc) que tienen como diana el gen ALAS1 y a métodos para utilizar tales composiciones de ARNbc con el fin de alterar (p. ej., inhibir) la expresión de ALAS1.
MX2019012252A 2012-04-10 2013-04-10 Composiciones y metodos para inhibir la expresion del gen alas1. MX385048B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261622288P 2012-04-10 2012-04-10
US13/835,613 US9133461B2 (en) 2012-04-10 2013-03-15 Compositions and methods for inhibiting expression of the ALAS1 gene
PCT/US2013/036006 WO2013155204A2 (en) 2012-04-10 2013-04-10 Compositions and methods for inhibiting expression of the alas1 gene

Publications (2)

Publication Number Publication Date
MX2019012252A true MX2019012252A (es) 2020-01-23
MX385048B MX385048B (es) 2025-03-14

Family

ID=48326393

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2014012215A MX368723B (es) 2012-04-10 2013-04-10 Composiciones y metodos para inhibir la expresion del gen alas1.
MX2019012252A MX385048B (es) 2012-04-10 2013-04-10 Composiciones y metodos para inhibir la expresion del gen alas1.
MX2021009118A MX2021009118A (es) 2012-04-10 2014-10-09 Composiciones y metodos para inhibir la expresion del gen alas1.

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MX2014012215A MX368723B (es) 2012-04-10 2013-04-10 Composiciones y metodos para inhibir la expresion del gen alas1.

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Application Number Title Priority Date Filing Date
MX2021009118A MX2021009118A (es) 2012-04-10 2014-10-09 Composiciones y metodos para inhibir la expresion del gen alas1.

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