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MX2019011119A - Metodos espectroscopicos para detectar y caracterizar microorganismos. - Google Patents

Metodos espectroscopicos para detectar y caracterizar microorganismos.

Info

Publication number
MX2019011119A
MX2019011119A MX2019011119A MX2019011119A MX2019011119A MX 2019011119 A MX2019011119 A MX 2019011119A MX 2019011119 A MX2019011119 A MX 2019011119A MX 2019011119 A MX2019011119 A MX 2019011119A MX 2019011119 A MX2019011119 A MX 2019011119A
Authority
MX
Mexico
Prior art keywords
intensity
irradiation intensity
change
rate
detect
Prior art date
Application number
MX2019011119A
Other languages
English (en)
Inventor
Verma Ravi
Yu Changjun
Original Assignee
Spectral Platforms Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spectral Platforms Inc filed Critical Spectral Platforms Inc
Publication of MX2019011119A publication Critical patent/MX2019011119A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/14—Streptococcus; Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06113—Coherent sources; lasers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Se proporcionan métodos y sistemas para la espectroscopia Raman resonante. Los métodos de acuerdo con ciertas modalidades incluyen la irradiación de una muestra con una fuente de luz monocromática a una primera intensidad de irradiación y una segunda intensidad de irradiación, determinar la intensidad de una o más dispersiones Raman resonante y dispersión de fluorescencia en la primera intensidad de irradiación y la segunda intensidad de irradiación, calcular una tasa de cambio de uno o más de la intensidad de la dispersión Raman resonante y fluorescencia en respuesta al cambio en la intensidad de irradiación desde la primera intensidad de irradiación a la segunda intensidad de irradiación y comparar uno o más de la tasa de cambio en la intensidad de la dispersión Raman resonante y la tasa de cambio en la intensidad de la dispersión de fluorescencia con la tasa de cambio en la intensidad de irradiación por la fuente de luz monocromática para determinar la respuesta Raman resonante de la muestra. Los métodos también incluyen determinar la presencia o ausencia de un microorganismo en una muestra y corregir las variaciones asociadas con la instrumentación de medición (por ejemplo, fuente de luz monocromática) y las variaciones asociadas con la muestra (por ejemplo, fluorescencia de compuestos no objetivo). También se proporcionan métodos para determinar la susceptibilidad antimicrobiana de un microorganismo a un agente antimicrobiano, así como métodos para caracterizar un fenotipo de un microorganismo desconocido en una muestra. También se proporcionan sistemas para practicar los métodos de la materia.
MX2019011119A 2017-03-20 2018-03-19 Metodos espectroscopicos para detectar y caracterizar microorganismos. MX2019011119A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762473876P 2017-03-20 2017-03-20
US201862614216P 2018-01-05 2018-01-05
PCT/US2018/023182 WO2018175346A1 (en) 2017-03-20 2018-03-19 Spectroscopic methods to detect and characterize microorganisms

Publications (1)

Publication Number Publication Date
MX2019011119A true MX2019011119A (es) 2019-12-19

Family

ID=63585732

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019011119A MX2019011119A (es) 2017-03-20 2018-03-19 Metodos espectroscopicos para detectar y caracterizar microorganismos.

Country Status (5)

Country Link
US (2) US11105747B2 (es)
EP (1) EP3602065A4 (es)
JP (1) JP7134995B2 (es)
MX (1) MX2019011119A (es)
WO (1) WO2018175346A1 (es)

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Also Published As

Publication number Publication date
US11105747B2 (en) 2021-08-31
JP2020519849A (ja) 2020-07-02
EP3602065A4 (en) 2020-12-23
EP3602065A1 (en) 2020-02-05
JP7134995B2 (ja) 2022-09-12
US20220113256A1 (en) 2022-04-14
US20180292324A1 (en) 2018-10-11
WO2018175346A1 (en) 2018-09-27

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