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MX2019006844A - Gliceril 3-hidroxibutiratos para el control de los síntomas de la migraña. - Google Patents

Gliceril 3-hidroxibutiratos para el control de los síntomas de la migraña.

Info

Publication number
MX2019006844A
MX2019006844A MX2019006844A MX2019006844A MX2019006844A MX 2019006844 A MX2019006844 A MX 2019006844A MX 2019006844 A MX2019006844 A MX 2019006844A MX 2019006844 A MX2019006844 A MX 2019006844A MX 2019006844 A MX2019006844 A MX 2019006844A
Authority
MX
Mexico
Prior art keywords
control
migraine
symptoms
hydroxybutyrates
glyceryl
Prior art date
Application number
MX2019006844A
Other languages
English (en)
Other versions
MX389468B (es
Inventor
Hashim Sami
Original Assignee
Neuroenergy Ventures Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuroenergy Ventures Inc filed Critical Neuroenergy Ventures Inc
Publication of MX2019006844A publication Critical patent/MX2019006844A/es
Publication of MX389468B publication Critical patent/MX389468B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225Polycarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se describe un método de control de la reducción y/o la profilaxis y/o el control de los síntomas de migraña mediante el uso de glicéridos de 3-hidroxibutato.
MX2019006844A 2016-12-23 2017-11-30 Gliceril 3-hidroxibutiratos para el control de los síntomas de la migraña MX389468B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/389,828 US20180177753A1 (en) 2016-12-23 2016-12-23 Glyceryl 3-hydroxybutyrates for migraine symptom management
PCT/US2017/063832 WO2018118369A1 (en) 2016-12-23 2017-11-30 Glyceryl 3-hydroxybutyrates for migraine symptom management

Publications (2)

Publication Number Publication Date
MX2019006844A true MX2019006844A (es) 2019-08-16
MX389468B MX389468B (es) 2025-03-20

Family

ID=62624821

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019006844A MX389468B (es) 2016-12-23 2017-11-30 Gliceril 3-hidroxibutiratos para el control de los síntomas de la migraña

Country Status (13)

Country Link
US (2) US20180177753A1 (es)
EP (1) EP3558458B1 (es)
JP (1) JP7108320B2 (es)
KR (1) KR102390608B1 (es)
CN (1) CN110167637B (es)
BR (1) BR112019012431A2 (es)
CA (1) CA3046350C (es)
ES (1) ES2962879T3 (es)
IL (1) IL267540B (es)
MX (1) MX389468B (es)
MY (1) MY190308A (es)
PT (1) PT3558458T (es)
WO (1) WO2018118369A1 (es)

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US12496283B2 (en) 2016-04-19 2025-12-16 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate and related compounds in humans
US12329734B2 (en) 2017-12-19 2025-06-17 Axcess Global Sciences, Llc Use of S-beta-hydroxybutyrate compounds for induction and maintenance of flow
US12521378B2 (en) 2016-04-19 2026-01-13 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate salt blend and related compounds in humans
US11944598B2 (en) 2017-12-19 2024-04-02 Axcess Global Sciences, Llc Compositions containing s-beta-hydroxybutyrate or non-racemic mixtures enriched with the s-enatiomer
US11202769B2 (en) 2017-11-22 2021-12-21 Axcess Global Sciences, Llc Ketone body esters of s-beta-hydroxybutyrate and/or s-1,3-butanediol for modifying metabolic function
US11806324B2 (en) 2018-04-18 2023-11-07 Axcess Global Sciences, Llc Beta-hydroxybutyric acid compositions and methods for oral delivery of ketone bodies
US12109182B2 (en) 2016-04-19 2024-10-08 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate and related compounds in humans
US10925843B2 (en) 2018-04-18 2021-02-23 Axcess Global Sciences, Llc Compositions and methods for keto stacking with beta-hydroxybutyrate and acetoacetate
US20230346721A1 (en) 2018-04-18 2023-11-02 Axcess Global Sciences, Llc Beta-hydroxybutyric acid compositions and methods for delivery of ketone bodies
US12533346B2 (en) 2016-04-19 2026-01-27 Axcess Global Sciences, Llc Administration of berberine metabolites
FI3558280T3 (fi) 2016-12-21 2023-07-13 Univ Kinderspital Beider Basel Migreenin ennaltaehkäisy ja hoito
US10376528B2 (en) 2017-03-10 2019-08-13 Tecton Group, Llc Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor
GB201715654D0 (en) 2017-09-27 2017-11-08 Tdeltas Ltd Method of treatment
US12090129B2 (en) 2017-11-22 2024-09-17 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
EP3880641B1 (de) * 2019-01-17 2023-03-15 KetoLipix Therapeutics GmbH Verfahren zur herstellung von glyceriden von hydroxycarbonsäuren
ES2965646T3 (es) * 2019-01-17 2024-04-16 Ketolipix Therapeutics Gmbh Procedimiento para la producción de lípidos que contienen unidades estructurales a base de glicéridos de ácidos hidroxicarboxílicos
IL278422B (en) * 2019-03-14 2022-09-01 Neuroenergy Ventures Inc A flavor masking formulation for ketone body compounds
US12472200B2 (en) 2019-05-15 2025-11-18 Axcess Global Sciences, Llc Autobiotic compositions and method for promoting healthy gut microbiome
US12239624B2 (en) 2019-05-30 2025-03-04 Neuroenergy Ventures, Inc. Glyceryl tris (beta-hydroxybutyrate) and neuronal transient ischemic attacks
EP3956283A1 (de) * 2019-06-12 2022-02-23 IOI Oleo GmbH Verfahren zur herstellung von polyolbasierten estern von acylverkappten 3-hydroxycarbonsäuren
US12167993B2 (en) 2019-06-21 2024-12-17 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
US11969430B1 (en) 2023-03-10 2024-04-30 Axcess Global Sciences, Llc Compositions containing paraxanthine and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance
US11950616B2 (en) 2019-06-21 2024-04-09 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
IT201900018488A1 (it) * 2019-10-10 2021-04-10 Dr Schaer S P A Procedimento di preparazione del tris-(3-idrossibutirrato)-gliceril estere
IT201900018491A1 (it) * 2019-10-10 2021-04-10 Dr Schaer S P A Procedimento di purificazione del tris-(3-idrossibutirrato)-gliceril estere
US12186297B2 (en) 2020-08-26 2025-01-07 Axcess Global Sciences, Llc Compositions and methods for increasing lean-to-fat mass ratio
AU2022387742A1 (en) 2021-11-12 2024-06-27 Arxada Ag Polyol-derived compounds
US20250002446A1 (en) * 2021-11-26 2025-01-02 Arxada Ag Acetoacetate Based Ketals
US20240299548A1 (en) * 2022-01-18 2024-09-12 Today, Inc. Molecules, formulations, and methods for nutritional support of athletes, patients, and others
US12023382B2 (en) 2022-01-18 2024-07-02 Today Inc. Molecules, formulations, and methods for nutritional support of athletes, patients, and others
WO2024083889A1 (en) 2022-10-18 2024-04-25 Arxada Ag Polyol-derived compounds
WO2025074001A2 (en) 2023-10-05 2025-04-10 Arxada Ag Enzymatic reduction of acetoacetate
WO2025196156A1 (en) 2024-03-20 2025-09-25 Arxada Ag Continuous hydrogenation process of acetoacetate esters
WO2025224319A1 (en) 2024-04-25 2025-10-30 Arxada Ag Reduction of acetoacetate esters in the presence of amines

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FI3558280T3 (fi) 2016-12-21 2023-07-13 Univ Kinderspital Beider Basel Migreenin ennaltaehkäisy ja hoito

Also Published As

Publication number Publication date
CN110167637B (zh) 2023-03-14
KR102390608B1 (ko) 2022-04-25
EP3558458A4 (en) 2020-08-12
BR112019012431A2 (pt) 2020-04-14
WO2018118369A1 (en) 2018-06-28
JP7108320B2 (ja) 2022-07-28
CN110167637A (zh) 2019-08-23
US10792269B2 (en) 2020-10-06
CA3046350C (en) 2022-08-16
IL267540A (en) 2019-08-29
ES2962879T3 (es) 2024-03-21
IL267540B (en) 2022-07-01
MX389468B (es) 2025-03-20
MY190308A (en) 2022-04-13
EP3558458A1 (en) 2019-10-30
US20180177753A1 (en) 2018-06-28
KR20190099465A (ko) 2019-08-27
PT3558458T (pt) 2023-11-27
US20190117612A1 (en) 2019-04-25
JP2020502250A (ja) 2020-01-23
CA3046350A1 (en) 2018-06-28
EP3558458B1 (en) 2023-10-18

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