MX2019006685A - Combinacion terapeutica para el tratamiento de cancer. - Google Patents
Combinacion terapeutica para el tratamiento de cancer.Info
- Publication number
- MX2019006685A MX2019006685A MX2019006685A MX2019006685A MX2019006685A MX 2019006685 A MX2019006685 A MX 2019006685A MX 2019006685 A MX2019006685 A MX 2019006685A MX 2019006685 A MX2019006685 A MX 2019006685A MX 2019006685 A MX2019006685 A MX 2019006685A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- treatment
- therapeutic combination
- combinations
- nerium
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title 1
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 2
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 206010009944 Colon cancer Diseases 0.000 abstract 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 abstract 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 abstract 1
- 241000893864 Nerium Species 0.000 abstract 1
- 244000187664 Nerium oleander Species 0.000 abstract 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 abstract 1
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 abstract 1
- 229960004316 cisplatin Drugs 0.000 abstract 1
- 201000005202 lung cancer Diseases 0.000 abstract 1
- 208000020816 lung neoplasm Diseases 0.000 abstract 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 abstract 1
- 201000001441 melanoma Diseases 0.000 abstract 1
- 201000002528 pancreatic cancer Diseases 0.000 abstract 1
- 208000008443 pancreatic carcinoma Diseases 0.000 abstract 1
- 229910052697 platinum Inorganic materials 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Esta invención se relaciona a combinaciones terapéuticas que comprenden un agente antineoplástico a base de platino, como cisplatino y un extracto de especies del género Nerium oleander, así como también métodos de uso de las combinaciones para tratar sujetos, incluyendo humanos, que sufren de ciertos cánceres, como cáncer de próstata, melanoma, cáncer pancreático, cáncer pulmonar, cáncer de mama o cáncer colorrectal.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161549386P | 2011-10-20 | 2011-10-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019006685A true MX2019006685A (es) | 2019-08-21 |
Family
ID=48141445
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014004527A MX365635B (es) | 2011-10-20 | 2012-10-20 | Combinacion terapeutica para el tratamiento de cancer. |
| MX2019006685A MX2019006685A (es) | 2011-10-20 | 2014-04-14 | Combinacion terapeutica para el tratamiento de cancer. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014004527A MX365635B (es) | 2011-10-20 | 2012-10-20 | Combinacion terapeutica para el tratamiento de cancer. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20130209579A1 (es) |
| EP (2) | EP3711754A1 (es) |
| JP (1) | JP6255346B2 (es) |
| CN (2) | CN110269940A (es) |
| AU (3) | AU2012325819B2 (es) |
| BR (1) | BR112014009421A2 (es) |
| CA (1) | CA2852274C (es) |
| GT (1) | GT201400071A (es) |
| IL (2) | IL231987B (es) |
| IN (1) | IN2014KN00796A (es) |
| MX (2) | MX365635B (es) |
| RU (2) | RU2014120179A (es) |
| WO (1) | WO2013059753A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101717301B1 (ko) * | 2008-10-14 | 2017-03-16 | 네리엄 바이오테크놀로지, 인크. | 강심 배당체의 추출방법 및 조성물 |
| CN116602954A (zh) * | 2015-04-22 | 2023-08-18 | 新纳特产品公司 | 共晶组合物及其药物用途 |
| CN108135920A (zh) * | 2015-10-05 | 2018-06-08 | 努卡那有限公司 | 组合疗法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1299100C (en) | 1986-05-13 | 1992-04-21 | Huseyin Ziya Ozel | Extracts of nerium species, methods of preparation and use therefor |
| JP2002526452A (ja) | 1998-09-24 | 2002-08-20 | オゼル・ファーマスーティカルズ・インコーポレイテッド | キョウチクトウ抽出物、その医薬組成物及びその調整方法 |
| US7407675B2 (en) * | 2002-12-27 | 2008-08-05 | The Trustees Of Columbia University In The City Of New York | Anti-neoplastic compositions comprising extracts of black cohosh |
| US20060205679A1 (en) * | 2004-10-22 | 2006-09-14 | Azaya Therapeutics, Inc. | Topical and oral formulations of cardiac glycosides for treating skin diseases |
| US7402325B2 (en) | 2005-07-28 | 2008-07-22 | Phoenix Biotechnology, Inc. | Supercritical carbon dioxide extract of pharmacologically active components from Nerium oleander |
| EP1803461A1 (en) * | 2005-12-27 | 2007-07-04 | Heinz-Herbert Fiebig | Therapeutic use of an extract from the leaves of Nerium oleander |
| PL2173337T3 (pl) | 2007-08-06 | 2014-11-28 | Univ Ohio | Fosfaplatyny i ich zastosowanie w leczeniu raków opornych na cisplatynę i karboplatynę |
| KR101717301B1 (ko) * | 2008-10-14 | 2017-03-16 | 네리엄 바이오테크놀로지, 인크. | 강심 배당체의 추출방법 및 조성물 |
-
2012
- 2012-10-20 MX MX2014004527A patent/MX365635B/es active IP Right Grant
- 2012-10-20 WO PCT/US2012/061226 patent/WO2013059753A1/en not_active Ceased
- 2012-10-20 EP EP20159407.4A patent/EP3711754A1/en not_active Withdrawn
- 2012-10-20 BR BR112014009421A patent/BR112014009421A2/pt not_active Application Discontinuation
- 2012-10-20 EP EP12841023.0A patent/EP2768498B1/en active Active
- 2012-10-20 CN CN201910226194.XA patent/CN110269940A/zh active Pending
- 2012-10-20 AU AU2012325819A patent/AU2012325819B2/en not_active Ceased
- 2012-10-20 CN CN201280051254.5A patent/CN104093405A/zh active Pending
- 2012-10-20 CA CA2852274A patent/CA2852274C/en not_active Expired - Fee Related
- 2012-10-20 RU RU2014120179/15A patent/RU2014120179A/ru unknown
- 2012-10-20 RU RU2017136415A patent/RU2017136415A/ru not_active Application Discontinuation
- 2012-10-20 JP JP2014537346A patent/JP6255346B2/ja not_active Expired - Fee Related
- 2012-10-20 IN IN796KON2014 patent/IN2014KN00796A/en unknown
-
2013
- 2013-03-15 US US13/838,739 patent/US20130209579A1/en not_active Abandoned
-
2014
- 2014-04-07 IL IL231987A patent/IL231987B/en not_active IP Right Cessation
- 2014-04-14 MX MX2019006685A patent/MX2019006685A/es unknown
- 2014-04-15 GT GT201400071A patent/GT201400071A/es unknown
-
2017
- 2017-10-31 AU AU2017254875A patent/AU2017254875A1/en not_active Abandoned
-
2019
- 2019-05-21 AU AU2019203577A patent/AU2019203577A1/en not_active Abandoned
- 2019-05-22 US US16/419,226 patent/US20190343908A1/en not_active Abandoned
-
2020
- 2020-06-24 IL IL275636A patent/IL275636A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN110269940A (zh) | 2019-09-24 |
| US20130209579A1 (en) | 2013-08-15 |
| GT201400071A (es) | 2015-09-17 |
| AU2012325819B2 (en) | 2017-08-03 |
| RU2014120179A (ru) | 2015-11-27 |
| CA2852274C (en) | 2019-08-06 |
| EP2768498A4 (en) | 2015-06-17 |
| AU2012325819A1 (en) | 2014-04-24 |
| EP2768498A1 (en) | 2014-08-27 |
| CN104093405A (zh) | 2014-10-08 |
| IL275636A (en) | 2020-08-31 |
| US20190343908A1 (en) | 2019-11-14 |
| IL231987B (en) | 2020-07-30 |
| IN2014KN00796A (es) | 2015-10-02 |
| WO2013059753A1 (en) | 2013-04-25 |
| RU2017136415A (ru) | 2019-02-08 |
| RU2017136415A3 (es) | 2021-02-08 |
| CA2852274A1 (en) | 2013-04-25 |
| JP2014530878A (ja) | 2014-11-20 |
| MX365635B (es) | 2019-06-10 |
| BR112014009421A2 (pt) | 2017-04-18 |
| IL231987A0 (en) | 2014-05-28 |
| AU2017254875A1 (en) | 2017-11-23 |
| AU2019203577A1 (en) | 2019-06-13 |
| EP2768498B1 (en) | 2020-03-04 |
| NZ623550A (en) | 2016-06-24 |
| MX2014004527A (es) | 2014-09-15 |
| JP6255346B2 (ja) | 2017-12-27 |
| EP3711754A1 (en) | 2020-09-23 |
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