[go: up one dir, main page]

MX2019006090A - Metodos para mejorar la respuesta inmune con everolimus, dactolisib o ambos. - Google Patents

Metodos para mejorar la respuesta inmune con everolimus, dactolisib o ambos.

Info

Publication number
MX2019006090A
MX2019006090A MX2019006090A MX2019006090A MX2019006090A MX 2019006090 A MX2019006090 A MX 2019006090A MX 2019006090 A MX2019006090 A MX 2019006090A MX 2019006090 A MX2019006090 A MX 2019006090A MX 2019006090 A MX2019006090 A MX 2019006090A
Authority
MX
Mexico
Prior art keywords
immune response
dactolisib
everolimus
methods
enhancing immune
Prior art date
Application number
MX2019006090A
Other languages
English (en)
Inventor
Mannick Joan
Morris Melody
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2019006090A publication Critical patent/MX2019006090A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere a un método para mejorar la respuesta inmune en un sujeto.
MX2019006090A 2016-11-23 2017-11-22 Metodos para mejorar la respuesta inmune con everolimus, dactolisib o ambos. MX2019006090A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662425766P 2016-11-23 2016-11-23
US201762476160P 2017-03-24 2017-03-24
US201762576511P 2017-10-24 2017-10-24
PCT/IB2017/001579 WO2018096402A1 (en) 2016-11-23 2017-11-22 Methods of enhancing immune response with everolimus, dactolisib or both

Publications (1)

Publication Number Publication Date
MX2019006090A true MX2019006090A (es) 2019-08-21

Family

ID=60957348

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019006090A MX2019006090A (es) 2016-11-23 2017-11-22 Metodos para mejorar la respuesta inmune con everolimus, dactolisib o ambos.

Country Status (12)

Country Link
US (3) US10441584B2 (es)
EP (1) EP3544608A1 (es)
JP (1) JP2020500930A (es)
KR (1) KR20190089005A (es)
CN (1) CN110114070A (es)
AU (1) AU2017363970A1 (es)
BR (1) BR112019010470A2 (es)
CA (1) CA3044355A1 (es)
IL (1) IL266750A (es)
MX (1) MX2019006090A (es)
TW (1) TW201825090A (es)
WO (1) WO2018096402A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11083725B2 (en) 2014-10-24 2021-08-10 St. Jude Children's Research Hospital Coordinated metabolic reprogramming in response to productive viral infections
JP2020500930A (ja) 2016-11-23 2020-01-16 ノバルティス アーゲー エベロリムス、ダクトリシブまたは両方で免疫応答を増強する方法
US10596165B2 (en) 2018-02-12 2020-03-24 resTORbio, Inc. Combination therapies
WO2020223154A1 (en) * 2019-05-01 2020-11-05 resTORbio, Inc. Methods of enhancing immune response

Family Cites Families (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1028606A (en) 1912-06-04 Victor Talking Machine Co Sound-box for talking-machines.
US1000480A (en) 1909-05-19 1911-08-15 J G Brill Co Car-truck.
US1044158A (en) 1911-01-27 1912-11-12 Allen H Fetzer Trolley-wheel.
ZA737247B (en) 1972-09-29 1975-04-30 Ayerst Mckenna & Harrison Rapamycin and process of preparation
US5681585A (en) 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5472712A (en) 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
GB9221220D0 (en) 1992-10-09 1992-11-25 Sandoz Ag Organic componds
WO1995014023A1 (en) 1993-11-19 1995-05-26 Abbott Laboratories Semisynthetic analogs of rapamycin (macrolides) being immunomodulators
PT734389E (pt) 1993-12-17 2000-09-29 Novartis Ag Derivados de rapamicina uteis como imunossupressores
US5362718A (en) 1994-04-18 1994-11-08 American Home Products Corporation Rapamycin hydroxyesters
US5741677A (en) 1995-06-07 1998-04-21 Geron Corporation Methods for measuring telomere length
AU712193B2 (en) 1995-06-09 1999-10-28 Novartis Ag Rapamycin derivatives
FR2736550B1 (fr) 1995-07-14 1998-07-24 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule
US6258823B1 (en) 1996-07-12 2001-07-10 Ariad Pharmaceuticals, Inc. Materials and method for treating or preventing pathogenic fungal infection
CA2230748C (en) 1997-03-14 2010-08-03 American Home Products Corporation Rapamycin formulations for oral administration
US6015815A (en) 1997-09-26 2000-01-18 Abbott Laboratories Tetrazole-containing rapamycin analogs with shortened half-lives
TW557297B (en) 1997-09-26 2003-10-11 Abbott Lab Rapamycin analogs having immunomodulatory activity, and pharmaceutical compositions containing same
ID27825A (id) 1998-03-26 2001-04-26 Fujisawa Pharmaceutical Co Sediaan lepas lambat
EP1212331B1 (en) 1999-08-24 2004-04-21 Ariad Gene Therapeutics, Inc. 28-epirapalogs
GB0008785D0 (en) 2000-04-10 2000-05-31 Novartis Ag Organic compounds
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
PL216224B1 (pl) 2002-02-01 2014-03-31 Ariad Pharmaceuticals Pochodne rapamycyny zawierające fosfor, kompozycja je zawierająca oraz ich zastosowanie
US20030203027A1 (en) 2002-04-26 2003-10-30 Ethicon, Inc. Coating technique for deposition of drug substance on a substrate
US7075204B2 (en) 2003-08-06 2006-07-11 Honeywell International, Inc. Threaded inner sleeve for generator magnet
AR045957A1 (es) 2003-10-03 2005-11-16 Novartis Ag Composicion farmaceutica y combinacion
US7220755B2 (en) 2003-11-12 2007-05-22 Biosensors International Group, Ltd. 42-O-alkoxyalkyl rapamycin derivatives and compositions comprising same
GB0419355D0 (en) 2004-08-31 2004-09-29 Novartis Ag Organic compounds
US8758816B2 (en) 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
GB2438544A (en) 2005-02-09 2007-11-28 Cooper Internat Corp Liquid formulations for treatment of diseases or conditions
MX2007010860A (es) 2005-03-08 2007-11-12 Lifecycle Pharma As Composiciones farmaceuticas que comprenden sirulimus y/o un analogo del mismo.
GB0510390D0 (en) 2005-05-20 2005-06-29 Novartis Ag Organic compounds
AU2007230964B2 (en) 2006-03-23 2012-07-19 Santen Pharmaceutical Co., Ltd. Formulations and methods for vascular permeability-related diseases or conditions
US20100266590A1 (en) 2006-08-02 2010-10-21 Demetri George D Combination therapy
EP1902708A1 (de) 2006-09-25 2008-03-26 Losan Pharma GmbH Wirkstoff enthaltende stabilisierte feste Arzneimittelformen und Verfahren zu ihrer Herstellung
KR20140091718A (ko) 2006-11-20 2014-07-22 노파르티스 아게 2-메틸-2-［4-(3-메틸-2-옥소-8-퀴놀린-3-일-2,3-디히드로-이미다조［4,5-ｃ］퀴놀린-1-일)-페닐］-프로피오니트릴의 염 및 결정 형태
KR101472607B1 (ko) 2007-02-20 2014-12-15 노파르티스 아게 지질 키나제 및 ｍＴＯＲ의 이중 억제제로서의 이미다조퀴놀린
AU2008280105B2 (en) 2007-07-24 2011-10-20 Novartis Ag Use of imidazoquinolines for the treatment of EGFR dependent diseases or diseases that have acquired resistance to agents that target EGFR family members
US20090082387A1 (en) 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched nvp-bez234
US20090088373A1 (en) 2007-09-28 2009-04-02 Gallo Richard L Use of compositions to enhance innate immune response
KR20100126465A (ko) 2008-03-05 2010-12-01 파나세아 바이오테크 리미티드 미코페놀레이트를 포함하는 변형 방출 제약 조성물 및 그것의 방법
WO2009118324A1 (en) 2008-03-26 2009-10-01 Novartis Ag 5imidazoquinolines and pyrimidine derivatives as potent modulators of vegf-driven angiogenic processes
CA2733203A1 (en) 2008-08-05 2010-02-11 Emory University Use of mtor inhibitors to enhance t cell immune responses
ES2553421T3 (es) 2008-08-26 2015-12-09 City Of Hope Método y composiciones para el funcionamiento potenciado del efector antitumoral de células T
EP2349275B1 (en) 2008-10-31 2017-03-08 Novartis AG Combination of a phosphatidylinositol-3-kinase (pi3k) inhibitor and a mtor inhibitor.
ES2645692T3 (es) 2008-11-11 2017-12-07 The Board Of Regents,The University Of Texas System Microcápsulas de rapamicina y su uso para el tratamiento del cáncer
US9452227B2 (en) 2008-11-25 2016-09-27 Alderbio Holdings Llc Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments
US8323649B2 (en) 2008-11-25 2012-12-04 Alderbio Holdings Llc Antibodies to IL-6 and use thereof
WO2010083298A1 (en) 2009-01-14 2010-07-22 Health Research Inc. Methods and compositions containing mtor inhibitors for enhancing immune responses
US20100233733A1 (en) 2009-02-10 2010-09-16 Nodality, Inc., A Delaware Corporation Multiple mechanisms for modulation of the pi3 kinase pathway
CA2757979A1 (en) 2009-04-09 2010-10-14 Alkermes Pharma Ireland Limited Controlled-release clozapine compositions
WO2010118419A2 (en) 2009-04-10 2010-10-14 Haiyan Qi Novel anti-aging agents and methods to identify them
CN101862297B (zh) 2009-04-14 2012-07-25 上海医药工业研究院 一种非水溶性药物的缓释微丸、其缓释口腔崩解片及其制备方法
CA2760932A1 (en) 2009-05-04 2010-11-11 Thierry Nivaggioli Mtor pathway inhibitors for treating ocular disorders
US20110230476A1 (en) 2009-09-09 2011-09-22 Avila Therapeutics, Inc. Pi3 kinase inhibitors and uses thereof
CN102199152A (zh) 2010-03-25 2011-09-28 高大新 杂环咪唑类磷脂激酶抑制剂
WO2012006619A2 (en) 2010-07-09 2012-01-12 Northeastern University ANTIPARASITIC AGENTS BASED ON mTOR INHIBITORS
AR083267A1 (es) 2010-10-04 2013-02-13 Novartis Ag Combinaciones farmaceuticas
WO2012075253A2 (en) 2010-12-03 2012-06-07 Novartis Ag Pharmaceutical compositions
PH12013501201A1 (en) 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
US20140206678A1 (en) 2011-01-27 2014-07-24 Kadmon Corporation, Llc Inhibitors of mtor kinase as anti -viral agent
US9358236B2 (en) 2011-02-16 2016-06-07 Novartis Ag Combinations of therapeutic agents for use in the treatment of neurodegenerative diseases
CN102138903B (zh) 2011-03-17 2012-12-12 苏州特瑞药业有限公司 一种依维莫司固体口服药物组合物
CA2844507A1 (en) 2011-08-10 2013-02-14 Novartis Pharma Ag Jak pi3k/mtor combination therapy
CN103906515A (zh) 2011-09-30 2014-07-02 达娜-法勃肿瘤研究所公司 治疗黏液表皮样癌的方法
WO2013050419A1 (en) 2011-10-06 2013-04-11 Novartis Ag Pharmaceutical compositions comprising 40 - o - ( 2 - hydroxy) ethyl - rapamycin
EP2638896A1 (en) 2012-03-14 2013-09-18 Bioneer A/S Cationic liposomal drug delivery system for specific targeting of human cd14+ monocytes in whole blood
EP2836239A1 (en) 2012-04-11 2015-02-18 The United States of America, as Represented By the Secretary, Department of Health and Human Services Chimeric antigen receptors targeting b-cell maturation antigen
EP2858631A1 (en) 2012-06-06 2015-04-15 Novartis AG Combination of a 17 -alpha -hydroxylase (c17, 20 - lyase) inhibitor and a specific pi-3k inhibitor for treating a tumor disease
US10799473B2 (en) 2013-03-04 2020-10-13 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Methods of inhibiting IGF-1R activation or downtream signalling thereof to reduce radiation-induced cellular senescence
TW201503912A (zh) 2013-03-19 2015-02-01 Novartis Ag 包含癌莫事（ｅｖｅｒｏｌｉｍｕｓ）之醫藥組合物
DK3004337T3 (da) 2013-05-29 2017-11-13 Cellectis Fremgangsmåde til konstruktion af T-celler til immunoterapi ved brug af RNA-guidet Cas nuklease-system
KR101582264B1 (ko) 2013-06-27 2016-01-04 삼성전자 주식회사 유기 박막용 조성물, 유기 박막 및 상기 유기 박막을 포함하는 전자 소자
US9033062B2 (en) * 2013-07-11 2015-05-19 Caterpillar Inc. Control system for a machine
JP2016537345A (ja) 2013-11-13 2016-12-01 ノバルティス アーゲー 免疫応答を増強するためのｍＴＯＲ阻害剤
RU2719030C2 (ru) 2014-06-06 2020-04-16 Блубёрд Био, Инк. Улучшенные композиции на основе t-клеток
WO2016014530A1 (en) 2014-07-21 2016-01-28 Novartis Ag Combinations of low, immune enhancing. doses of mtor inhibitors and cars
SG10201913782UA (en) 2014-07-21 2020-03-30 Novartis Ag Treatment of cancer using a cll-1 chimeric antigen receptor
US9777061B2 (en) 2014-07-21 2017-10-03 Novartis Ag Treatment of cancer using a CD33 chimeric antigen receptor
US10174095B2 (en) 2014-07-21 2019-01-08 Novartis Ag Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor
US20170274014A1 (en) 2014-07-21 2017-09-28 Jennifer Brogdon Combinations of low, immune enhancing, doses of mtor inhibitors and cars
WO2016028896A1 (en) 2014-08-19 2016-02-25 Novartis Ag Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment
US11083725B2 (en) * 2014-10-24 2021-08-10 St. Jude Children's Research Hospital Coordinated metabolic reprogramming in response to productive viral infections
WO2016079332A1 (en) 2014-11-21 2016-05-26 Technical University Of Denmark Gel formulations for improving immunotherapy
MX2017014776A (es) 2015-05-20 2018-02-15 Novartis Ag Combinacion farmaceutica de everolimus con dactolisib.
JP2020500930A (ja) 2016-11-23 2020-01-16 ノバルティス アーゲー エベロリムス、ダクトリシブまたは両方で免疫応答を増強する方法

Also Published As

Publication number Publication date
WO2018096402A1 (en) 2018-05-31
US11045463B2 (en) 2021-06-29
BR112019010470A2 (pt) 2019-09-10
AU2017363970A1 (en) 2019-06-20
TW201825090A (zh) 2018-07-16
CN110114070A (zh) 2019-08-09
KR20190089005A (ko) 2019-07-29
EP3544608A1 (en) 2019-10-02
IL266750A (en) 2019-07-31
CA3044355A1 (en) 2018-05-31
US20200061051A1 (en) 2020-02-27
US20180161319A1 (en) 2018-06-14
JP2020500930A (ja) 2020-01-16
US20200054624A1 (en) 2020-02-20
US10993940B2 (en) 2021-05-04
US10441584B2 (en) 2019-10-15

Similar Documents

Publication Publication Date Title
PH12020550781A1 (en) Anti-jagged1 antibodies and methods of use
PH12018500711A1 (en) Anti-pd1 antibodies and methods of use
PH12016501763A1 (en) Multispecific antibodies
ZA201902141B (en) Acid-alpha glucosidase variants and uses thereof
PH12017500877A1 (en) ANTI-CD79b ANTIBODIES AND METHODS OF USE
PH12016501894B1 (en) Anti-ox40 antibodies and methods of use
MY193661A (en) Anti-tim3 antibodies and methods of use
TN2017000246A1 (en) Anti-c10orf54 antibodies and uses thereof
ZA201902140B (en) Acid-alpha glucosidase variants and uses thereof
MX2021010460A (es) Metodo de tratamiento con tradipitant.
MX2017011223A (es) Variantes de protoxina ii y metodos de uso.
MY190747A (en) Method for producing silazane-siloxane copolymers and the use of such copolymers
MX2017012654A (es) Variantes de protoxina-ii y metodos de uso.
MX2019006090A (es) Metodos para mejorar la respuesta inmune con everolimus, dactolisib o ambos.
MX382187B (es) Extracto concentrado de sabadilla.
HK40014245A (en) Methods of enhancing immune response with everolimus, dactolisib or both
EA201991165A1 (ru) Способы усиления иммунного ответа с помощью эверолимуса, дактолисиба или обоих
AU2014904843A0 (en) Method and system for people to locate and communicate with each other as part of an exclusive social club.
AU2014904728A0 (en) Method and system for people to locate and communicate with each other as part of an exclusive social club.
UA101750U (ru) Применение омега как органопротектора при токсическом гепатите
TH1501004582A (th) องค์ประกอบและวิธีการของการเพิ่มการตอบสนองทางภูมิคุ้มกันต่อไอมีเรีย(Eimeria) หรือการจำกัดการติดเชื้อไอมีเรีย
AU2014904725A0 (en) Method and system for people to find and interact with each other as part of an exclusive social club.
UA90961U (uk) 3Н-ТІАЗОЛО[4,5-b]ХІНАКСОЛІН-2-ОН, ЩО ПРОЯВЛЯЄ АНТИЕКСУДАТИВНУ ДІЮ
NZ744340A (en) Anti-jagged1 antibodies and methods of use
AU363319S (en) Spacer bracket