MX2019005748A - Biomarcadores relacionados a la funcion renal y metodos para usar los mismos. - Google Patents
Biomarcadores relacionados a la funcion renal y metodos para usar los mismos.Info
- Publication number
- MX2019005748A MX2019005748A MX2019005748A MX2019005748A MX2019005748A MX 2019005748 A MX2019005748 A MX 2019005748A MX 2019005748 A MX2019005748 A MX 2019005748A MX 2019005748 A MX2019005748 A MX 2019005748A MX 2019005748 A MX2019005748 A MX 2019005748A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- biomarkers
- renal function
- kidney
- biomarkers related
- Prior art date
Links
- 239000000090 biomarker Substances 0.000 title abstract 4
- 230000003907 kidney function Effects 0.000 title abstract 4
- 208000020832 chronic kidney disease Diseases 0.000 abstract 2
- 208000009304 Acute Kidney Injury Diseases 0.000 abstract 1
- 208000033626 Renal failure acute Diseases 0.000 abstract 1
- 201000011040 acute kidney failure Diseases 0.000 abstract 1
- 150000003384 small molecules Chemical class 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/64—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving ketones
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/70—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving creatine or creatinine
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Se proporcionan biomarcadores de la función renal y métodos para usar los biomarcadores para evaluar la función renal, monitorear la función renal, diagnosticar lesiones renales agudas, y diagnosticar enfermedades renales crónicas. También se proporcionan modalidades de entidades de moléculas pequeñas como biomarcadores para enfermedades renales crónicas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361822965P | 2013-05-14 | 2013-05-14 | |
| PCT/US2014/037762 WO2014186311A1 (en) | 2013-05-14 | 2014-05-13 | Biomarkers related to kidney function and methods using the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019005748A true MX2019005748A (es) | 2019-08-12 |
| MX391220B MX391220B (es) | 2025-03-21 |
Family
ID=51898805
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019005748A MX391220B (es) | 2013-05-14 | 2014-05-13 | Biomarcadores relacionados a la funcion renal y metodos para usar los mismos. |
| MX2015015561A MX365061B (es) | 2013-05-14 | 2014-05-13 | Biomarcadores relacionados a la funcion renal y metodos para usar los mismos. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015015561A MX365061B (es) | 2013-05-14 | 2014-05-13 | Biomarcadores relacionados a la funcion renal y metodos para usar los mismos. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10539575B2 (es) |
| EP (3) | EP3546940B1 (es) |
| JP (1) | JP6595984B2 (es) |
| CN (2) | CN110196335A (es) |
| AU (1) | AU2014265669B2 (es) |
| BR (1) | BR112015028253A2 (es) |
| CA (2) | CA3184836A1 (es) |
| ES (2) | ES2871823T3 (es) |
| MX (2) | MX391220B (es) |
| WO (1) | WO2014186311A1 (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3546940B1 (en) * | 2013-05-14 | 2021-02-17 | Metabolon, Inc. | Biomarkers related to kidney function and methods using the same |
| JP6560200B2 (ja) | 2013-10-17 | 2019-08-14 | ザ ジェネラル ホスピタル コーポレイション | 自己免疫疾患の治療に応答性の対象を同定する方法およびそれを治療するための組成物 |
| EP3650852B1 (en) * | 2015-01-09 | 2021-08-18 | Global Genomics Group, LLC | Blood based biomarkers for diagnosing atherosclerotic coronary artery disease |
| WO2016115496A1 (en) * | 2015-01-15 | 2016-07-21 | Joslin Diabetes Center | Metabolite biomarkers predictive of renal disease in diabetic patients |
| WO2017059132A1 (en) * | 2015-09-29 | 2017-04-06 | The General Hospital Corporation | Methods of treating and diagnosing disease using biomarkers for bcg therapy |
| US20170234874A1 (en) * | 2015-10-07 | 2017-08-17 | Clearbridge Biophotonics Pte Ltd. | Integrated visual morphology and cell protein expression using resonance-light scattering |
| US12057228B1 (en) * | 2015-12-30 | 2024-08-06 | Cerner Innovation, Inc. | Predicting newly incident chronic kidney disease |
| WO2018022866A1 (en) | 2016-07-28 | 2018-02-01 | Metabolon, Inc. | Diagnostic methods, therapeutic agents and uses thereof |
| DK3552022T3 (da) * | 2016-11-25 | 2021-08-23 | Implexion AB | Metaboliske lidelser |
| US11619636B2 (en) | 2016-12-19 | 2023-04-04 | Metabolon, Inc. | Mass spectrometry assay method for detection and quantitation of kidney function metabolites |
| CN108956790A (zh) * | 2017-05-18 | 2018-12-07 | 中国人民解放军第二军医大学第二附属医院 | 一组氨基酸标志物在急性肾损伤诊断试剂盒中的应用 |
| CN107132266A (zh) * | 2017-06-21 | 2017-09-05 | 佛山科学技术学院 | 一种基于随机森林的水质分类方法及系统 |
| US11026625B2 (en) | 2017-08-08 | 2021-06-08 | Fresenius Medical Care Holdings, Inc. | Systems and methods for treating and estimating progression of chronic kidney disease |
| CN107326093B (zh) * | 2017-09-04 | 2020-01-21 | 东南大学 | 基于Taqman探针的慢性肾脏病相关基因检测荧光定量PCR一步法试剂盒及其应用 |
| WO2019067699A1 (en) * | 2017-09-28 | 2019-04-04 | Metabolon, Inc. | COMPOUNDS, REAGENTS AND USES THEREOF |
| ES2953127T3 (es) * | 2018-01-19 | 2023-11-08 | Mars Inc | Biomarcadores y algoritmos de clasificación para enfermedad renal crónica en gatos |
| EP3821254A1 (en) * | 2018-07-14 | 2021-05-19 | Mars Incorporated | Biomarkers and test models for chronic kidney disease |
| CN113454462A (zh) * | 2019-02-20 | 2021-09-28 | 株式会社合伙企业 | 固相反应芯片和使用该固相反应芯片的测定方法 |
| CN112305089B (zh) * | 2019-07-26 | 2022-04-29 | 长沙都正生物科技股份有限公司 | 一种慢性肾病诊断生物标记物及其应用 |
| EP4004541A1 (en) * | 2019-07-26 | 2022-06-01 | Fundació Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) | Ergothioneine, s-methyl-ergothioneine, and uses thereof |
| CN111487338B (zh) * | 2020-04-16 | 2022-06-10 | 中南大学湘雅二医院 | 一种与肾功能相关的无创生物标记物及其应用 |
| WO2021232211A1 (zh) * | 2020-05-19 | 2021-11-25 | 深圳市中医院 | 诊断肾病的标志物以及诊断方法 |
| CN114910587B (zh) * | 2022-05-12 | 2024-03-19 | 军科正源(上海)生物医药科技有限公司 | 一种尿液检测用高效液相-串联质谱分析方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02196787A (ja) * | 1989-01-25 | 1990-08-03 | Otsuka Pharmaceut Co Ltd | シュードウリジン誘導体 |
| JPH0661278B2 (ja) * | 1990-09-18 | 1994-08-17 | 旭化成工業株式会社 | ミオイノシトールの高感度定量法および定量用組成物 |
| US5712084A (en) * | 1995-09-08 | 1998-01-27 | Research Corporation Technologies, Inc. | Donor kidney viability test for improved preservation |
| CN101377492B (zh) | 2007-08-29 | 2014-04-23 | 北京九强生物技术股份有限公司 | 胱抑素c测定试剂盒 |
| JP5947544B2 (ja) * | 2008-08-29 | 2016-07-06 | アスチュート メディカル,インコーポレイテッド | 腎損傷および腎不全の診断および予後のための方法および組成物 |
| US9421330B2 (en) | 2008-11-03 | 2016-08-23 | Bayer Healthcare Llc | Mitigation of contrast-induced nephropathy |
| CN104034901A (zh) * | 2008-11-22 | 2014-09-10 | 阿斯图特医药公司 | 用于诊断和预后肾损伤和肾衰竭的方法和组合物 |
| WO2010124269A1 (en) * | 2009-04-24 | 2010-10-28 | National Center For Genome Resources | Methods for diagnosis of sepsis and risk of death |
| JP5197846B2 (ja) | 2009-04-30 | 2013-05-15 | 紀陽 田仲 | 腎疾患重篤度を判定する方法又は装置若しくはその作動方法 |
| CN102458418B (zh) * | 2009-06-08 | 2015-09-16 | 夸克制药公司 | 一种寡核苷酸化合物的制药用途 |
| US8709816B2 (en) | 2009-09-04 | 2014-04-29 | Tohoku University | Human renal disease marker substance |
| CN102725636B (zh) * | 2009-12-20 | 2015-04-01 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
| US8980548B2 (en) | 2010-05-19 | 2015-03-17 | Metabolon, Inc. | Methods and reagents for metabolomics and histology in a biological sample and a kit for the same |
| US9465039B2 (en) * | 2010-08-06 | 2016-10-11 | Mycartis Nv | Perlecan as a biomarker for renal dysfunction |
| JP5916058B2 (ja) * | 2011-08-26 | 2016-05-11 | 国立大学法人東北大学 | 細胞ストレス状態のバイオマーカー |
| KR20140074293A (ko) * | 2011-09-14 | 2014-06-17 | 바스프 에스이 | 신장 독성을 평가하기 위한 수단 및 방법 |
| WO2013048344A1 (en) * | 2011-09-29 | 2013-04-04 | National University Of Singapore | Urinary metabolomic markers for renal insufficiency |
| EP3546940B1 (en) * | 2013-05-14 | 2021-02-17 | Metabolon, Inc. | Biomarkers related to kidney function and methods using the same |
| WO2018022866A1 (en) * | 2016-07-28 | 2018-02-01 | Metabolon, Inc. | Diagnostic methods, therapeutic agents and uses thereof |
-
2014
- 2014-05-13 EP EP19176215.2A patent/EP3546940B1/en active Active
- 2014-05-13 US US14/889,930 patent/US10539575B2/en active Active
- 2014-05-13 WO PCT/US2014/037762 patent/WO2014186311A1/en not_active Ceased
- 2014-05-13 EP EP14797070.1A patent/EP2997366B1/en active Active
- 2014-05-13 AU AU2014265669A patent/AU2014265669B2/en active Active
- 2014-05-13 CN CN201910484069.9A patent/CN110196335A/zh active Pending
- 2014-05-13 ES ES19176215T patent/ES2871823T3/es active Active
- 2014-05-13 CN CN201480027332.7A patent/CN105209909B/zh active Active
- 2014-05-13 CA CA3184836A patent/CA3184836A1/en active Pending
- 2014-05-13 BR BR112015028253A patent/BR112015028253A2/pt not_active Application Discontinuation
- 2014-05-13 ES ES14797070T patent/ES2702123T3/es active Active
- 2014-05-13 CA CA2911204A patent/CA2911204C/en active Active
- 2014-05-13 JP JP2016514016A patent/JP6595984B2/ja active Active
- 2014-05-13 EP EP18183240.3A patent/EP3410115A1/en not_active Withdrawn
- 2014-05-13 MX MX2019005748A patent/MX391220B/es unknown
- 2014-05-13 MX MX2015015561A patent/MX365061B/es active IP Right Grant
-
2019
- 2019-12-02 US US16/700,098 patent/US20200103417A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX2015015561A (es) | 2016-02-05 |
| CN105209909B (zh) | 2019-06-07 |
| CA2911204C (en) | 2023-03-28 |
| CN110196335A (zh) | 2019-09-03 |
| AU2014265669B2 (en) | 2020-05-14 |
| HK1218331A1 (zh) | 2017-02-10 |
| EP2997366B1 (en) | 2018-10-10 |
| BR112015028253A2 (pt) | 2017-07-25 |
| CN105209909A (zh) | 2015-12-30 |
| EP2997366A1 (en) | 2016-03-23 |
| EP3546940B1 (en) | 2021-02-17 |
| EP2997366A4 (en) | 2017-04-12 |
| EP3546940A1 (en) | 2019-10-02 |
| JP2016520192A (ja) | 2016-07-11 |
| ES2871823T3 (es) | 2021-11-02 |
| EP3410115A1 (en) | 2018-12-05 |
| CA2911204A1 (en) | 2014-11-20 |
| US20200103417A1 (en) | 2020-04-02 |
| JP6595984B2 (ja) | 2019-10-23 |
| US10539575B2 (en) | 2020-01-21 |
| CA3184836A1 (en) | 2014-11-20 |
| ES2702123T3 (es) | 2019-02-27 |
| MX365061B (es) | 2019-05-22 |
| HK1222905A1 (en) | 2017-07-14 |
| AU2014265669A1 (en) | 2015-12-24 |
| WO2014186311A1 (en) | 2014-11-20 |
| US20160116486A1 (en) | 2016-04-28 |
| MX391220B (es) | 2025-03-21 |
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