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MX2018015022A - Métodos para el tratamiento de la enfermedad de alzheimer. - Google Patents

Métodos para el tratamiento de la enfermedad de alzheimer.

Info

Publication number
MX2018015022A
MX2018015022A MX2018015022A MX2018015022A MX2018015022A MX 2018015022 A MX2018015022 A MX 2018015022A MX 2018015022 A MX2018015022 A MX 2018015022A MX 2018015022 A MX2018015022 A MX 2018015022A MX 2018015022 A MX2018015022 A MX 2018015022A
Authority
MX
Mexico
Prior art keywords
disease
methods
treating alzheimer
subject
amyloid
Prior art date
Application number
MX2018015022A
Other languages
English (en)
Inventor
Joseph Sevigny Jeffrey
Lugene Williams Leslie
Phillip Boot Brendon
Original Assignee
Biogen Int Neuroscience Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Int Neuroscience Gmbh filed Critical Biogen Int Neuroscience Gmbh
Publication of MX2018015022A publication Critical patent/MX2018015022A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515—Complete light chain, i.e. VL + CL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se proporcionan métodos para tratar la enfermedad de Alzheimer en un sujeto humano que lo necesita cuando el sujeto desarrolla una anomalía en la imagen relacionada con el amiloide (ARIA) durante un régimen de tratamiento que comprende la administración de múltiples dosis de un anticuerpo antibeta-amiloide (por ejemplo, BIIB037) al sujeto.
MX2018015022A 2016-06-07 2017-06-06 Métodos para el tratamiento de la enfermedad de alzheimer. MX2018015022A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662346818P 2016-06-07 2016-06-07
US201662435531P 2016-12-16 2016-12-16
PCT/EP2017/063711 WO2017211827A1 (en) 2016-06-07 2017-06-06 Methods for treating alzheimer's disease

Publications (1)

Publication Number Publication Date
MX2018015022A true MX2018015022A (es) 2019-08-14

Family

ID=59067640

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018015022A MX2018015022A (es) 2016-06-07 2017-06-06 Métodos para el tratamiento de la enfermedad de alzheimer.

Country Status (12)

Country Link
US (2) US20200308259A1 (es)
EP (1) EP3464350A1 (es)
JP (3) JP2019517540A (es)
KR (2) KR20230165883A (es)
CN (3) CN109476730A (es)
AU (2) AU2017276656A1 (es)
BR (1) BR112018075300A2 (es)
CA (1) CA3026598A1 (es)
IL (1) IL263433B2 (es)
MA (1) MA45149A (es)
MX (1) MX2018015022A (es)
WO (1) WO2017211827A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201827467A (zh) 2016-11-03 2018-08-01 比利時商健生藥品公司 焦穀胺酸類澱粉蛋白－β之抗體及其用途
EP3696192A1 (en) 2019-02-15 2020-08-19 Consejo Superior De Investigaciones Científicas Therapeutic target and monoclonal antibodies against it for the diagnosis and treatment of alzheimer´s disease
WO2020193644A1 (en) 2019-03-26 2020-10-01 Janssen Pharmaceutica Nv ANTIBODIES TO PYROGLUTAMATE AMYLOID-ß AND USES THEREOF
CN110511276A (zh) * 2019-08-13 2019-11-29 王跃驹 植物作为宿主在表达Aducanumab抗体中的应用
US20220372123A1 (en) * 2019-10-22 2022-11-24 Biogen Ma Inc. Anti-beta-amyloid antibody for treating alzheimer's disease
US12435129B2 (en) 2020-07-23 2025-10-07 Othair Prothena Limited Anti-Aβ antibodies
KR102321601B1 (ko) * 2020-11-19 2021-11-05 주식회사 휴런 뇌 영상을 이용한 알츠하이머병의 생물학적 분류 장치 및 방법
TW202313111A (zh) * 2021-06-07 2023-04-01 美商百健Ｍａ公司 治療阿茲海默症之方法
WO2023055733A1 (en) * 2021-09-30 2023-04-06 The Scripps Research Institute Compounds for reducing neuroinflammation
AU2022389917A1 (en) * 2021-11-19 2024-05-23 Ap Biosciences, Inc. Bispecific antibodies targeting cd137 and uses thereof for anti-cancer immunotherapy

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY165105A (en) * 2006-07-14 2018-02-28 Ac Immune Sa Humanized antibody against amyloid beta
ES2635317T3 (es) * 2007-01-05 2017-10-03 University Of Zurich Anticuerpo anti-beta-amiloide y sus usos
MX345092B (es) 2010-10-11 2017-01-17 Univ Zuerich Anticuerpos anti-tau humanos,.
CA2888322A1 (en) * 2012-10-15 2014-04-24 Medimmune Limited Antibodies to amyloid beta
JP2016501247A (ja) * 2012-12-07 2016-01-18 バイオジェン インターナショナル ニューロサイエンス ゲーエムベーハー 抗Ａβ抗体を使用して脳アミロイド斑を減少させる方法
CN111205368B (zh) 2012-12-21 2023-05-09 比奥根Ma公司 人抗-tau抗体
KR20240094017A (ko) * 2014-02-08 2024-06-24 제넨테크, 인크. 알츠하이머 질환을 치료하는 방법
MA41115A (fr) * 2014-12-02 2017-10-10 Biogen Int Neuroscience Gmbh Procédé de traitement de la maladie d'alzheimer

Also Published As

Publication number Publication date
MA45149A (fr) 2019-04-10
BR112018075300A2 (pt) 2019-04-30
US20200308259A1 (en) 2020-10-01
KR20230165883A (ko) 2023-12-05
EP3464350A1 (en) 2019-04-10
IL263433B2 (en) 2024-03-01
IL263433B1 (en) 2023-11-01
JP2022145965A (ja) 2022-10-04
CN114796481A (zh) 2022-07-29
WO2017211827A1 (en) 2017-12-14
JP2019517540A (ja) 2019-06-24
CA3026598A1 (en) 2017-12-14
JP2025160337A (ja) 2025-10-22
IL263433A (en) 2019-01-31
CN114931635A (zh) 2022-08-23
US20220281963A1 (en) 2022-09-08
AU2024216442A1 (en) 2024-10-17
AU2017276656A1 (en) 2018-12-13
KR20190021311A (ko) 2019-03-05
CN109476730A (zh) 2019-03-15

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