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MX2018014915A - Tratamiento de enfermedades colestasicas intrahepaticas. - Google Patents

Tratamiento de enfermedades colestasicas intrahepaticas.

Info

Publication number
MX2018014915A
MX2018014915A MX2018014915A MX2018014915A MX2018014915A MX 2018014915 A MX2018014915 A MX 2018014915A MX 2018014915 A MX2018014915 A MX 2018014915A MX 2018014915 A MX2018014915 A MX 2018014915A MX 2018014915 A MX2018014915 A MX 2018014915A
Authority
MX
Mexico
Prior art keywords
treatment
intrahepatic cholestatic
cholestatic diseases
diseases
intrahepatic
Prior art date
Application number
MX2018014915A
Other languages
English (en)
Other versions
MX390417B (es
Inventor
A Mcwherter Charles
Boudes Pol
Original Assignee
Cymabay Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cymabay Therapeutics Inc filed Critical Cymabay Therapeutics Inc
Publication of MX2018014915A publication Critical patent/MX2018014915A/es
Publication of MX390417B publication Critical patent/MX390417B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Tratamiento de enfermedades colestásicas intrahepáticas mediante la terapia con seladelpar o una sal del mismo.
MX2018014915A 2016-05-31 2017-04-26 Tratamiento de enfermedades colestasicas intrahepaticas. MX390417B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662343688P 2016-05-31 2016-05-31
PCT/US2017/029620 WO2017209865A1 (en) 2016-05-31 2017-04-26 Treatment of intrahepatic cholestatic diseases

Publications (2)

Publication Number Publication Date
MX2018014915A true MX2018014915A (es) 2019-04-24
MX390417B MX390417B (es) 2025-03-20

Family

ID=58699276

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018014915A MX390417B (es) 2016-05-31 2017-04-26 Tratamiento de enfermedades colestasicas intrahepaticas.

Country Status (27)

Country Link
US (5) US10272058B2 (es)
EP (1) EP3463328B1 (es)
JP (1) JP7079735B2 (es)
KR (1) KR102408288B1 (es)
CN (1) CN109195594A (es)
AU (1) AU2017274293B2 (es)
BR (1) BR112018074147A2 (es)
CA (1) CA3024155C (es)
CY (1) CY1125465T1 (es)
DK (1) DK3463328T3 (es)
ES (1) ES2921230T3 (es)
HR (1) HRP20220903T1 (es)
HU (1) HUE059838T2 (es)
IL (1) IL263372B2 (es)
LT (1) LT3463328T (es)
MX (1) MX390417B (es)
NZ (1) NZ748721A (es)
PL (1) PL3463328T3 (es)
PT (1) PT3463328T (es)
RS (1) RS63345B1 (es)
RU (1) RU2765460C2 (es)
SG (1) SG11201810123SA (es)
SI (1) SI3463328T1 (es)
SM (1) SMT202200471T1 (es)
UA (1) UA122719C2 (es)
WO (1) WO2017209865A1 (es)
ZA (1) ZA201808360B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9486428B2 (en) 2014-03-20 2016-11-08 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
US10272058B2 (en) 2014-03-20 2019-04-30 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
US10512622B2 (en) 2017-07-14 2019-12-24 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
BR112021009038A2 (pt) * 2018-11-16 2021-08-10 Cymabay Therapeutics, Inc. tratamento combinado de nafld e nash
AU2022214948B2 (en) * 2021-02-01 2023-07-13 Cymabay Therapeutics, Inc. Treatment of cholangiopathies with seladelpar

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7101993B1 (en) 1990-01-11 2006-09-05 Isis Pharmaceuticals, Inc. Oligonucleotides containing 2′-O-modified purines
US7015315B1 (en) 1991-12-24 2006-03-21 Isis Pharmaceuticals, Inc. Gapped oligonucleotides
US5739135A (en) 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US6222025B1 (en) 1995-03-06 2001-04-24 Isis Pharmaceuticals, Inc. Process for the synthesis of 2′-O-substituted pyrimidines and oligomeric compounds therefrom
US6166197A (en) 1995-03-06 2000-12-26 Isis Pharmaceuticals, Inc. Oligomeric compounds having pyrimidine nucleotide (S) with 2'and 5 substitutions
CZ243498A3 (cs) 1996-02-14 1999-09-15 Isis Pharmaceuticals, Inc. Oligonukleotidy s mezerou a modifikovaným cukrem
US5883109A (en) 1996-07-24 1999-03-16 Bristol-Myers Squibb Company Method for lowering serum lipid levels employing an MTP inhibitor in combination with another cholesterol lowering drug
US6066653A (en) 1997-01-17 2000-05-23 Bristol-Myers Squibb Co. Method of treating acid lipase deficiency diseases with an MTP inhibitor and cholesterol lowering drugs
US7407943B2 (en) 2001-08-01 2008-08-05 Isis Pharmaceuticals, Inc. Antisense modulation of apolipoprotein B expression
US7511131B2 (en) 2002-11-13 2009-03-31 Genzyme Corporation Antisense modulation of apolipoprotein B expression
US7981915B2 (en) 2003-04-30 2011-07-19 Beth Israel Deaconess Medical Center Methods for modulating PPAR biological activity for the treatment of diseases caused by mutations in the CFTR gene
PT1667964E (pt) 2003-09-19 2009-09-02 Janssen Pharmaceutica Nv Ácidos 4-((fenoxialquil)tio)-fenoxiacéticos e análogos
JP5697296B2 (ja) 2004-03-05 2015-04-08 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア 高脂血症および高コレステロール血症に関連する障害または疾患を、副作用を最小限にしつつ処置するための方法
JO3006B1 (ar) 2005-09-14 2016-09-05 Janssen Pharmaceutica Nv املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك
ES2712052T3 (es) 2008-10-17 2019-05-09 Cymabay Therapeutics Inc Métodos para reducir partículas de LDL pequeñas y densas
MY205872A (en) * 2009-04-29 2024-11-18 Amarin Pharmaceuticals Ie Ltd Pharmaceutical compositions comprising omega-3 fatty acids
EP2552441B1 (en) 2010-03-30 2016-05-04 Novartis AG Uses of dgat1 inhibitors
JOP20200043A1 (ar) 2011-05-10 2017-06-16 Amgen Inc طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول
US20160279085A1 (en) 2013-11-20 2016-09-29 Cymabay Therapeutics, Inc. Treatment of Severe Hyperlipidemia
MX2016006583A (es) 2013-11-20 2016-09-06 Cymabay Therapeutics Inc Tratamiento de hipercolesterolemia familiar homocigotica.
US9486428B2 (en) 2014-03-20 2016-11-08 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
US10272058B2 (en) 2014-03-20 2019-04-30 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
JP6865038B2 (ja) 2014-04-11 2021-04-28 サイマベイ・セラピューティクス・インコーポレイテッドCymaBay Therapeutics,Inc. Nafldおよびnashの治療
CA2951280A1 (en) 2014-06-26 2015-12-30 Cymabay Therapeutics, Inc. Treatment of severe hypertriglyceridemia
US10512622B2 (en) 2017-07-14 2019-12-24 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
UA125600C2 (uk) 2017-09-26 2022-04-27 Сімабей Терапьютікс, Інк. Лікування холестатичного свербежу
EP3880187A1 (en) 2018-11-16 2021-09-22 CymaBay Therapeutics, Inc. Treatment of obesity and its complications
BR112021009038A2 (pt) 2018-11-16 2021-08-10 Cymabay Therapeutics, Inc. tratamento combinado de nafld e nash

Also Published As

Publication number Publication date
RU2018146504A (ru) 2020-07-09
AU2017274293B2 (en) 2022-03-31
US20170340589A1 (en) 2017-11-30
UA122719C2 (uk) 2020-12-28
US20210220305A1 (en) 2021-07-22
RU2765460C2 (ru) 2022-01-31
HRP20220903T1 (hr) 2022-10-14
PL3463328T3 (pl) 2022-10-03
IL263372B2 (en) 2023-06-01
US20190255004A1 (en) 2019-08-22
CA3024155A1 (en) 2017-12-07
EP3463328B1 (en) 2022-06-15
ES2921230T3 (es) 2022-08-22
KR20190015363A (ko) 2019-02-13
SMT202200471T1 (it) 2023-01-13
SG11201810123SA (en) 2018-12-28
EP3463328A1 (en) 2019-04-10
RS63345B1 (sr) 2022-07-29
WO2017209865A1 (en) 2017-12-07
SI3463328T1 (sl) 2022-08-31
US11596614B2 (en) 2023-03-07
PT3463328T (pt) 2022-07-07
US10272058B2 (en) 2019-04-30
ZA201808360B (en) 2020-02-26
US10478411B2 (en) 2019-11-19
IL263372A (en) 2018-12-31
LT3463328T (lt) 2022-08-10
US20210000774A1 (en) 2021-01-07
US11000494B2 (en) 2021-05-11
NZ748721A (en) 2022-04-29
HUE059838T2 (hu) 2023-01-28
KR102408288B1 (ko) 2022-06-10
CY1125465T1 (el) 2025-05-09
JP7079735B2 (ja) 2022-06-02
JP2019518022A (ja) 2019-06-27
US20200061006A1 (en) 2020-02-27
BR112018074147A2 (pt) 2019-03-06
CN109195594A (zh) 2019-01-11
RU2018146504A3 (es) 2020-07-27
MX390417B (es) 2025-03-20
DK3463328T3 (da) 2022-07-04
AU2017274293A1 (en) 2018-12-13
CA3024155C (en) 2023-10-10
US10813895B2 (en) 2020-10-27

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