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MX2018007386A - Sensor in-vitro que utiliza una medicion de impedancia tetrapolar. - Google Patents

Sensor in-vitro que utiliza una medicion de impedancia tetrapolar.

Info

Publication number
MX2018007386A
MX2018007386A MX2018007386A MX2018007386A MX2018007386A MX 2018007386 A MX2018007386 A MX 2018007386A MX 2018007386 A MX2018007386 A MX 2018007386A MX 2018007386 A MX2018007386 A MX 2018007386A MX 2018007386 A MX2018007386 A MX 2018007386A
Authority
MX
Mexico
Prior art keywords
impedance measurement
base layer
electrodes
vitro sensor
sensing electrodes
Prior art date
Application number
MX2018007386A
Other languages
English (en)
Other versions
MX388445B (es
Inventor
E Modzelewski Brent
j paul Patrick
Original Assignee
Trividia Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trividia Health Inc filed Critical Trividia Health Inc
Publication of MX2018007386A publication Critical patent/MX2018007386A/es
Publication of MX388445B publication Critical patent/MX388445B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/026Dielectric impedance spectroscopy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/028Circuits therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/04Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3273Devices therefor, e.g. test element readers, circuitry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3274Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0295Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14535Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring haematocrit
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ecology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)

Abstract

Se proporcionan los sistemas, métodos y dispositivos para determinar una medición de impedancia de una muestra de fluido sobre una tira de prueba que tiene una capa base, al menos dos electrodos de accionamiento colocados sobre la capa base y en comunicación eléctrica con una fuente de corriente (Iac) para hacer fluir una corriente AC proporcionada por la fuente de corriente (Iac) a través de una muestra de fluido entre al menos dos electrodos de accionamiento, y al menos dos electrodos de detección colocados sobre la capa base, y colocados entre al menos dos electrodos de accionamiento, cada uno de al menos dos electrodos de detección está configurado para medir una diferencia en un potencial AC entre los mismos, para determinar una medición de impedancia de la muestra de fluido entre al menos dos electrodos de detección.
MX2018007386A 2015-12-18 2016-12-15 Sensor in-vitro que utiliza una medicion de impedancia tetrapolar. MX388445B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562269277P 2015-12-18 2015-12-18
PCT/US2016/067028 WO2017106560A1 (en) 2015-12-18 2016-12-15 In-vitro sensor using a tetrapolar impedance measurement

Publications (2)

Publication Number Publication Date
MX2018007386A true MX2018007386A (es) 2018-11-09
MX388445B MX388445B (es) 2025-03-19

Family

ID=59057681

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018007386A MX388445B (es) 2015-12-18 2016-12-15 Sensor in-vitro que utiliza una medicion de impedancia tetrapolar.

Country Status (8)

Country Link
US (1) US10718728B2 (es)
EP (1) EP3391036A4 (es)
JP (1) JP2019504310A (es)
CN (2) CN113484382A (es)
AU (1) AU2016370920B2 (es)
MX (1) MX388445B (es)
TW (1) TW201732283A (es)
WO (1) WO2017106560A1 (es)

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* Cited by examiner, † Cited by third party
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TWI609182B (zh) * 2016-11-04 2017-12-21 五鼎生物技術股份有限公司 葡萄糖量測裝置與設備
DE102019000763A1 (de) * 2019-02-02 2020-08-06 Wolfgang Krautschneider Anordnung zur elektrischen Charakterisierung von biologischem Material
WO2020223645A1 (en) * 2019-05-02 2020-11-05 Hudrlik Terrence R Sensor and system for detecting and responding to changes in the displacement current component of impedivity of fluids as an indicator of dielectric constant changes
CN112285171B (zh) * 2020-11-25 2022-09-06 三诺生物传感股份有限公司 一种应用于电化学试条的阻抗测试方法及电化学测量系统
AU2022400944A1 (en) * 2021-11-30 2024-06-13 Trividia Health, Inc. Systems and methods for hematocrit impedance measurement using 4-wire measurement

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JPS5346896U (es) * 1976-09-27 1978-04-20
JPS5441584A (en) * 1977-09-07 1979-04-02 Asahi Medical Co Human body blood current meter
DE3202067C2 (de) * 1982-01-23 1984-06-20 Holger Dr. 5100 Aachen Kiesewetter Vorrichtung zur Bestimmung des Hämatokritwertes
NL8700688A (nl) * 1987-03-24 1988-10-17 Yokogawa Electrofact Bv Werkwijze en inrichting voor het meten van het geleidingsvermogen van een vloeistof met controle van de overgangsweerstand tussen een elektrode en de vloeistof.
US5526808A (en) * 1990-10-04 1996-06-18 Microcor, Inc. Method and apparatus for noninvasively determining hematocrit
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Also Published As

Publication number Publication date
WO2017106560A1 (en) 2017-06-22
CN113484382A (zh) 2021-10-08
EP3391036A4 (en) 2019-07-31
AU2016370920A1 (en) 2018-07-05
AU2016370920B2 (en) 2021-01-14
MX388445B (es) 2025-03-19
TW201732283A (zh) 2017-09-16
JP2019504310A (ja) 2019-02-14
US10718728B2 (en) 2020-07-21
US20170176366A1 (en) 2017-06-22
EP3391036A1 (en) 2018-10-24
CN108496074A (zh) 2018-09-04

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