[go: up one dir, main page]

MX2018005448A - Metodos para la deteccion de apolipoproteinas. - Google Patents

Metodos para la deteccion de apolipoproteinas.

Info

Publication number
MX2018005448A
MX2018005448A MX2018005448A MX2018005448A MX2018005448A MX 2018005448 A MX2018005448 A MX 2018005448A MX 2018005448 A MX2018005448 A MX 2018005448A MX 2018005448 A MX2018005448 A MX 2018005448A MX 2018005448 A MX2018005448 A MX 2018005448A
Authority
MX
Mexico
Prior art keywords
methods
apolipoproteins
detection
isoforms
neurodegenerative
Prior art date
Application number
MX2018005448A
Other languages
English (en)
Other versions
MX382446B (es
Inventor
Rodríguez Martín Andrés
Calero Rueda Olga
Calero Lara Miguel
García Albert Luis
Original Assignee
Centro De Investig Biomedica En Red En Enfermedades Neurodegenerativas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centro De Investig Biomedica En Red En Enfermedades Neurodegenerativas filed Critical Centro De Investig Biomedica En Red En Enfermedades Neurodegenerativas
Publication of MX2018005448A publication Critical patent/MX2018005448A/es
Publication of MX382446B publication Critical patent/MX382446B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/775—Apolipopeptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2835—Movement disorders, e.g. Parkinson, Huntington, Tourette
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Ecology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

La presente invención se relaciona con métodos para la detección y cuantificación de apolipoproteínas y las isoformas de las mismas en una muestra, así como con los métodos predictivos de la probabilidad del desarrollo de enfermedades neurodegenerativas o cardiovasculares basado en los niveles de apolipoproteínas 5 según se determina mediante los métodos de detección de la invención.
MX2018005448A 2015-11-02 2016-11-02 Métodos para la detección de apolipoproteínas. MX382446B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15382537.7A EP3163303A1 (en) 2015-11-02 2015-11-02 Methods for apolipoprotein detection
PCT/EP2016/076457 WO2017076919A2 (en) 2015-11-02 2016-11-02 Methods for apolipoprotein detection

Publications (2)

Publication Number Publication Date
MX2018005448A true MX2018005448A (es) 2019-04-04
MX382446B MX382446B (es) 2025-03-13

Family

ID=54608470

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018005448A MX382446B (es) 2015-11-02 2016-11-02 Métodos para la detección de apolipoproteínas.

Country Status (16)

Country Link
US (1) US20180313854A1 (es)
EP (3) EP3163303A1 (es)
JP (1) JP6994718B2 (es)
KR (1) KR102630558B1 (es)
CN (2) CN108700593A (es)
AU (1) AU2016348558B2 (es)
CA (1) CA3003837A1 (es)
DK (1) DK3274725T3 (es)
ES (1) ES2728268T3 (es)
HU (1) HUE042606T2 (es)
MX (1) MX382446B (es)
PL (1) PL3274725T3 (es)
PT (1) PT3274725T (es)
RU (1) RU2763404C2 (es)
TR (1) TR201904846T4 (es)
WO (1) WO2017076919A2 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102392947B1 (ko) * 2016-07-21 2022-05-03 클리블랜드 하트랩, 아이엔씨. Hdl-관련 단백질 바이오마커 패널 검출
CN112689762B (zh) 2018-06-01 2024-08-23 美国控股实验室公司 用于lc-ms/ms蛋白质组学基因分型的方法和系统
CN109212218A (zh) * 2018-11-07 2019-01-15 李玉民 基于apoa4蛋白胃癌检测试剂盒、及其使用方法
WO2021050880A2 (en) * 2019-09-13 2021-03-18 Northwestern University Biomarkers for amyotrophic lateral sclerosis (als) and motor neuron diseases
CN110780071A (zh) * 2019-11-11 2020-02-11 彭涛 一种乙肝相关肝细胞癌的预后检测试剂盒
CN112375138B (zh) * 2020-11-13 2022-12-13 中元汇吉生物技术股份有限公司 一种重组载脂蛋白e和应用
CN115541568B (zh) * 2021-06-29 2025-07-11 厦门红观生物科技有限公司 一种泪液试纸上ApoJ提取和定量检测方法及其试剂盒和应用
CN117886933A (zh) * 2023-12-28 2024-04-16 上海良润生物医药科技有限公司 一种载脂蛋白e检测试剂及其应用
WO2025219956A1 (en) * 2024-04-18 2025-10-23 Comed Therapeutics Ltd. Compositions and methods for rna delivery to cells

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772549A (en) * 1986-05-30 1988-09-20 Biotechnology Research Partners, Ltd. Polymorphisms related to lipid metabolism: ApoB, ApoCII, ApoE, ApoAIV
US5945289A (en) 1996-12-20 1999-08-31 Lehrer; Steven Method for detecting prostate cancer by apolipoprotein E (Apo-E) genotyping
JP3397066B2 (ja) * 1996-12-27 2003-04-14 富士レビオ株式会社 免疫学的測定方法を用いたアポ蛋白ｅフェノタイプの同定方法
EP1161689A1 (en) * 1999-03-16 2001-12-12 Serex, Inc. Method and device for detection of apo a, apo b and the ratio thereof in saliva
ATE390633T1 (de) 2001-10-04 2008-04-15 Immuno Biological Lab Co Ltd Reagens zum nachweis eines morbus-alzheimer- risikofaktors, nachweiskit dafür und verfahren zum nachweis eines morbus-alzheimer-risikofaktors unter verwendung davon
EP1482897A2 (en) * 2002-02-19 2004-12-08 Ilex Products, Inc. Aminodiphosphonate apolipoprotein e modulators
US20050255498A1 (en) * 2004-01-22 2005-11-17 Genaissance Pharmaceuticals APOC1 genetic markers associated with age of onset of Alzheimer's Disease
JP5229789B2 (ja) * 2007-02-27 2013-07-03 プリマハム株式会社 新規ストレスバイオマーカー及びその用途
WO2009108073A1 (en) * 2008-02-28 2009-09-03 Auckland Uniservices Limited Biomarkers for prediction of preeclampsia and/or cardiovascular disease
ES2364169B1 (es) * 2010-02-09 2012-07-10 CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Titular al 50%) Uso de las isoformas de apo j como biomarcadores de lesión tisular.
US9102717B2 (en) * 2010-03-01 2015-08-11 The J. David Gladstone Institutes Antibody specific for apolipoprotein and methods of use thereof
WO2012006329A2 (en) * 2010-07-06 2012-01-12 Genomind, Llc Apoe4 and apoj biomarker-based prevention and treatment of dementia
US9494606B2 (en) * 2012-05-09 2016-11-15 President And Fellows Of Harvard College Quantification of lipoproteins
ES2759026T3 (es) * 2013-02-26 2020-05-07 Inst Oftalmologico Fernandez Vega S L Método para el diagnóstico de glaucoma basándose en la determinación de niveles de proteínas séricas

Also Published As

Publication number Publication date
US20180313854A1 (en) 2018-11-01
PL3274725T3 (pl) 2019-08-30
ES2728268T3 (es) 2019-10-23
BR112018008749A8 (pt) 2019-02-26
DK3274725T3 (en) 2019-04-23
JP2018533022A (ja) 2018-11-08
AU2016348558B2 (en) 2022-02-24
BR112018008749A2 (pt) 2018-10-30
JP6994718B2 (ja) 2022-01-14
EP3163303A1 (en) 2017-05-03
RU2763404C2 (ru) 2021-12-28
CN108700593A (zh) 2018-10-23
RU2018120081A (ru) 2019-12-05
EP3457140A1 (en) 2019-03-20
CA3003837A1 (en) 2017-05-11
KR102630558B1 (ko) 2024-01-26
MX382446B (es) 2025-03-13
WO2017076919A3 (en) 2017-06-15
CN119199154A (zh) 2024-12-27
TR201904846T4 (tr) 2019-04-22
KR20180081545A (ko) 2018-07-16
WO2017076919A2 (en) 2017-05-11
EP3274725A2 (en) 2018-01-31
HUE042606T2 (hu) 2019-07-29
EP3274725B1 (en) 2019-01-09
AU2016348558A1 (en) 2018-06-21
PT3274725T (pt) 2019-04-30
RU2018120081A3 (es) 2020-03-10

Similar Documents

Publication Publication Date Title
MX2018005448A (es) Metodos para la deteccion de apolipoproteinas.
CL2017002728A1 (es) Método para el tratamiento de cáncer
MX354031B (es) Método y aparato para mostrar el clima.
CO2017005773A2 (es) Composiciones, dispositivos, y métodos de pruebas de sensibilidad del ibs
EP3484994A4 (en) A crispr-cas system for an algal host cell
CL2024000367A1 (es) Anticuerpos antifactor de la coagulación xi.
IL253384B (en) Wafer inspection with focus volumetric method
MX2017008421A (es) Métodos terapéuticos, diagnósticos y pronósticos para el cáncer de vejiga.
MX379111B (es) Método, dispositivo y dispositivo electrónico para calentar un contenedor de un equipo de cocción por inducción.
MX2016001719A (es) Metodos y equipos para predecir el riesgo de tener una enfermedad o evento cardiovascular.
MX2013014153A (es) Biomarcadores paa terapia de inhibidor de hedgehog.
IL253710B (en) Biomarkers for pancreatic cancer and kits and methods for detecting same
EA201790769A1 (ru) Определение уровней гликозаминогликанов методом масс-спектрометрии
Qin Distributivity between semi-uninorms and semi-t-operators
AR102037A1 (es) Procesador y método para el procesamiento de una señal de audio por el uso del análisis truncado o las porciones de solapamiento de la ventana de síntesis
CL2016002632A1 (es) Sistema de calibracion de brazo
IL270863B (en) Repeater defect detection
MX384554B (es) Membrana sensible al magnesio para un electrodo potenciometrico de ion selectivo para medicion de magnesio ionizado y metodos de produccion y uso de la misma.
MX2016012278A (es) Deteccion temprana de preeclampsia.
MX2015015015A (es) Metodo para diagnosticar cancer.
CL2017002967A1 (es) Beta-caseinas a2 y capacidad antioxidante.
MX2016015531A (es) Ensayo de inflamacion oral.
EA201790920A1 (ru) Титрованные экстракты cynara scolymus и их применения
WO2016100745A3 (en) Methods and compositions related to transplant-associated thrombotic microangiopathy
EP3354745A4 (en) BIOMARKER COMPOSITION, DIAGNOSIS KIT AND METHOD FOR PROVIDING INFORMATION