MX2018005218A - Drimenol sintasas iii. - Google Patents
Drimenol sintasas iii.Info
- Publication number
- MX2018005218A MX2018005218A MX2018005218A MX2018005218A MX2018005218A MX 2018005218 A MX2018005218 A MX 2018005218A MX 2018005218 A MX2018005218 A MX 2018005218A MX 2018005218 A MX2018005218 A MX 2018005218A MX 2018005218 A MX2018005218 A MX 2018005218A
- Authority
- MX
- Mexico
- Prior art keywords
- drimenol
- iii
- polypeptides
- polypeptide
- useful
- Prior art date
Links
- 101000924190 Aspergillus calidoustus Drimenol cyclase drtB Proteins 0.000 title 1
- HMWSKUKBAWWOJL-KCQAQPDRSA-N drimenol Chemical compound CC1(C)CCC[C@]2(C)[C@@H](CO)C(C)=CC[C@H]21 HMWSKUKBAWWOJL-KCQAQPDRSA-N 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- HMWSKUKBAWWOJL-UHFFFAOYSA-N Drimenol Natural products CC1(C)CCCC2(C)C(CO)C(C)=CCC21 HMWSKUKBAWWOJL-UHFFFAOYSA-N 0.000 abstract 2
- HMWSKUKBAWWOJL-YDHLFZDLSA-N drimentol Natural products OC[C@H]1C(C)=CC[C@H]2C(C)(C)CCC[C@@]12C HMWSKUKBAWWOJL-YDHLFZDLSA-N 0.000 abstract 2
- VWFJDQUYCIWHTN-YFVJMOTDSA-N 2-trans,6-trans-farnesyl diphosphate Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\CO[P@](O)(=O)OP(O)(O)=O VWFJDQUYCIWHTN-YFVJMOTDSA-N 0.000 abstract 1
- VWFJDQUYCIWHTN-UHFFFAOYSA-N Farnesyl pyrophosphate Natural products CC(C)=CCCC(C)=CCCC(C)=CCOP(O)(=O)OP(O)(O)=O VWFJDQUYCIWHTN-UHFFFAOYSA-N 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/07—Diphosphoric monoester hydrolases (3.1.7)
- C12Y301/07007—Drimenol cyclase (3.1.7.7)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente invención describe un método para producir drimenol y/o derivados de drimenol poniendo en contacto un polipéptido con pirofosfato de farnesilo. También se proporciona una secuencia de aminoácidos de un polipéptido útil en los métodos de la invención y un ácido nucleico que codifica el polipéptido de la invención. El método proporciona además células hospederas u organismos modificados genéticamente para expresar los polipéptidos de la invención y que es útil para producir drimenol y/o derivados de drimenol.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2015093897 | 2015-11-05 | ||
| PCT/EP2016/076874 WO2017077125A1 (en) | 2015-11-05 | 2016-11-07 | Drimenol synthases iii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018005218A true MX2018005218A (es) | 2018-08-01 |
Family
ID=57394532
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018005218A MX2018005218A (es) | 2015-11-05 | 2016-11-07 | Drimenol sintasas iii. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10550409B2 (es) |
| EP (1) | EP3371304B1 (es) |
| JP (1) | JP6856639B2 (es) |
| CN (1) | CN108473972B (es) |
| BR (1) | BR112018009245A2 (es) |
| CA (1) | CA3001638A1 (es) |
| ES (1) | ES2861444T3 (es) |
| MX (1) | MX2018005218A (es) |
| WO (1) | WO2017077125A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11293037B2 (en) | 2017-06-02 | 2022-04-05 | Firmenich Sa | Method for producing albicanol and/or drimenol |
| US11345907B2 (en) | 2018-05-29 | 2022-05-31 | Firmenich Sa | Method for producing albicanol compounds |
| CN112789354B (zh) * | 2018-10-15 | 2024-11-12 | 弗门尼舍有限公司 | 用于产生乙酸补身烷基酯化合物的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US807407A (en) * | 1904-02-05 | 1905-12-12 | Chicago Pneumatic Tool Co | Calking process. |
| CN1703507B (zh) * | 2002-10-04 | 2010-09-29 | 弗门尼舍有限公司 | 倍半萜烯合成酶及其使用方法 |
| EP2768955A1 (en) * | 2011-10-19 | 2014-08-27 | Keygene N.V. | Methods and compositions for producing drimenol |
| WO2015176959A1 (en) * | 2014-05-21 | 2015-11-26 | Firmenich S.A. | Drimenol synthases and method for producing drimenol |
| BR112016025905B1 (pt) * | 2014-05-06 | 2024-01-09 | Firmenich S.A | Drimenol sintases ii |
-
2016
- 2016-11-07 CA CA3001638A patent/CA3001638A1/en not_active Abandoned
- 2016-11-07 MX MX2018005218A patent/MX2018005218A/es unknown
- 2016-11-07 US US15/772,567 patent/US10550409B2/en active Active
- 2016-11-07 BR BR112018009245A patent/BR112018009245A2/pt active Search and Examination
- 2016-11-07 CN CN201680064241.XA patent/CN108473972B/zh active Active
- 2016-11-07 ES ES16801149T patent/ES2861444T3/es active Active
- 2016-11-07 EP EP16801149.2A patent/EP3371304B1/en active Active
- 2016-11-07 JP JP2018522765A patent/JP6856639B2/ja not_active Expired - Fee Related
- 2016-11-07 WO PCT/EP2016/076874 patent/WO2017077125A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP6856639B2 (ja) | 2021-04-07 |
| CN108473972B (zh) | 2022-08-09 |
| ES2861444T3 (es) | 2021-10-06 |
| US20190093131A1 (en) | 2019-03-28 |
| EP3371304A1 (en) | 2018-09-12 |
| CA3001638A1 (en) | 2017-05-11 |
| CN108473972A (zh) | 2018-08-31 |
| BR112018009245A2 (pt) | 2018-11-06 |
| US10550409B2 (en) | 2020-02-04 |
| JP2018536400A (ja) | 2018-12-13 |
| WO2017077125A1 (en) | 2017-05-11 |
| EP3371304B1 (en) | 2021-01-06 |
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