MX2018004979A - Compuesto piranodipiridinico. - Google Patents
Compuesto piranodipiridinico.Info
- Publication number
- MX2018004979A MX2018004979A MX2018004979A MX2018004979A MX2018004979A MX 2018004979 A MX2018004979 A MX 2018004979A MX 2018004979 A MX2018004979 A MX 2018004979A MX 2018004979 A MX2018004979 A MX 2018004979A MX 2018004979 A MX2018004979 A MX 2018004979A
- Authority
- MX
- Mexico
- Prior art keywords
- pyranodipyridine
- compound
- pyranodipyridine compound
- formulas
- xxii
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
- C07D491/147—Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Compuestos representados por las fórmulas (I) - (XXII) o sus sales farmacéuticamente aceptables: (ver Fórmulas).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015222805 | 2015-11-13 | ||
| PCT/JP2016/083211 WO2017082288A1 (ja) | 2015-11-13 | 2016-11-09 | ピラノジピリジン化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2018004979A true MX2018004979A (es) | 2018-09-07 |
| MX380080B MX380080B (es) | 2025-03-11 |
Family
ID=58691331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018004979A MX380080B (es) | 2015-11-13 | 2016-11-09 | Compuesto piranodipiridínico. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US9738656B2 (es) |
| EP (1) | EP3378863A4 (es) |
| JP (1) | JP6353173B2 (es) |
| KR (1) | KR20180080201A (es) |
| CN (1) | CN108349989B (es) |
| AR (1) | AR106647A1 (es) |
| AU (1) | AU2016351424B2 (es) |
| BR (1) | BR112018008006A2 (es) |
| CA (1) | CA3002930A1 (es) |
| CL (1) | CL2018001067A1 (es) |
| CO (1) | CO2018004213A2 (es) |
| HK (1) | HK1255832A1 (es) |
| IL (1) | IL258952B (es) |
| JO (1) | JO3742B1 (es) |
| MA (1) | MA43275A (es) |
| MX (1) | MX380080B (es) |
| MY (1) | MY185971A (es) |
| PE (1) | PE20181008A1 (es) |
| PH (1) | PH12018500903A1 (es) |
| RU (1) | RU2743998C2 (es) |
| SG (1) | SG11201803433TA (es) |
| TW (1) | TWI644916B (es) |
| UA (1) | UA122241C2 (es) |
| WO (1) | WO2017082288A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2018207715A1 (ja) * | 2017-05-09 | 2020-03-12 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ピラノジピリジン化合物の結晶 |
| WO2018207729A1 (ja) * | 2017-05-09 | 2018-11-15 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ピラノジピリジン化合物を含有する治療剤 |
| JP7217259B2 (ja) * | 2017-07-26 | 2023-02-02 | エイチジーアンドエイチ ファーマスーティカルズ（ピーティワイ）リミテッド | てんかん及び関連疾患を患う患者の予防及び治療のためのメセンブレノール及び／又はメセンブラノール |
| JP7250686B2 (ja) * | 2017-10-06 | 2023-04-03 | 武田薬品工業株式会社 | 複素環化合物 |
| US11447488B2 (en) | 2017-10-06 | 2022-09-20 | Takeda Pharmaceutical Company Limited | Heterocyclic compounds |
| CN111801096B (zh) | 2018-03-20 | 2024-03-05 | 卫材R&D管理有限公司 | 癫痫治疗剂 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0102046A1 (en) * | 1982-08-26 | 1984-03-07 | Schering Corporation | Tricyclic lactams, method for making them, pharmaceutical compositions containing them |
| US4511569A (en) | 1982-08-26 | 1985-04-16 | Schering Corporation | Tricyclic lactams and derivatives useful in increasing cardiac contractility |
| US4666916A (en) | 1985-11-08 | 1987-05-19 | Ciba-Geigy Corporation | Hexahydro-(1)-benzo-(pyrano and thiopyrano) (4,3-C)pyridines, useful as serotin-2 blocking agents |
| FR2717811B1 (fr) * | 1994-03-28 | 1996-04-26 | Rhone Poulenc Rorer Sa | Dérivés d'imidazo[1,2-a]pyrazine-4-one, leur préparation et les médicaments les contenant. |
| HU229553B1 (en) * | 2000-06-12 | 2014-01-28 | Eisai R & D Man Co | 1,2-dihydropyridine compound, process for preparation of the same and use thereof |
| IL154709A0 (en) * | 2000-09-18 | 2003-10-31 | Eisai Co Ltd | Pyridazinone and triazinone derivatives and pharmaceutical compositions containing the same |
| RU2279428C2 (ru) * | 2000-09-18 | 2006-07-10 | Эйсай Ко., Лтд. | Производные пиридазинона и триазинона и их применение в качестве фармацевтических препаратов |
-
2016
- 2016-11-09 AU AU2016351424A patent/AU2016351424B2/en not_active Ceased
- 2016-11-09 MX MX2018004979A patent/MX380080B/es unknown
- 2016-11-09 WO PCT/JP2016/083211 patent/WO2017082288A1/ja not_active Ceased
- 2016-11-09 SG SG11201803433TA patent/SG11201803433TA/en unknown
- 2016-11-09 BR BR112018008006-3A patent/BR112018008006A2/pt active Search and Examination
- 2016-11-09 JP JP2017550353A patent/JP6353173B2/ja not_active Expired - Fee Related
- 2016-11-09 UA UAA201804486A patent/UA122241C2/uk unknown
- 2016-11-09 KR KR1020187011535A patent/KR20180080201A/ko not_active Withdrawn
- 2016-11-09 PE PE2018000574A patent/PE20181008A1/es unknown
- 2016-11-09 TW TW105136376A patent/TWI644916B/zh not_active IP Right Cessation
- 2016-11-09 MY MYPI2018701650A patent/MY185971A/en unknown
- 2016-11-09 HK HK18114908.2A patent/HK1255832A1/zh unknown
- 2016-11-09 US US15/346,912 patent/US9738656B2/en not_active Expired - Fee Related
- 2016-11-09 EP EP16864249.4A patent/EP3378863A4/en not_active Withdrawn
- 2016-11-09 JO JOP/2016/0238A patent/JO3742B1/ar active
- 2016-11-09 CA CA3002930A patent/CA3002930A1/en not_active Abandoned
- 2016-11-09 MA MA043275A patent/MA43275A/fr unknown
- 2016-11-09 RU RU2018115716A patent/RU2743998C2/ru active
- 2016-11-09 CN CN201680062780.XA patent/CN108349989B/zh not_active Expired - Fee Related
- 2016-11-10 AR ARP160103430A patent/AR106647A1/es unknown
-
2018
- 2018-04-20 CO CONC2018/0004213A patent/CO2018004213A2/es unknown
- 2018-04-23 CL CL2018001067A patent/CL2018001067A1/es unknown
- 2018-04-26 IL IL258952A patent/IL258952B/en active IP Right Grant
- 2018-04-26 PH PH12018500903A patent/PH12018500903A1/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3873903T3 (da) | Substituerede 6-azabenzimidazolforbindelser som hpk1-hæmmere | |
| DK3761790T3 (da) | Picolinamider som fungicider | |
| AR101995A1 (es) | COMPUESTOS ANTAGONISTAS DE INTEGRINA avb6 | |
| DK3768674T3 (da) | Aminopyrimidinderivater som ctps1-hæmmere | |
| MX2017002670A (es) | Inhibidores de glucosidasa. | |
| EA201891024A1 (ru) | Соединения-ингибиторы tank-связывающей киназы | |
| MX380394B (es) | Compuesto novedoso de bifenilo o una sal del mismo. | |
| CL2016001458A1 (es) | Derivado de sulfonamida o sales de adición de ácido farmaceuticamente aceptables del mismo. | |
| CO2018004213A2 (es) | Compuesto piranodipiridínico | |
| EA201692203A1 (ru) | Соединения, ингибирующие tank-связывающую киназу | |
| EA201591634A1 (ru) | Дигидропиридопиримидиновые соединения | |
| GEAP201814347A (en) | Substituted dihydroisoquinoline compounds | |
| EA201791684A1 (ru) | Селективные ингибиторы bace1 | |
| EA201690764A1 (ru) | Ингибитор грелин-o-ацилтрансферазы | |
| DK3762368T3 (da) | Aminopyrazindiolforbindelser som pi3k-y-inhibitorer | |
| AR105967A1 (es) | Sales de un inhibidor de pim quinasa | |
| CL2020000376A1 (es) | Compuesto pentacíclico. | |
| HUE053267T2 (hu) | Bisz-vegyületek optikailag aktív eszközökhöz | |
| MX387796B (es) | Compuestos de aminocarbonilcarbamato. | |
| MX2018013133A (es) | Compuesto de pirazolo[1,5-a]pirimidina. | |
| DK3552017T3 (da) | Forbindelser, der er anvendelige som ripk1-inhibitorer | |
| CR20180089A (es) | Compuestos útiles para inhibir a ror-gamma-t | |
| EA201790687A1 (ru) | Хинолинкарбоксамиды для применения в лечении множественной миеломы | |
| EA201990313A1 (ru) | Производное триазолопиразинона, пригодное в качестве ингибитора фдэ1 человека | |
| EA201990238A1 (ru) | ФОСФОРСОДЕРЖАЩИЕ ПРОЛЕКАРСТВА СТИМУЛЯТОРОВ sGC |