[go: up one dir, main page]

MX2018004029A - Deteccion de analitos con multiples sustratos. - Google Patents

Deteccion de analitos con multiples sustratos.

Info

Publication number
MX2018004029A
MX2018004029A MX2018004029A MX2018004029A MX2018004029A MX 2018004029 A MX2018004029 A MX 2018004029A MX 2018004029 A MX2018004029 A MX 2018004029A MX 2018004029 A MX2018004029 A MX 2018004029A MX 2018004029 A MX2018004029 A MX 2018004029A
Authority
MX
Mexico
Prior art keywords
analyte
binding
agent
analyte detection
multiple substrates
Prior art date
Application number
MX2018004029A
Other languages
English (en)
Inventor
James Sheehan Antony
Francis CROUCH Michael
Original Assignee
Tgr Biosciences Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tgr Biosciences Pty Ltd filed Critical Tgr Biosciences Pty Ltd
Publication of MX2018004029A publication Critical patent/MX2018004029A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nanotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

La presente descripción provee métodos y/o kits para detectar un analito en una muestra. Algunas modalidades proveen un sistema de detección de analitos, kit y método para usar el mismo, que comprende: un primer agente que comprende al menos una etiqueta y capaz de unirse al analito; un segundo agente covalentemente unido a una pluralidad de etiquetas de póptido y capaz de unirse al analito; una primera perla que comprende un aglutinante capaz de unirse con el primer agente etiquetado; y una segunda perla que comprende un agente anti-póptido capaz de unirse con al menos una de la pluralidad de etiquetas de póptido covalentemente unidas.
MX2018004029A 2015-10-02 2016-09-30 Deteccion de analitos con multiples sustratos. MX2018004029A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562236676P 2015-10-02 2015-10-02
US201562237522P 2015-10-05 2015-10-05
PCT/IB2016/001981 WO2017068431A1 (en) 2015-10-02 2016-09-30 Analyte detection with multiple substrates

Publications (1)

Publication Number Publication Date
MX2018004029A true MX2018004029A (es) 2018-07-06

Family

ID=58446765

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018004029A MX2018004029A (es) 2015-10-02 2016-09-30 Deteccion de analitos con multiples sustratos.

Country Status (9)

Country Link
US (3) US20180275121A1 (es)
EP (1) EP3356822B1 (es)
JP (1) JP2018533017A (es)
CN (1) CN108603877A (es)
AU (1) AU2016341539A1 (es)
CA (1) CA3000584A1 (es)
HK (1) HK1254374A1 (es)
MX (1) MX2018004029A (es)
WO (1) WO2017068431A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011057347A1 (en) 2009-11-12 2011-05-19 Tgr Biosciences Pty Ltd Analyte detection
WO2021070218A1 (ja) * 2019-10-07 2021-04-15 ナノティス株式会社 試料中の被検出物質を検出する方法
US20220205993A1 (en) * 2020-12-28 2022-06-30 Industrial Technology Research Institute Detection method of multiple analytes
CN118043347A (zh) * 2021-09-30 2024-05-14 美国西门子医学诊断股份有限公司 用于抗sars-cov-2抗体的双重免疫测定的组合物、试剂盒和方法
WO2025235476A2 (en) * 2024-05-06 2025-11-13 Beckman Coulter, Inc. Calibration independent immunoassay systems and methods for comparative analyte detection

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE177842T1 (de) 1993-09-03 1999-04-15 Behringwerke Ag Fluoreszenz-sauerstoffkanalisation-immunteste
JP2005534286A (ja) * 2002-03-21 2005-11-17 サネシス ファーマシューティカルズ， インコーポレイテッド キナーゼインヒビターの同定
DE10226011A1 (de) * 2002-06-12 2004-01-08 Aventis Pharma Deutschland Gmbh HTS-fähiges Verfahren und Testsystem zur Ermittlung der Wechselwirkung zwischen c-reaktivem Protein und an C-reaktives Protein bindenden Komponenten
US20030232394A1 (en) 2002-06-12 2003-12-18 Aventis Pharma Deutschland Gmbh High throughput screening method and assay system for determining the interaction between C-reactive protein and components binding to it
BRPI0819693A2 (pt) * 2007-11-30 2020-08-18 Glaxo Group Limited Construção de ligação de antígeno, método para tratar um paciente que sofre de câncer ou uma doença inflamatória, sequência de polinucleotídeo, polinucleotídeo, célula hospedeira transformada ou transfectada recombinante, método para produziruma construção de ligação de antígeno, e, composição farmacêutica
EP2398868B1 (en) * 2009-02-20 2016-06-15 Perkinelmer Biosignal, Inc. Multiplex assay methods and compositions
JP5770161B2 (ja) * 2009-04-06 2015-08-26 ノヴォ ノルディスク アー／エス 血小板への第ｖｉｉｉ因子タンパク質の標的送達
WO2011057347A1 (en) 2009-11-12 2011-05-19 Tgr Biosciences Pty Ltd Analyte detection
DK2786150T3 (en) 2011-03-31 2018-11-05 Tgr Biosciences Pty Ltd DETECTION OF MULTIPLE ANALYTES
WO2012129610A1 (en) * 2011-03-31 2012-10-04 Tgr Biosciences Pty Ltd One-step immunoassay detection of analytes
GB201403875D0 (en) * 2014-03-05 2014-04-16 Cantargia Ab Novel antibodies and uses thereof
WO2016029220A1 (en) * 2014-08-22 2016-02-25 Nectagen, Inc. Affinity proteins and uses thereof
CN104897652B (zh) * 2015-03-19 2017-08-25 杭州金溪生物技术有限公司 一步均相化学发光法进行小分子检测的方法及所用微粒

Also Published As

Publication number Publication date
EP3356822A4 (en) 2019-07-03
EP3356822B1 (en) 2021-10-27
US20170097339A1 (en) 2017-04-06
CN108603877A (zh) 2018-09-28
US20180275121A1 (en) 2018-09-27
CA3000584A1 (en) 2017-04-27
AU2016341539A1 (en) 2018-04-26
JP2018533017A (ja) 2018-11-08
EP3356822A1 (en) 2018-08-08
US20180136202A1 (en) 2018-05-17
HK1254374A1 (zh) 2019-07-19
WO2017068431A1 (en) 2017-04-27

Similar Documents

Publication Publication Date Title
MX2020014089A (es) Metodos, kits y aparato para expandir una poblacion de celulas.
BR112014025384A8 (pt) método e sistema para executar ensaio automatizado e métodos para executar teste reflexivo em vários exemplares
MY170164A (en) Aptamer-based multiplexed assays
EP4365597A3 (en) Methods of assaying proteins
SG10201903822XA (en) Method for the enrichment of circulating tumor dna
MX2018004029A (es) Deteccion de analitos con multiples sustratos.
HK1214830A1 (zh) 新型ntrk1融合分子及其应用
EP4234716A3 (en) Methods for determining spatial patterns of biological targets in a sample
HK1223659A1 (zh) 基於可多重标签的报告系统
EP4270006A3 (en) General detection and isolation of specific cells by binding of labeled molecules
EP4249605A3 (en) Methods for analyte detection
WO2014106004A3 (en) High-throughput system and method for identifying antibodies having specific antigen binding activities
EP4461824A3 (en) Detection kit or device and detection method for biliary tract cancer
ZA202002415B (en) Detection of symmetrical dimethylarginine
SG10201807867XA (en) Simultaneous detection of target protein and target nucleic acids in a single cell
WO2012170206A3 (en) Color-producing diagnostic systems, reagents and methods
WO2014160903A3 (en) Biological sample processing
GB2542576A (en) Method and kit of detecting the absence of micro-oranisms
GB201014028D0 (en) In-situ reagent
MX369610B (es) Metodos, dispositivos y sistemas para analisis de muestras.
MX2020006728A (es) Metodos para medir analito y/o proteina en muestras biologicas.
WO2015184321A3 (en) Rare molecule detection
HK1205558A1 (zh) 用於宫颈癌的检测和预後的方法和生物标志物
EA201500377A1 (ru) Способ обнаружения анализируемого вещества и определение его концентрации с использованием намагничиваемых гранул
BR112016015537A2 (pt) métodos e kits para detectar a presença de sequência polinucleotídea da e. histolytica em amostra