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MX2018003174A - Metodos para tratar enfermedades inflamatorias. - Google Patents

Metodos para tratar enfermedades inflamatorias.

Info

Publication number
MX2018003174A
MX2018003174A MX2018003174A MX2018003174A MX2018003174A MX 2018003174 A MX2018003174 A MX 2018003174A MX 2018003174 A MX2018003174 A MX 2018003174A MX 2018003174 A MX2018003174 A MX 2018003174A MX 2018003174 A MX2018003174 A MX 2018003174A
Authority
MX
Mexico
Prior art keywords
methods
inflammatory diseases
treat inflammatory
diseases
treat
Prior art date
Application number
MX2018003174A
Other languages
English (en)
Inventor
Bettina Galler Annette
John Padula Steven
Lalovic Bojan
Visvanathan Sudha
Scholl Paul
Otto Boecher Wulf
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MX2018003174A publication Critical patent/MX2018003174A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515Complete light chain, i.e. VL + CL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Esta invención se refiere generalmente a métodos para el tratamiento de enfermedades relacionadas con IL-23, en particular, enfermedades inflamatorias, tales como la enfermedad de Crohn, que utilizan anticuerpos anti-IL-23A.
MX2018003174A 2015-09-18 2016-09-15 Metodos para tratar enfermedades inflamatorias. MX2018003174A (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562220410P 2015-09-18 2015-09-18
US201562235654P 2015-10-01 2015-10-01
US201662295643P 2016-02-16 2016-02-16
US201662328863P 2016-04-28 2016-04-28
US201662335242P 2016-05-12 2016-05-12
US201662339192P 2016-05-20 2016-05-20
PCT/US2016/051844 WO2017048901A1 (en) 2015-09-18 2016-09-15 Methods of treating inflammatory diseases

Publications (1)

Publication Number Publication Date
MX2018003174A true MX2018003174A (es) 2018-05-17

Family

ID=57003593

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2018003174A MX2018003174A (es) 2015-09-18 2016-09-15 Metodos para tratar enfermedades inflamatorias.
MX2022015250A MX2022015250A (es) 2015-09-18 2018-03-14 Un anticuerpo anti-il-23a para usarse en el tratamiento de la enfermedad de crohn.
MX2022015248A MX2022015248A (es) 2015-09-18 2018-03-14 Un anticuerpo anti-il-23a para usarse en el tratamiento de la enfermedad de crohn.

Family Applications After (2)

Application Number Title Priority Date Filing Date
MX2022015250A MX2022015250A (es) 2015-09-18 2018-03-14 Un anticuerpo anti-il-23a para usarse en el tratamiento de la enfermedad de crohn.
MX2022015248A MX2022015248A (es) 2015-09-18 2018-03-14 Un anticuerpo anti-il-23a para usarse en el tratamiento de la enfermedad de crohn.

Country Status (16)

Country Link
US (1) US20170081402A1 (es)
EP (1) EP3350221A1 (es)
JP (6) JP6668461B2 (es)
KR (2) KR20180053395A (es)
CN (1) CN108026168A (es)
AU (2) AU2016323152A1 (es)
BR (1) BR112018003526A2 (es)
CA (1) CA2996645A1 (es)
CL (1) CL2018000597A1 (es)
EA (1) EA201890747A1 (es)
HK (1) HK1252037A1 (es)
IL (2) IL302197A (es)
MX (3) MX2018003174A (es)
PH (2) PH12022550515A1 (es)
TW (2) TWI811716B (es)
WO (1) WO2017048901A1 (es)

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MX2019000046A (es) 2010-11-04 2023-10-05 Boehringer Ingelheim Int Anticuerpos anti-il-23.
CN104507497B (zh) 2012-05-03 2018-10-19 勃林格殷格翰国际有限公司 抗IL-23p19抗体
WO2016014775A1 (en) 2014-07-24 2016-01-28 Boehringer Ingelheim International Gmbh Biomarkers useful in the treatment of il-23a related diseases
IL307578A (en) 2015-02-04 2023-12-01 Boehringer Ingelheim Int Methods of treating inflammatory diseases
TWI811716B (zh) * 2015-09-18 2023-08-11 德商百靈佳殷格翰國際股份有限公司 治療發炎性疾病之方法
EP3526252A2 (en) * 2016-10-14 2019-08-21 Boehringer Ingelheim International GmbH Methods of treating diseases with il-23a antibody
US20190269757A1 (en) 2018-03-05 2019-09-05 Janssen Biotech, Inc. Methods of Treating Crohn's Disease with Anti-IL23 Specific Antibody
WO2019246312A1 (en) * 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
TWI850365B (zh) * 2019-04-22 2024-08-01 美商美國禮來大藥廠 治療克隆氏症(crohn's disease)的方法
MX2021014302A (es) 2019-05-23 2022-01-04 Janssen Biotech Inc Metodo para tratar la enfermedad inflamatoria del intestino con una terapia de combinacion de anticuerpos contra il-23 y tnf alfa.
CN112578123B (zh) * 2019-09-27 2022-10-25 成都中医药大学 检测粪钙卫蛋白含量的试剂在制备子宫病变筛查试剂盒中的用途
BR112022023489A2 (pt) 2020-05-21 2023-03-14 Janssen Biotech Inc Método de tratamento de doença inflamatória intestinal com uma terapia de combinação de anticorpos para il-23 e tnf-alfa
TW202241506A (zh) 2021-01-06 2022-11-01 美商艾伯維有限公司 治療克羅恩氏病及潰瘍性結腸炎之方法
AU2024304477A1 (en) * 2023-06-16 2026-01-22 Innovent Biologics (Suzhou) Co., Ltd. Use of recombinant anti-interleukin 23p19 subunit antibody in treating inflammatory bowel disease
TW202540171A (zh) 2024-02-06 2025-10-16 美商派拉岡醫療公司 Il-23抗體組合物及使用方法

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Also Published As

Publication number Publication date
CN108026168A (zh) 2018-05-11
AU2023203530A1 (en) 2023-07-06
KR20180053395A (ko) 2018-05-21
MX2022015248A (es) 2023-01-11
EP3350221A1 (en) 2018-07-25
IL302197A (en) 2023-06-01
TW201722474A (zh) 2017-07-01
TWI811716B (zh) 2023-08-11
NZ739608A (en) 2025-05-30
HK1252037A1 (zh) 2019-05-10
CA2996645A1 (en) 2017-03-23
KR20240170593A (ko) 2024-12-03
CL2018000597A1 (es) 2018-07-27
JP2020100644A (ja) 2020-07-02
JP2020100643A (ja) 2020-07-02
JP2022046624A (ja) 2022-03-23
JP6668461B2 (ja) 2020-03-18
JP2024096863A (ja) 2024-07-17
JP2018527380A (ja) 2018-09-20
AU2016323152A1 (en) 2018-02-22
TWI733695B (zh) 2021-07-21
JP7000476B2 (ja) 2022-02-04
TW202138008A (zh) 2021-10-16
JP2022088478A (ja) 2022-06-14
JP7477492B2 (ja) 2024-05-01
BR112018003526A2 (pt) 2018-09-25
IL257561A (en) 2018-04-30
MX2022015250A (es) 2023-01-11
NZ780210A (en) 2025-05-30
EA201890747A1 (ru) 2018-10-31
PH12022550515A1 (en) 2023-02-27
WO2017048901A1 (en) 2017-03-23
US20170081402A1 (en) 2017-03-23
PH12018500578A1 (en) 2018-09-10

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