MX2018002906A - Metodos de tratamiento de trastornos del desarrollo con pipradrol. - Google Patents
Metodos de tratamiento de trastornos del desarrollo con pipradrol.Info
- Publication number
- MX2018002906A MX2018002906A MX2018002906A MX2018002906A MX2018002906A MX 2018002906 A MX2018002906 A MX 2018002906A MX 2018002906 A MX2018002906 A MX 2018002906A MX 2018002906 A MX2018002906 A MX 2018002906A MX 2018002906 A MX2018002906 A MX 2018002906A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- pipradrol
- developmental disorders
- treating developmental
- syndrome
- Prior art date
Links
- 208000012239 Developmental disease Diseases 0.000 title abstract 2
- XSWHNYGMWWVAIE-UHFFFAOYSA-N pipradrol Chemical compound C=1C=CC=CC=1C(C=1C=CC=CC=1)(O)C1CCCCN1 XSWHNYGMWWVAIE-UHFFFAOYSA-N 0.000 title abstract 2
- 229960000753 pipradrol Drugs 0.000 title abstract 2
- 201000006792 Lennox-Gastaut syndrome Diseases 0.000 abstract 2
- 206010052075 Acquired epileptic aphasia Diseases 0.000 abstract 1
- 201000007547 Dravet syndrome Diseases 0.000 abstract 1
- 201000005802 Landau-Kleffner Syndrome Diseases 0.000 abstract 1
- 208000036572 Myoclonic epilepsy Diseases 0.000 abstract 1
- 206010073677 Severe myoclonic epilepsy of infancy Diseases 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se proporcionan métodos para tratar trastornos del desarrollo administrando una composición farmacéutica de pipradrol o una sal farmacéuticamente aceptable del mismo. Los métodos se pueden usar para tratar condiciones como epilepsia, síndrome de Landau-Kleffner, síndrome de Lennox-Gastaut (LGS) y el síndrome de Dravet.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562215831P | 2015-09-09 | 2015-09-09 | |
| US14/876,110 US9351968B1 (en) | 2015-09-09 | 2015-10-06 | Methods of treating developmental disorders using pipradrol |
| US15/147,429 US20170065572A1 (en) | 2015-09-09 | 2016-05-05 | Methods of treating developmental disorders using pipradrol |
| PCT/US2016/050702 WO2017044578A1 (en) | 2015-09-09 | 2016-09-08 | Methods of treating developmental disorders using pipradrol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018002906A true MX2018002906A (es) | 2018-06-08 |
Family
ID=56027680
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018002906A MX2018002906A (es) | 2015-09-09 | 2016-09-08 | Metodos de tratamiento de trastornos del desarrollo con pipradrol. |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US9351968B1 (es) |
| EP (1) | EP3331527A4 (es) |
| JP (1) | JP2018528215A (es) |
| KR (1) | KR20180081710A (es) |
| CN (1) | CN108366999A (es) |
| AU (1) | AU2016318943A1 (es) |
| BR (1) | BR112018004680A2 (es) |
| CA (1) | CA2997923A1 (es) |
| HK (1) | HK1255132A1 (es) |
| IL (3) | IL257944B (es) |
| MX (1) | MX2018002906A (es) |
| WO (1) | WO2017044578A1 (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9682069B2 (en) | 2015-07-17 | 2017-06-20 | Ovid Therapeutics Inc | Methods of treating Dravet syndrome |
| IL256912B2 (en) | 2015-07-17 | 2024-01-01 | Ovid Therapeutics Inc | Methods of treating developmental disorders with gaboxadol |
| US9351968B1 (en) | 2015-09-09 | 2016-05-31 | Ovid Therapeutics Inc | Methods of treating developmental disorders using pipradrol |
| CA3002831C (en) | 2015-10-22 | 2024-04-16 | Cavion, Inc. | Methods for treating angelman syndrome and related disorders |
| KR20190013737A (ko) | 2016-05-26 | 2019-02-11 | 오비드 테라퓨틱스 인크. | 피프라드롤을 이용한 행동 증후군들의 치료 방법들 |
| CN109715151A (zh) | 2016-08-11 | 2019-05-03 | 奥维德医疗公司 | 用于治疗癫痫性紊乱的方法和组合物 |
| US10071083B2 (en) | 2017-02-03 | 2018-09-11 | Ovid Therapeutics Inc | Use of gaboxadol in the treatment of tinnitus |
| SG11201909960UA (en) | 2017-04-26 | 2019-11-28 | Cavion Inc | Methods for improving memory and cognition and for treating memory and cognitive disorders |
| SG11201909963YA (en) * | 2017-04-26 | 2019-11-28 | Cavion Inc | Methods for treating dravet syndrome |
| AU2018309049A1 (en) | 2017-08-04 | 2020-02-27 | Ovid Therapeutics Inc. | Use of gaboxadol in the treatment of diabetes and related conditions |
| IL274431B2 (en) * | 2017-11-14 | 2024-06-01 | Sk Biopharmaceuticals Co Ltd | Use of carbamate compound for reducing or treating developmental disorders including fragile x syndrome, angelman syndrome or rett syndrome |
| EP3833351A4 (en) | 2018-09-20 | 2021-10-13 | Ovid Therapeutics Inc. | USE OF GABOXADOL FOR THE TREATMENT OF GILLES DE LA TOURETTE SYNDROME, TICS AND STATTING |
| BR112021006398A2 (pt) | 2018-10-03 | 2021-07-06 | Cavion Inc | tratamento de tremor essencial usando (r)-2-(4-isopropilfenil)-n-(1-(5-(2,2,2-trifluoretoxi)piridin-2-il)etil) acetamida |
| WO2020106927A1 (en) | 2018-11-21 | 2020-05-28 | Certego Therapeutics | Gaboxadol for reducing risk of suicide and rapid relief of depression |
| US11690829B2 (en) | 2018-12-17 | 2023-07-04 | Ovid Therapeutics Inc. | Use of gaboxadol for the treatment of non-24 hour sleep-wake disorder |
| IL298334A (en) | 2020-05-20 | 2023-01-01 | Certego Therapeutics Inc | Ring deuterated gaboxadol and its use for the treatment of psychiatric disorders |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2830083A (en) | 1953-04-29 | 1958-04-08 | Allied Chem & Dye Corp | Production of aryloxy aliphatic carboxylic acids |
| US3947579A (en) | 1974-06-03 | 1976-03-30 | Nelson Research & Development Company | Method and composition for potentiating neuroleptic drugs |
| US4084000A (en) | 1975-07-16 | 1978-04-11 | Nelson Research And Development Company | Method of treating schizophrenia |
| US4129652A (en) | 1976-08-16 | 1978-12-12 | Nelson Research & Development Company | Method for potentiating neuroleptic drugs |
| WO2003013514A1 (en) * | 2001-08-08 | 2003-02-20 | Carn-Aware Llc | Improving neurological functions |
| WO2008095221A1 (en) | 2007-02-07 | 2008-08-14 | Gosforth Centre (Holdings) Pty Ltd | Treatment of adhd |
| WO2009128057A2 (en) | 2008-04-18 | 2009-10-22 | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN et al | Psycho-pharmaceuticals |
| AU2009270799B2 (en) | 2008-07-18 | 2016-05-19 | Zafgen, Inc. | Methods of treating an overweight or obese subject |
| FR2935611B1 (fr) | 2008-09-10 | 2010-10-15 | Commissariat Energie Atomique | Utilisation d'agents anti-connexines pour moduler l'effet therapeutique de molecules psychotropes |
| ES2595251T3 (es) | 2010-05-25 | 2016-12-28 | Inserm - Institut National De La Santé Et De La Recherche Médicale | Métodos y composición farmacéutica para el tratamiento de un trastorno alimentario con inicio temprano en un paciente |
| GB201111712D0 (en) * | 2011-07-08 | 2011-08-24 | Gosforth Ct Holdings Pty Ltd | Pharmaceutical compositions |
| US9351968B1 (en) | 2015-09-09 | 2016-05-31 | Ovid Therapeutics Inc | Methods of treating developmental disorders using pipradrol |
| KR20190013737A (ko) * | 2016-05-26 | 2019-02-11 | 오비드 테라퓨틱스 인크. | 피프라드롤을 이용한 행동 증후군들의 치료 방법들 |
-
2015
- 2015-10-06 US US14/876,110 patent/US9351968B1/en not_active Expired - Fee Related
-
2016
- 2016-05-05 US US15/147,429 patent/US20170065572A1/en not_active Abandoned
- 2016-09-08 HK HK18114181.0A patent/HK1255132A1/zh unknown
- 2016-09-08 CA CA2997923A patent/CA2997923A1/en not_active Abandoned
- 2016-09-08 MX MX2018002906A patent/MX2018002906A/es unknown
- 2016-09-08 BR BR112018004680A patent/BR112018004680A2/pt not_active Application Discontinuation
- 2016-09-08 CN CN201680059513.7A patent/CN108366999A/zh active Pending
- 2016-09-08 EP EP16845019.5A patent/EP3331527A4/en not_active Withdrawn
- 2016-09-08 WO PCT/US2016/050702 patent/WO2017044578A1/en not_active Ceased
- 2016-09-08 AU AU2016318943A patent/AU2016318943A1/en not_active Abandoned
- 2016-09-08 KR KR1020187010048A patent/KR20180081710A/ko not_active Withdrawn
- 2016-09-08 JP JP2018512522A patent/JP2018528215A/ja active Pending
-
2017
- 2017-04-21 US US15/493,374 patent/US9913833B2/en active Active
-
2018
- 2018-01-31 US US15/884,699 patent/US20180147195A1/en not_active Abandoned
- 2018-03-07 IL IL257944A patent/IL257944B/en active IP Right Grant
-
2021
- 2021-04-22 IL IL282580A patent/IL282580A/en unknown
- 2021-04-26 IL IL282655A patent/IL282655A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20170065572A1 (en) | 2017-03-09 |
| US20180147195A1 (en) | 2018-05-31 |
| US20170216269A1 (en) | 2017-08-03 |
| US9913833B2 (en) | 2018-03-13 |
| CN108366999A (zh) | 2018-08-03 |
| EP3331527A4 (en) | 2019-04-10 |
| IL282655A (en) | 2021-06-30 |
| JP2018528215A (ja) | 2018-09-27 |
| WO2017044578A1 (en) | 2017-03-16 |
| IL257944A (en) | 2018-05-31 |
| IL282580A (en) | 2021-06-30 |
| BR112018004680A2 (pt) | 2018-09-25 |
| KR20180081710A (ko) | 2018-07-17 |
| CA2997923A1 (en) | 2017-03-16 |
| AU2016318943A1 (en) | 2018-04-05 |
| HK1255132A1 (zh) | 2019-08-09 |
| EP3331527A1 (en) | 2018-06-13 |
| IL257944B (en) | 2021-05-31 |
| US9351968B1 (en) | 2016-05-31 |
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