MX2018002221A - Dispositivo medico de inyeccion con camara limpiadora. - Google Patents
Dispositivo medico de inyeccion con camara limpiadora.Info
- Publication number
- MX2018002221A MX2018002221A MX2018002221A MX2018002221A MX2018002221A MX 2018002221 A MX2018002221 A MX 2018002221A MX 2018002221 A MX2018002221 A MX 2018002221A MX 2018002221 A MX2018002221 A MX 2018002221A MX 2018002221 A MX2018002221 A MX 2018002221A
- Authority
- MX
- Mexico
- Prior art keywords
- needle
- cleaning chamber
- injection device
- distal tip
- cleaning
- Prior art date
Links
- 238000004140 cleaning Methods 0.000 title abstract 5
- 238000010999 medical injection Methods 0.000 title 1
- 238000002347 injection Methods 0.000 abstract 3
- 239000007924 injection Substances 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 239000012459 cleaning agent Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/001—Apparatus specially adapted for cleaning or sterilising syringes or needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
- A61M5/286—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/31573—Accuracy improving means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/3257—Semi-automatic sleeve extension, i.e. in which triggering of the sleeve extension requires a deliberate action by the user, e.g. manual release of spring-biased extension means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/3271—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel with guiding tracks for controlled sliding of needle protective sleeve from needle exposing to needle covering position
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M2005/1787—Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
- A61M2005/3267—Biased sleeves where the needle is uncovered by insertion of the needle into a patient's body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/3278—Apparatus for destroying used needles or syringes
- A61M2005/3284—Deformaton of needle by deflection or bending
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Environmental & Geological Engineering (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
La invención es concerniente con un dispositivo de inyección para inyectar un medicamento líquido. El dispositivo de inyección comprende un conjunto de alojamiento que soporta un cartucho no removible que tiene una cámara interior que contiene el medicamento líquido a ser inyectado y una cánula de aguja reusable conectada al cartucho. Se provee además un conjunto de protección de aguja que tiene una cámara limpiadora que contiene un volumen de un agente limpiador para limpiar por lo menos la punta distal de la cánula de aguja entre inyecciones subsecuentes. El conjunto de protección de aguja es movible axialmente en una dirección proximal en relación con el conjunto de alojamiento desde una primera posición a una segunda posición, tras la rotación de por lo menos una parte del conjunto de protección de aguja, en donde la primera posición es una posición en la cual la punta distal de la cánula de aguja es colocada al interior de la cámara limpiadora, limpiando mediante esto la punta distal de la cánula de aguja y la segunda posición es una posición en la cual la punta distal de la cánula de aguja es colocada fuera y distal de la cámara limpiadora para igualar la presión en el cartucho.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15182290 | 2015-08-25 | ||
| PCT/EP2016/069004 WO2017032599A1 (en) | 2015-08-25 | 2016-08-10 | A medical injection device with a cleaning chamber |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2018002221A true MX2018002221A (es) | 2018-03-23 |
| MX379081B MX379081B (es) | 2025-03-11 |
Family
ID=53969305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018002221A MX379081B (es) | 2015-08-25 | 2016-08-10 | Dispositivo médico de inyección con cámara limpiadora. |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US11097046B2 (es) |
| EP (1) | EP3341044B1 (es) |
| JP (1) | JP6946268B2 (es) |
| KR (1) | KR20180048607A (es) |
| CN (1) | CN107921197B (es) |
| AU (1) | AU2016311047B2 (es) |
| BR (1) | BR112018002123A2 (es) |
| CA (1) | CA2996232A1 (es) |
| DK (1) | DK3341044T3 (es) |
| ES (1) | ES2773829T3 (es) |
| IL (1) | IL257174B (es) |
| MX (1) | MX379081B (es) |
| MY (1) | MY187439A (es) |
| PL (1) | PL3341044T3 (es) |
| RU (1) | RU2705900C2 (es) |
| WO (1) | WO2017032599A1 (es) |
| ZA (1) | ZA201800589B (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX379081B (es) * | 2015-08-25 | 2025-03-11 | Novo Nordisk As | Dispositivo médico de inyección con cámara limpiadora. |
| JP6949062B2 (ja) * | 2016-06-30 | 2021-10-13 | ノボ・ノルデイスク・エー/エス | 針洗浄をともなう医療注射デバイス |
| US11944791B2 (en) | 2017-08-30 | 2024-04-02 | Novo Nordisk A/S | Multi-use drug delivery device for drugs with less preservatives |
| CN111032117B (zh) * | 2017-08-30 | 2022-03-25 | 诺和诺德股份有限公司 | 具有防腐剂的流动连通单元 |
| WO2019043502A1 (en) * | 2017-09-04 | 2019-03-07 | Wockhardt Limited | SELF-INJECTOR WITH A NEEDLE HOOD |
| CN111148540A (zh) | 2017-09-25 | 2020-05-12 | 诺和诺德股份有限公司 | 具有清洁容器的注射装置 |
| WO2019101670A1 (en) * | 2017-11-21 | 2019-05-31 | Novo Nordisk A/S | An injection device with needle cleaning |
| CN112041003A (zh) | 2018-04-13 | 2020-12-04 | 诺和诺德股份有限公司 | 具有未连接构造和连接构造的流动连通单元 |
| JP2021526923A (ja) | 2018-06-15 | 2021-10-11 | ノボ・ノルデイスク・エー/エス | 医療用注射装置 |
| US20210128817A1 (en) * | 2018-06-29 | 2021-05-06 | Novo Nordisk A/S | Needle unit with biostatic chamber |
| WO2020011663A1 (en) | 2018-07-12 | 2020-01-16 | Novo Nordisk A/S | An injection device with an immobilization mechanism |
| EP3597237A1 (en) | 2018-07-18 | 2020-01-22 | Sanofi | Cartridge assembly for a drug delivery device and drug delivery device |
| CN112584880A (zh) * | 2018-08-20 | 2021-03-30 | 诺和诺德股份有限公司 | 用于注射装置的生物静态多次使用针头组件 |
| EP3894435A1 (en) | 2018-12-11 | 2021-10-20 | Sanofi | Insulin analogs having reduced insulin receptor binding affinity |
| US20220118184A1 (en) | 2019-01-04 | 2022-04-21 | Novo Nordisk A/S | A shield trigger mechanism and an injection device with a shield trigger mechanism |
| EP4034191A1 (en) * | 2019-09-24 | 2022-08-03 | Novo Nordisk A/S | Needle system for drug injection |
| USD950719S1 (en) * | 2020-03-12 | 2022-05-03 | Boston Scientific Scimed, Inc. | Tissue ligation device |
| CN115484998A (zh) | 2020-04-23 | 2022-12-16 | 诺和诺德股份有限公司 | 具有安全组件的可激活药物递送装置 |
| US20250041536A1 (en) * | 2021-12-15 | 2025-02-06 | Sanofi | Drug delivery arrangement comprising a tissue receiving element |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2888924A (en) * | 1958-02-25 | 1959-06-02 | Russell P Dunmire | Hypodermic syringes |
| US3354881A (en) | 1964-11-03 | 1967-11-28 | Universal Oil Prod Co | Hypodermic needle protector |
| GB2080689B (en) | 1980-07-29 | 1984-10-31 | Dent Hugh Robert | Sterilising fitments for injection devices |
| US4416663A (en) * | 1981-10-26 | 1983-11-22 | Steri-Pac, Inc. | Self-sterilizing hypodermic syringe |
| DK424485A (da) | 1984-09-21 | 1986-03-22 | Wellcome New Zealand | Hygiejnisk apparat til tilfoersel af et stof til og/eller til paafoering af en eller flere genstande paa et dyr |
| US4731059A (en) * | 1986-10-14 | 1988-03-15 | Medical Safety Products, Inc. | Combination needle shield/needle guard device positively locked onto detachable needle assemblies for an evacuated blood collection system and a hypodermic syringe |
| ES2015427A6 (es) * | 1989-07-21 | 1990-08-16 | Sempere Escudero Philippe | Dispositivo protector de alta seguridad para agujas de inyecciones. |
| US5383862A (en) | 1990-02-03 | 1995-01-24 | Telemedysis Inc | Method and device for enveloping and disinfecting of sharp instruments |
| US5312347A (en) | 1992-02-27 | 1994-05-17 | Osborne Barbara J | Hypodermic needle shield |
| US5591138A (en) * | 1995-08-10 | 1997-01-07 | Vaillancourt; Vincent L. | Protected needle assembly |
| PE20050438A1 (es) * | 2003-10-20 | 2005-06-14 | Esperion Therapeutics Inc | Formulas farmaceuticas, metodos y regimenes de dosificacion para el tratamiento y la prevencion de sindromes coronarios agudos |
| EP2438948B1 (en) * | 2004-11-24 | 2016-03-30 | SHL Group AB | Tubular rotator for a medicament injection device, and medicament injection device |
| PL1911480T3 (pl) | 2005-05-02 | 2010-02-26 | Elastomeric Systems S L | Strzykawka do aplikowania wielodawkowego z igłą wstrzykującą o sterylnym zabezpieczeniu |
| CN101568359B (zh) | 2006-12-22 | 2012-04-18 | 诺沃-诺迪斯克有限公司 | 带有被偏压的安全护罩的可防护针组件 |
| TWI393578B (zh) * | 2009-07-07 | 2013-04-21 | Shl Group Ab | 注射裝置 |
| JP5841051B2 (ja) | 2009-07-10 | 2016-01-06 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 制御された拍動的洗浄機能を有する洗浄用シリンジアセンブリ |
| US8663174B2 (en) * | 2009-11-13 | 2014-03-04 | Becton, Dickinson And Company | Hub assembly having a hidden needle for a drug delivery pen |
| CA2804087A1 (en) | 2010-07-02 | 2012-01-05 | Sanofi-Aventis Deutschland Gmbh | Injection device |
| EP2646088B1 (en) * | 2010-11-29 | 2018-08-01 | Sanofi-Aventis Deutschland GmbH | Medicated module with automatic reservoir engagement |
| CN103957968B (zh) * | 2011-08-30 | 2016-08-17 | 诺沃—诺迪斯克有限公司 | 用来依序递送流体体积的布置 |
| WO2014029018A1 (en) | 2012-08-23 | 2014-02-27 | 0736413 B.C. Ltd. | Disinfectant cap for hypodermic needles |
| EP2703026A1 (en) | 2012-09-04 | 2014-03-05 | Sanofi-Aventis Deutschland GmbH | Safety needle assembly |
| DK2911724T3 (da) * | 2012-10-25 | 2017-11-06 | Novo Nordisk As | For-fyldt engangs-injektionsapparat |
| US9636462B2 (en) * | 2012-11-02 | 2017-05-02 | Novo Nordisk A/S | Drug delivery device with shield operated needle actuator |
| US10335535B2 (en) * | 2013-10-31 | 2019-07-02 | Novo Nordisk A/S | Injection device with a needle cannula |
| MX379081B (es) * | 2015-08-25 | 2025-03-11 | Novo Nordisk As | Dispositivo médico de inyección con cámara limpiadora. |
-
2016
- 2016-08-10 MX MX2018002221A patent/MX379081B/es unknown
- 2016-08-10 CN CN201680049011.6A patent/CN107921197B/zh not_active Expired - Fee Related
- 2016-08-10 RU RU2018108381A patent/RU2705900C2/ru active
- 2016-08-10 JP JP2018510103A patent/JP6946268B2/ja not_active Expired - Fee Related
- 2016-08-10 CA CA2996232A patent/CA2996232A1/en not_active Withdrawn
- 2016-08-10 US US15/754,332 patent/US11097046B2/en not_active Expired - Fee Related
- 2016-08-10 PL PL16748310T patent/PL3341044T3/pl unknown
- 2016-08-10 MY MYPI2018700354A patent/MY187439A/en unknown
- 2016-08-10 DK DK16748310.6T patent/DK3341044T3/da active
- 2016-08-10 KR KR1020187003845A patent/KR20180048607A/ko not_active Withdrawn
- 2016-08-10 ES ES16748310T patent/ES2773829T3/es active Active
- 2016-08-10 AU AU2016311047A patent/AU2016311047B2/en not_active Ceased
- 2016-08-10 BR BR112018002123-7A patent/BR112018002123A2/pt active Search and Examination
- 2016-08-10 WO PCT/EP2016/069004 patent/WO2017032599A1/en not_active Ceased
- 2016-08-10 EP EP16748310.6A patent/EP3341044B1/en active Active
-
2018
- 2018-01-28 IL IL257174A patent/IL257174B/en unknown
- 2018-01-29 ZA ZA2018/00589A patent/ZA201800589B/en unknown
-
2021
- 2021-07-22 US US17/382,536 patent/US20210346594A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP3341044B1 (en) | 2020-01-29 |
| IL257174B (en) | 2021-07-29 |
| US20180243498A1 (en) | 2018-08-30 |
| RU2018108381A3 (es) | 2019-09-26 |
| KR20180048607A (ko) | 2018-05-10 |
| MY187439A (en) | 2021-09-22 |
| RU2018108381A (ru) | 2019-09-26 |
| AU2016311047B2 (en) | 2020-12-10 |
| IL257174A (en) | 2018-03-29 |
| CN107921197A (zh) | 2018-04-17 |
| EP3341044A1 (en) | 2018-07-04 |
| US20210346594A1 (en) | 2021-11-11 |
| ZA201800589B (en) | 2019-07-31 |
| CN107921197B (zh) | 2020-07-28 |
| PL3341044T3 (pl) | 2020-06-01 |
| US11097046B2 (en) | 2021-08-24 |
| RU2705900C2 (ru) | 2019-11-12 |
| MX379081B (es) | 2025-03-11 |
| AU2016311047A1 (en) | 2018-02-15 |
| DK3341044T3 (da) | 2020-02-17 |
| JP6946268B2 (ja) | 2021-10-06 |
| JP2018528813A (ja) | 2018-10-04 |
| WO2017032599A1 (en) | 2017-03-02 |
| ES2773829T3 (es) | 2020-07-15 |
| BR112018002123A2 (pt) | 2018-09-11 |
| CA2996232A1 (en) | 2017-03-02 |
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