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MX2018001502A - Receptor de antigeno quimerico y celulas t en las cuales se expresa el receptor de antigeno quimerico. - Google Patents

Receptor de antigeno quimerico y celulas t en las cuales se expresa el receptor de antigeno quimerico.

Info

Publication number
MX2018001502A
MX2018001502A MX2018001502A MX2018001502A MX2018001502A MX 2018001502 A MX2018001502 A MX 2018001502A MX 2018001502 A MX2018001502 A MX 2018001502A MX 2018001502 A MX2018001502 A MX 2018001502A MX 2018001502 A MX2018001502 A MX 2018001502A
Authority
MX
Mexico
Prior art keywords
receiver
chemeric
expressed
cells
chemeric antigen
Prior art date
Application number
MX2018001502A
Other languages
English (en)
Other versions
MX382532B (es
Inventor
Kong Seogkyoung
Original Assignee
Yoo Young Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yoo Young Pharm Co Ltd filed Critical Yoo Young Pharm Co Ltd
Publication of MX2018001502A publication Critical patent/MX2018001502A/es
Publication of MX382532B publication Critical patent/MX382532B/es

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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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Abstract

Se describe un receptor de antígeno quimérico que comprende: un dominio de unión a antígeno; una región de gozne; un dominio transmembrana; un dominio coestimulatorio; y dominio de señalización citoplásmica.
MX2018001502A 2015-08-05 2016-08-05 Receptor de antigeno quimerico y celulas t en las cuales se expresa el receptor de antigeno quimerico. MX382532B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20150110788 2015-08-05
PCT/KR2016/008632 WO2017023138A1 (ko) 2015-08-05 2016-08-05 키메라 항원 수용체 및 키메라 항원 수용체가 발현된 t 세포

Publications (2)

Publication Number Publication Date
MX2018001502A true MX2018001502A (es) 2018-08-01
MX382532B MX382532B (es) 2025-03-13

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MX2018001502A MX382532B (es) 2015-08-05 2016-08-05 Receptor de antigeno quimerico y celulas t en las cuales se expresa el receptor de antigeno quimerico.

Country Status (13)

Country Link
US (1) US10975148B2 (es)
EP (2) EP3575403A1 (es)
JP (1) JP6751493B2 (es)
KR (1) KR102011789B1 (es)
CN (1) CN108026534B (es)
AU (1) AU2016301932B2 (es)
CA (1) CA2994797C (es)
ES (1) ES2877090T3 (es)
IL (1) IL257295B (es)
MX (1) MX382532B (es)
RU (1) RU2724738C2 (es)
SG (2) SG10201912734PA (es)
WO (1) WO2017023138A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210252069A1 (en) * 2018-09-05 2021-08-19 Seogkyoung KONG Chimeric antigen receptor for solid cancer and t cells expressing chimeric antigen receptor
US20230092787A1 (en) * 2020-02-17 2023-03-23 University Of Virginia Patent Foundation Car t cells targeting the integrin alphav beta3 exhibit robust anti-tumor responses against gliomas and other solid tumor malignancies
CN113402612A (zh) 2020-03-17 2021-09-17 西比曼生物科技（香港）有限公司 靶向cd19和cd20的联合嵌合抗原受体及其应用
CN116178562A (zh) * 2021-11-29 2023-05-30 四川大学华西医院 基于efna1构建的嵌合抗原受体免疫细胞制备及其应用
CN114573711A (zh) * 2022-03-04 2022-06-03 陕西师范大学 一种TanCAR的构建及其应用
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